Garcia-Tejera, R., Tian, J. Y., Amoyel, M., Grima, R., Schumacher, L. J. (2025). Licensing and niche competition in spermatogenesis: mathematical models suggest complementary regulation of tissue maintenance. Development, 152(1) journals.biologists.com/dev/article/...
November 2, 2026 at 11:01 PM
Garcia-Tejera, R., Tian, J. Y., Amoyel, M., Grima, R., Schumacher, L. J. (2025). Licensing and niche competition in spermatogenesis: mathematical models suggest complementary regulation of tissue maintenance. Development, 152(1) journals.biologists.com/dev/article/...
Saya Nakagawa, Yoichi Furukawa, Kiyoshi Yamaguchi and colleagues find that BRD8 deficiency leads to progressive impairment of spermatogenesis in mice.
journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
November 5, 2026 at 10:24 AM
Saya Nakagawa, Yoichi Furukawa, Kiyoshi Yamaguchi and colleagues find that BRD8 deficiency leads to progressive impairment of spermatogenesis in mice.
journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
It’s a negative feedback loop, spermatogenesis is affected, and then there’s poor sperm or no sperm output because of that”.
'...manosphere misinformation working its way up to policy' #petehegseth
'...manosphere misinformation working its way up to policy' #petehegseth
November 1, 2026 at 4:34 PM
It’s a negative feedback loop, spermatogenesis is affected, and then there’s poor sperm or no sperm output because of that”.
'...manosphere misinformation working its way up to policy' #petehegseth
'...manosphere misinformation working its way up to policy' #petehegseth
Revealing the seminiferous epithelial cycle: 2,653 genes profiled in 867,062 mouse testis cells show Sertoli cells’ cyclic transcription syncs with spermatogenesis. PMID:42143021, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S009286742600471X #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S009286742600471X
No description available
www.cell.com
October 31, 2026 at 10:00 PM
A groundbreaking study profiles 2,653 genes in 867,062 mouse testis cells using seqFISH+, revealing a cyclical transcriptional pattern in Sertoli cells synchronized with spermatogenesis! PMID:42143021, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S009286742600471X #Medsky #Pharmsky #RNA 🧪
https://www.cell.com/cell/fulltext/S009286742600471X
No description available
www.cell.com
October 26, 2026 at 3:00 PM
A groundbreaking study profiles 2,653 genes in 867,062 mouse testis cells using seqFISH+, revealing a cyclical transcriptional pattern in Sertoli cells synchronized with spermatogenesis! PMID:42143021, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S009286742600471X #Medsky #Pharmsky #RNA 🧪
Extract: The EVOGEN team is seeking a postdoctoral researcher to study the role of HP1D2 in Drosophila spermatogenesis, focusing on its impact on sex-ratio meiotic drive.
October 24, 2026 at 10:03 AM
Extract: The EVOGEN team is seeking a postdoctoral researcher to study the role of HP1D2 in Drosophila spermatogenesis, focusing on its impact on sex-ratio meiotic drive.
RRID:AB_2535794 from @thermofishersci.bsky.social was used by authors in their Journal of Reproduction and Development paper. RRIDs improve reproducibility in scientific research. #ReproducibleResearch #OpenScience #accelerateopenscience
B3GALT4-dependent gangliosides are required for normal late spermatogenesis and male fertility
Read the full paper: B3GALT4-dependent gangliosides are required for normal late spermatogenesis and male fertility
doi.org
October 23, 2026 at 7:03 AM
RRID:AB_2535794 from @thermofishersci.bsky.social was used by authors in their Journal of Reproduction and Development paper. RRIDs improve reproducibility in scientific research. #ReproducibleResearch #OpenScience #accelerateopenscience
Revolutionary study profiles 2,653 genes in 867,062 mouse testis cells using seqFISH+, revealing a synchronized cyclic transcriptional pattern in Sertoli cells during spermatogenesis! PMID:42143021, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S009286742600471X #Medsky #Pharmsky #RNA #ASHG 🧪
https://www.cell.com/cell/fulltext/S009286742600471X
No description available
www.cell.com
October 22, 2026 at 6:00 PM
we're getting caught up on this example but i can provide other examples of searches where gemini is reliably wrong; for instance its answer to "does estradiol suppress spermatogenesis genes on the y chromosome" is reliably "no", which is incorrect
October 20, 2026 at 4:44 PM
we're getting caught up on this example but i can provide other examples of searches where gemini is reliably wrong; for instance its answer to "does estradiol suppress spermatogenesis genes on the y chromosome" is reliably "no", which is incorrect
A study profiled 2,653 genes in 867,062 mouse testis cells, unveiling dynamic transcriptional patterns in Sertoli cells synchronized with spermatogenesis. Insights into the seminiferous cycle are game-changing! PMID:42143021, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S009286742600471X
https://www.cell.com/cell/fulltext/S009286742600471X
No description available
www.cell.com
October 18, 2026 at 5:00 PM
A study profiled 2,653 genes in 867,062 mouse testis cells, unveiling dynamic transcriptional patterns in Sertoli cells synchronized with spermatogenesis. Insights into the seminiferous cycle are game-changing! PMID:42143021, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S009286742600471X
Dendrobium huoshanense ameliorates spermatogenesis disorder in rats through modulating m6A methylation modification and the NRF2-GPX4/TLR4-MyD88 signaling pathways
Journal of ethnopharmacology · Tao et al.
doi.org/10.1016/j.jep.2026.122499
#RNAsky #RNAmods
Journal of ethnopharmacology · Tao et al.
doi.org/10.1016/j.jep.2026.122499
#RNAsky #RNAmods
Dendrobium huoshanense ameliorates spermatogenesis disorder in rats through modulating m6A methylation modification and the NRF2-GPX4/TLR4-MyD88 signaling pathways
Journal of ethnopharmacology · Tao R, Li X, Ji L, Li Y, Su T, Ma M, Gu F, Yang L, Zang N, Chen C, Liu D, Lin Q.
doi.org
October 16, 2026 at 11:12 PM
Dendrobium huoshanense ameliorates spermatogenesis disorder in rats through modulating m6A methylation modification and the NRF2-GPX4/TLR4-MyD88 signaling pathways
Journal of ethnopharmacology · Tao et al.
doi.org/10.1016/j.jep.2026.122499
#RNAsky #RNAmods
Journal of ethnopharmacology · Tao et al.
doi.org/10.1016/j.jep.2026.122499
#RNAsky #RNAmods
RRIDs were included in this in bioRxiv paper. We value the author's support of reproducibility. #accelerateopenscience #OpenResearch #RRID
A genetic screen to identify novel interactions of the phosphatidylinositol phosphate signaling pathway in Drosophila spermatogenesis
Read the full paper: A genetic screen to identify novel interactions of the phosphatidylinositol phosphate signaling pathway in Drosophila spermatogenesis
doi.org
October 16, 2026 at 7:03 AM
RRIDs were included in this in bioRxiv paper. We value the author's support of reproducibility. #accelerateopenscience #OpenResearch #RRID
Most animal species pack sperm DNA with protamines instead of histones. Protamines are essential for male fertility. They are among the fastest-evolving genes in animals. That makes little sense. We think we know why, in a new paper led by @ching-hochang.bsky.social. www.science.org/doi/10.1126/...
Rapid protamine evolution suppresses meiotic drive in Drosophila
Many animal species replace histones with protamines during spermatogenesis. Although essential for sperm function, protamines evolve rapidly for reasons that remain unknown. Using in vivo gene replac...
www.science.org
October 10, 2026 at 7:44 PM
Most animal species pack sperm DNA with protamines instead of histones. Protamines are essential for male fertility. They are among the fastest-evolving genes in animals. That makes little sense. We think we know why, in a new paper led by @ching-hochang.bsky.social. www.science.org/doi/10.1126/...
Those X-bearing sperm dropped out during spermatogenesis. Males fathered more than 60% sons (sometimes 70%) instead of 50%. Mendel's fair coin is rigged in some way.
@ching-hochang.bsky.social actually predicted this very outcome in a previous paper: elifesciences.org/articles/85249
@ching-hochang.bsky.social actually predicted this very outcome in a previous paper: elifesciences.org/articles/85249
October 10, 2026 at 7:48 PM
Those X-bearing sperm dropped out during spermatogenesis. Males fathered more than 60% sons (sometimes 70%) instead of 50%. Mendel's fair coin is rigged in some way.
@ching-hochang.bsky.social actually predicted this very outcome in a previous paper: elifesciences.org/articles/85249
@ching-hochang.bsky.social actually predicted this very outcome in a previous paper: elifesciences.org/articles/85249
A paper using RRID:AB_2536863 from @thermofishersci.bsky.social was just published in iScience. Thanks for making your methods matter! #accelerateopenscience #ReproducibleResearch #STMpublishing
LncRNA Arsa-DT is required for spermatogenesis and male fertility by regulating G2/M progression
Read the full paper: LncRNA Arsa-DT is required for spermatogenesis and male fertility by regulating G2/M progression
doi.org
October 10, 2026 at 7:00 AM
A paper using RRID:AB_2536863 from @thermofishersci.bsky.social was just published in iScience. Thanks for making your methods matter! #accelerateopenscience #ReproducibleResearch #STMpublishing
The question worth asking:
Could severe inflammation before puberty affect reproductive health in boys? No one knows.
Long-term follow-up of children infected with COVID before puberty will be important.
Wu et al., Molecular Human Reproduction 2026 buff.ly/gLds0FD
Could severe inflammation before puberty affect reproductive health in boys? No one knows.
Long-term follow-up of children infected with COVID before puberty will be important.
Wu et al., Molecular Human Reproduction 2026 buff.ly/gLds0FD
Prepubertal exposure to SARS-CoV-2 single-stranded RNA disrupts spermatogenesis and causes intergenerational effects in mice
Abstract. The COVID-19 pandemic has caused widespread morbidity and mortality worldwide, with emerging evidence documenting transient reproductive impairme
buff.ly
October 9, 2026 at 8:19 PM
The question worth asking:
Could severe inflammation before puberty affect reproductive health in boys? No one knows.
Long-term follow-up of children infected with COVID before puberty will be important.
Wu et al., Molecular Human Reproduction 2026 buff.ly/gLds0FD
Could severe inflammation before puberty affect reproductive health in boys? No one knows.
Long-term follow-up of children infected with COVID before puberty will be important.
Wu et al., Molecular Human Reproduction 2026 buff.ly/gLds0FD
@harmitmalik.bsky.social Nice, www.science.org/doi/10.1126/.... My first paper was on Mst77F/Y 😎 doi.org/10.1093/gene...
Rapid protamine evolution suppresses meiotic drive in Drosophila
Many animal species replace histones with protamines during spermatogenesis. Although essential for sperm function, protamines evolve rapidly for reasons that remain unknown. Using in vivo gene replac...
www.science.org
October 9, 2026 at 11:17 AM
@harmitmalik.bsky.social Nice, www.science.org/doi/10.1126/.... My first paper was on Mst77F/Y 😎 doi.org/10.1093/gene...
Rapid protamine evolution suppresses meiotic drive in Drosophila | Science Advances www.science.org/doi/10.1126/...
Rapid protamine evolution suppresses meiotic drive in Drosophila
Many animal species replace histones with protamines during spermatogenesis. Although essential for sperm function, protamines evolve rapidly for reasons that remain unknown. Using in vivo gene replac...
www.science.org
October 8, 2026 at 12:41 PM
Rapid protamine evolution suppresses meiotic drive in Drosophila | Science Advances www.science.org/doi/10.1126/...
Revealing the seminiferous epithelial cycle using seqFISH+, a study profiled 2,653 genes in 867,062 mouse testis cells to show Sertoli cells sync their transcriptional patterns with spermatogenesis. PMID:42143021, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S009286742600471X #Medsky #RNA 🧪
https://www.cell.com/cell/fulltext/S009286742600471X
No description available
www.cell.com
October 9, 2026 at 1:00 PM
Revealing the seminiferous epithelial cycle using seqFISH+, a study profiled 2,653 genes in 867,062 mouse testis cells to show Sertoli cells sync their transcriptional patterns with spermatogenesis. PMID:42143021, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S009286742600471X #Medsky #RNA 🧪
Thrilled to share that our paper is finally out in Science Advances!
🔗 www.science.org/doi/10.1126/...
TL;DR: A Drosophila protamine acts as shields resolving conflict between X and Y chromosomes. Disruption unleashes meiotic drive that kills X-bearing sperm and skews progeny sex ratios. 🪰🧬ᯡ
🔗 www.science.org/doi/10.1126/...
TL;DR: A Drosophila protamine acts as shields resolving conflict between X and Y chromosomes. Disruption unleashes meiotic drive that kills X-bearing sperm and skews progeny sex ratios. 🪰🧬ᯡ
Rapid protamine evolution suppresses meiotic drive in Drosophila
Many animal species replace histones with protamines during spermatogenesis. Although essential for sperm function, protamines evolve rapidly for reasons that remain unknown. Using in vivo gene replac...
www.science.org
October 8, 2026 at 1:23 AM
Thrilled to share that our paper is finally out in Science Advances!
🔗 www.science.org/doi/10.1126/...
TL;DR: A Drosophila protamine acts as shields resolving conflict between X and Y chromosomes. Disruption unleashes meiotic drive that kills X-bearing sperm and skews progeny sex ratios. 🪰🧬ᯡ
🔗 www.science.org/doi/10.1126/...
TL;DR: A Drosophila protamine acts as shields resolving conflict between X and Y chromosomes. Disruption unleashes meiotic drive that kills X-bearing sperm and skews progeny sex ratios. 🪰🧬ᯡ
RRIDs were included in this in Cellular & Molecular Biology Letters paper. Thanks for making your methods matter! #accelerateopenscience #BetterScience #OpenResearch
G-quadruplex structures are key regulators of mammalian spermatogenesis
Read the full paper: G-quadruplex structures are key regulators of mammalian spermatogenesis
doi.org
October 8, 2026 at 7:04 AM
RRIDs were included in this in Cellular & Molecular Biology Letters paper. Thanks for making your methods matter! #accelerateopenscience #BetterScience #OpenResearch
Oh FFS those of us who research the health harms of climate change don’t even need Google. Here ya go 👇. Also did anybody check area security and ring camera feeds for the 18 days in question?
October 7, 2026 at 2:59 PM
Oh FFS those of us who research the health harms of climate change don’t even need Google. Here ya go 👇. Also did anybody check area security and ring camera feeds for the 18 days in question?
Researchers found SARS-CoV-2 GU-rich RNA triggered inflammation in young mice that damaged the blood-testis barrier, disrupted sperm development and altered metabolism in their offspring.
academic.oup.com/molehr/advan...
academic.oup.com/molehr/advan...
Prepubertal exposure to SARS-CoV-2 single-stranded RNA disrupts spermatogenesis and causes intergenerational effects in mice
Abstract. The COVID-19 pandemic has caused widespread morbidity and mortality worldwide, with emerging evidence documenting transient reproductive impairme
academic.oup.com
October 6, 2026 at 4:23 PM
Researchers found SARS-CoV-2 GU-rich RNA triggered inflammation in young mice that damaged the blood-testis barrier, disrupted sperm development and altered metabolism in their offspring.
academic.oup.com/molehr/advan...
academic.oup.com/molehr/advan...
Our colleagues at the Dept. of Morphology and Cell Biology, Univ. of Oviedo, have published exciting research on SOD2 deficiency and spermatogenesis. Thank you for allowing us to collaborate!
buff.ly/qT4Pn6F
#mice #SOD #spermatogenesis #MaleFertility
buff.ly/qT4Pn6F
#mice #SOD #spermatogenesis #MaleFertility
https://doi.org/10.1016/j.freeradbiomed.2026.09.020
buff.ly
October 5, 2026 at 11:19 AM
Our colleagues at the Dept. of Morphology and Cell Biology, Univ. of Oviedo, have published exciting research on SOD2 deficiency and spermatogenesis. Thank you for allowing us to collaborate!
buff.ly/qT4Pn6F
#mice #SOD #spermatogenesis #MaleFertility
buff.ly/qT4Pn6F
#mice #SOD #spermatogenesis #MaleFertility