💉 #diabetes #EASD2026
🇺🇸 #$LLY #Onswik and 🇩🇰 #$NOVO #Awiqli are racing for the flat half of the business. Novo's insulin: EUR 1.7bn a quarter, flat since 2020. Incretins: Novo EUR 8.0bn, Lilly EUR 13.8bn.
New post, with ACHIEVE-4:
midgardfinance.com/blog/2026/10/01/weekly-insulin-onswik-awiqli/
🇺🇸 #$LLY #Onswik and 🇩🇰 #$NOVO #Awiqli are racing for the flat half of the business. Novo's insulin: EUR 1.7bn a quarter, flat since 2020. Incretins: Novo EUR 8.0bn, Lilly EUR 13.8bn.
New post, with ACHIEVE-4:
midgardfinance.com/blog/2026/10/01/weekly-insulin-onswik-awiqli/
October 2, 2026 at 9:30 AM
✨New issue✨
Check out the latest in #Metabolism research from across all disciplines.
Read about #AdiposeTissue, #EVs, #Incretins, #Immune cells, #LiverMetabolism, #MitochondrialMetabolism, #SpatialOmics, #Tumorbiology and many more topics! 🧪
http://dlvr.it/TRmC3C
Check out the latest in #Metabolism research from across all disciplines.
Read about #AdiposeTissue, #EVs, #Incretins, #Immune cells, #LiverMetabolism, #MitochondrialMetabolism, #SpatialOmics, #Tumorbiology and many more topics! 🧪
http://dlvr.it/TRmC3C
March 29, 2026 at 4:01 PM
✨New issue✨
Check out the latest in #Metabolism research from across all disciplines.
Read about #AdiposeTissue, #EVs, #Incretins, #Immune cells, #LiverMetabolism, #MitochondrialMetabolism, #SpatialOmics, #Tumorbiology and many more topics! 🧪
http://dlvr.it/TRmC3C
Check out the latest in #Metabolism research from across all disciplines.
Read about #AdiposeTissue, #EVs, #Incretins, #Immune cells, #LiverMetabolism, #MitochondrialMetabolism, #SpatialOmics, #Tumorbiology and many more topics! 🧪
http://dlvr.it/TRmC3C
Random endocrine function physiology slide about GLP-1 and GIP (the incretins)
November 10, 2024 at 2:33 AM
Random endocrine function physiology slide about GLP-1 and GIP (the incretins)
Oh hey. I'm part of a thing that's not incretins(I'll still find a way to incorporate them into #NephJC )
✨Exciting news #NephtSky
The new #NephJC editorial interns are here!
📢Give them a follow and make them feel at home
👉 @drbarbateba.bsky.social @ancast13.bsky.social @kiddokidney.bsky.social @andrewdelaat.bsky.social @farahwehbe92.bsky.social 👇👇
www.nephjc.com/news/2025/6/...
The new #NephJC editorial interns are here!
📢Give them a follow and make them feel at home
👉 @drbarbateba.bsky.social @ancast13.bsky.social @kiddokidney.bsky.social @andrewdelaat.bsky.social @farahwehbe92.bsky.social 👇👇
www.nephjc.com/news/2025/6/...
NephJC Internship 2026-2027 — NephJC
Introducing NephJC’s brand new editorial internship class of 2026-2027
www.nephjc.com
May 28, 2026 at 11:13 PM
Oh hey. I'm part of a thing that's not incretins(I'll still find a way to incorporate them into #NephJC )
Camurus and Lilly enter collaboration and license agreement for long-acting FluidCrystal® incretins #Weightloss Selected from dual GIP and GLP-1 receptor agonists, triple GIP, glucagon and GLP-1 receptor agonists, and an option to include amylin receptor agonists. www.camurus.com/media/press-...
Camurus and Lilly enter collaboration and license agreement for long-acting FluidCrystal® incretins - Camurus
www.camurus.com
June 4, 2025 at 1:26 PM
Camurus and Lilly enter collaboration and license agreement for long-acting FluidCrystal® incretins #Weightloss Selected from dual GIP and GLP-1 receptor agonists, triple GIP, glucagon and GLP-1 receptor agonists, and an option to include amylin receptor agonists. www.camurus.com/media/press-...
I deeply enjoyed getting to talk about Gila monster venom in a lecture about incretins and GLP-1 receptor agonists! 👹
This is the most relevant article to NIH and research cuts I’ve seen.
Imagine if this was today , how many people would be saying “Why are we studying Gila Monsters and their impact on diabetes ? That’s wasted money !”
globalnews.ca/news/9793403...
Imagine if this was today , how many people would be saying “Why are we studying Gila Monsters and their impact on diabetes ? That’s wasted money !”
globalnews.ca/news/9793403...
How a Canadian scientist and a venomous lizard helped pave the way for Ozempic - National | Globalnews.ca
In 1984, Dr. Daniel Drucker, an endocrinologist from the University of Toronto, discovered a hormone that helped pave the way for popular diabetes drugs such as Ozempic.
globalnews.ca
February 9, 2025 at 10:31 PM
I deeply enjoyed getting to talk about Gila monster venom in a lecture about incretins and GLP-1 receptor agonists! 👹
November 11, 2024 at 3:32 AM
Beyond a singular focus on GLP-1: why we need a new nomenclature now www.thelancet.com/journals/lan...
#GLP-1 receptor agonists #incretins
#obesity type 2 #diabetes #T2D
#MedSky #EndoSky
#GLP-1 receptor agonists #incretins
#obesity type 2 #diabetes #T2D
#MedSky #EndoSky
January 4, 2026 at 12:06 PM
Beyond a singular focus on GLP-1: why we need a new nomenclature now www.thelancet.com/journals/lan...
#GLP-1 receptor agonists #incretins
#obesity type 2 #diabetes #T2D
#MedSky #EndoSky
#GLP-1 receptor agonists #incretins
#obesity type 2 #diabetes #T2D
#MedSky #EndoSky
✨New issue✨
Check out the latest in #Metabolism research from across all disciplines
Read about #Adiposity&Cancer, #NAD+, #Food perception, #Incretins, #Tcells, #AlzheimersDisease, #Succinate and many more topics! 🧪
http://dlvr.it/TTDYLz
Check out the latest in #Metabolism research from across all disciplines
Read about #Adiposity&Cancer, #NAD+, #Food perception, #Incretins, #Tcells, #AlzheimersDisease, #Succinate and many more topics! 🧪
http://dlvr.it/TTDYLz
June 26, 2026 at 3:02 PM
✨New issue✨
Check out the latest in #Metabolism research from across all disciplines
Read about #Adiposity&Cancer, #NAD+, #Food perception, #Incretins, #Tcells, #AlzheimersDisease, #Succinate and many more topics! 🧪
http://dlvr.it/TTDYLz
Check out the latest in #Metabolism research from across all disciplines
Read about #Adiposity&Cancer, #NAD+, #Food perception, #Incretins, #Tcells, #AlzheimersDisease, #Succinate and many more topics! 🧪
http://dlvr.it/TTDYLz
So I have thoughts, which of course connect to incretins like GIP and GLP-1, along with NREM2, glymphatic clearance, and the cNTS (a structure in the medulla).
First, GIP has been shown to be correlated with hr increases and glucose levels in POTS, often leading to reactive hypoglycemia.
First, GIP has been shown to be correlated with hr increases and glucose levels in POTS, often leading to reactive hypoglycemia.
Not to overshare, but I've been pretty open about my confusing crash that started on 6/19.
In the 'just thinking about things' category, on 5/14, I started 1MG of Rapamycin. Unfortunately I developed GI pain on 5/19 and had to stop. My GI doctor tested my calprotectin, and it..
In the 'just thinking about things' category, on 5/14, I started 1MG of Rapamycin. Unfortunately I developed GI pain on 5/19 and had to stop. My GI doctor tested my calprotectin, and it..
Hey #NEISvoid & friends - first PEM crash in a long time here. Thought I had paced well with Visible and Garmin body battery, but this crash snuck up on me. I’m currently following Bateman Horne Center’s Crash Survival Guide as best I can (radical rest, reducing stimulation
July 13, 2025 at 5:50 PM
So I have thoughts, which of course connect to incretins like GIP and GLP-1, along with NREM2, glymphatic clearance, and the cNTS (a structure in the medulla).
First, GIP has been shown to be correlated with hr increases and glucose levels in POTS, often leading to reactive hypoglycemia.
First, GIP has been shown to be correlated with hr increases and glucose levels in POTS, often leading to reactive hypoglycemia.
It's live, it's 6,000 words and it still feels incomplete but it's done! GLP1 and the kidneys! Glucagon, vasopressin, urea, sodium, macula densa, and so much more. If you like it please share it. The goal of this was to bring together decades of research. The earliest paper I used is from 1958!
GLP-1 and the kidneys
Incretins are changing the narrative of chronic kidney disease
the-incretins.beehiiv.com
December 16, 2025 at 5:55 PM
It's live, it's 6,000 words and it still feels incomplete but it's done! GLP1 and the kidneys! Glucagon, vasopressin, urea, sodium, macula densa, and so much more. If you like it please share it. The goal of this was to bring together decades of research. The earliest paper I used is from 1958!
SURMOUNT-5 topline data by @elilillyandco.bsky.social show #tirzepatide > TBW loss than #semaglutide at 72 wks
My liver-centric perspective, up to 30% Americans will be on incretins by 2030.
We need #MASH drugs that work in a background of incretins not in competition with them.
#liversky
My liver-centric perspective, up to 30% Americans will be on incretins by 2030.
We need #MASH drugs that work in a background of incretins not in competition with them.
#liversky
December 6, 2024 at 1:38 PM
SURMOUNT-5 topline data by @elilillyandco.bsky.social show #tirzepatide > TBW loss than #semaglutide at 72 wks
My liver-centric perspective, up to 30% Americans will be on incretins by 2030.
We need #MASH drugs that work in a background of incretins not in competition with them.
#liversky
My liver-centric perspective, up to 30% Americans will be on incretins by 2030.
We need #MASH drugs that work in a background of incretins not in competition with them.
#liversky
So long acting incretins sound like a brilliant idea ...until you remember that women are going to get pregnant while on weightloss drugs. At least with a weekly injection you can stop taking them.
endpoints.news/eli-lilly-in...
endpoints.news/eli-lilly-in...
Lilly makes a move for long-acting incretins in tech deal with Swedish biotech
Eli Lilly has tapped Camurus in a deal worth up to $870 million for its drug delivery technology to develop four long-acting incretin candidates.
endpoints.news
June 5, 2025 at 10:39 AM
So long acting incretins sound like a brilliant idea ...until you remember that women are going to get pregnant while on weightloss drugs. At least with a weekly injection you can stop taking them.
endpoints.news/eli-lilly-in...
endpoints.news/eli-lilly-in...
As understanding of the gut–bone axis deepens, there is growing interest in leveraging its effects to develop innovative strategies for preventing and treating bone fragility in the future www.thelancet.com/journals/lan...
#osteoporosis #weightloss #incretins
#MedSky #EndoSky #GastroSky #RheumSky
#osteoporosis #weightloss #incretins
#MedSky #EndoSky #GastroSky #RheumSky
April 7, 2025 at 9:36 AM
As understanding of the gut–bone axis deepens, there is growing interest in leveraging its effects to develop innovative strategies for preventing and treating bone fragility in the future www.thelancet.com/journals/lan...
#osteoporosis #weightloss #incretins
#MedSky #EndoSky #GastroSky #RheumSky
#osteoporosis #weightloss #incretins
#MedSky #EndoSky #GastroSky #RheumSky
Reprogramming the mitochondrial–circadian energy code with incretins
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
March 31, 2026 at 3:51 PM
Reprogramming the mitochondrial–circadian energy code with incretins
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Incretins are fantastic drugs. Glad it’s working for you.
May 4, 2026 at 10:48 AM
Incretins are fantastic drugs. Glad it’s working for you.
Incretin hormones GLP-1 and GIP connect #metabolism and cardiovascular #health. Our new REVIEW highlights the latest about how endogenous incretins shape cardiometabolic disease @dream-diabetes.bsky.social @um-pharmacology.bsky.social @um-radyfhs.bsky.social cdnsciencepub.com/doi/10.1139/...
March 16, 2026 at 8:44 PM
Incretin hormones GLP-1 and GIP connect #metabolism and cardiovascular #health. Our new REVIEW highlights the latest about how endogenous incretins shape cardiometabolic disease @dream-diabetes.bsky.social @um-pharmacology.bsky.social @um-radyfhs.bsky.social cdnsciencepub.com/doi/10.1139/...
Hmm may as well! 2026 is gonna be a wild year for CKD and incretins! Between this and becoming a hypertension nerd I should!
December 16, 2025 at 9:52 PM
Hmm may as well! 2026 is gonna be a wild year for CKD and incretins! Between this and becoming a hypertension nerd I should!
Incretin hormones—glucagon-like peptide-1 (GLP-1) & glucose-dependent insulinotropic peptide (GIP)—act as a critical link connecting #digestion, #metabolism, & #cardiovascular function, supporting physiological adaptations to nutrient intake thelancet.com/journals/lan...
#incretins
#MedSky #EndoSky
#incretins
#MedSky #EndoSky
December 13, 2025 at 2:09 PM
Incretin hormones—glucagon-like peptide-1 (GLP-1) & glucose-dependent insulinotropic peptide (GIP)—act as a critical link connecting #digestion, #metabolism, & #cardiovascular function, supporting physiological adaptations to nutrient intake thelancet.com/journals/lan...
#incretins
#MedSky #EndoSky
#incretins
#MedSky #EndoSky
Incretin-based therapies are becoming a core component of diabetes care.
By linking digestion, metabolism, & cardiovascular function, incretin-based therapies can help reduce morbidity & mortality.
Find out more in @thelancetendo.bsky.social: tinyurl.com/dvtv7j28
By linking digestion, metabolism, & cardiovascular function, incretin-based therapies can help reduce morbidity & mortality.
Find out more in @thelancetendo.bsky.social: tinyurl.com/dvtv7j28
October 6, 2025 at 12:34 PM
Incretin-based therapies are becoming a core component of diabetes care.
By linking digestion, metabolism, & cardiovascular function, incretin-based therapies can help reduce morbidity & mortality.
Find out more in @thelancetendo.bsky.social: tinyurl.com/dvtv7j28
By linking digestion, metabolism, & cardiovascular function, incretin-based therapies can help reduce morbidity & mortality.
Find out more in @thelancetendo.bsky.social: tinyurl.com/dvtv7j28
By linking #digestion, #metabolism, & #cardiovascular health, #incretin-based therapies do more than just regulate blood sugar; they help reduce morbidity & mortality & are becoming a core component of modern #diabetes care www.thelancet.com/journals/lan...
#GLP-1 #GIP
#MedSky #EndoSky #CardioSky
#GLP-1 #GIP
#MedSky #EndoSky #CardioSky
May 25, 2026 at 11:45 AM
By linking #digestion, #metabolism, & #cardiovascular health, #incretin-based therapies do more than just regulate blood sugar; they help reduce morbidity & mortality & are becoming a core component of modern #diabetes care www.thelancet.com/journals/lan...
#GLP-1 #GIP
#MedSky #EndoSky #CardioSky
#GLP-1 #GIP
#MedSky #EndoSky #CardioSky
Incretin-based therapies are becoming a core component of diabetes care.
By linking digestion, metabolism, & cardiovascular function, incretin-based therapies can help reduce morbidity & mortality.
Find out more in @thelancetendo.bsky.social: tinyurl.com/dvtv7j28
By linking digestion, metabolism, & cardiovascular function, incretin-based therapies can help reduce morbidity & mortality.
Find out more in @thelancetendo.bsky.social: tinyurl.com/dvtv7j28
July 14, 2025 at 10:37 AM
Incretin-based therapies are becoming a core component of diabetes care.
By linking digestion, metabolism, & cardiovascular function, incretin-based therapies can help reduce morbidity & mortality.
Find out more in @thelancetendo.bsky.social: tinyurl.com/dvtv7j28
By linking digestion, metabolism, & cardiovascular function, incretin-based therapies can help reduce morbidity & mortality.
Find out more in @thelancetendo.bsky.social: tinyurl.com/dvtv7j28
We still haven't figured out what to call the new weight loss drugs and that's driving the problem.
GLP1 meds? Incretins? Nutrient stimulated hormones(NuSH) ??
The use of peptides drives me nuts as well.
GLP1 meds? Incretins? Nutrient stimulated hormones(NuSH) ??
The use of peptides drives me nuts as well.
May 5, 2026 at 9:30 PM
We still haven't figured out what to call the new weight loss drugs and that's driving the problem.
GLP1 meds? Incretins? Nutrient stimulated hormones(NuSH) ??
The use of peptides drives me nuts as well.
GLP1 meds? Incretins? Nutrient stimulated hormones(NuSH) ??
The use of peptides drives me nuts as well.
Taking politics out of this, incretins need to be made more affordable. True
Incretins are not for everyone and lifestyle modification is needed. Also true.
Public health, diabetology and obesity experts are best qualified to make wide ranging decisions. Definitely true
#liversky
Incretins are not for everyone and lifestyle modification is needed. Also true.
Public health, diabetology and obesity experts are best qualified to make wide ranging decisions. Definitely true
#liversky
December 18, 2024 at 11:09 PM
Taking politics out of this, incretins need to be made more affordable. True
Incretins are not for everyone and lifestyle modification is needed. Also true.
Public health, diabetology and obesity experts are best qualified to make wide ranging decisions. Definitely true
#liversky
Incretins are not for everyone and lifestyle modification is needed. Also true.
Public health, diabetology and obesity experts are best qualified to make wide ranging decisions. Definitely true
#liversky
#obesity ARO-ALK7 targeting #ALK7 in fat cells is equally/more effective in adipose tissue loss than the incretins...
...by causing increased energy expenditure (not because u want to vomit+starving yourself). Personally, I'd just take ARO-ALK7 and not bother about incretins.
...by causing increased energy expenditure (not because u want to vomit+starving yourself). Personally, I'd just take ARO-ALK7 and not bother about incretins.
February 28, 2025 at 8:13 PM