We have a preprint of a book chapter for you: Structural Analysis of Membrane Proteins in Cell-Derived Microvesicles.
We describe how to image membrane proteins in mid-sized vesicles using cryo-electron tomography
zenodo.org/records/1717...
We describe how to image membrane proteins in mid-sized vesicles using cryo-electron tomography
zenodo.org/records/1717...
Structural Analysis of Membrane Proteins in Cell-Derived Microvesicles
zenodo.org
September 22, 2025 at 12:36 PM
We have a preprint of a book chapter for you: Structural Analysis of Membrane Proteins in Cell-Derived Microvesicles.
We describe how to image membrane proteins in mid-sized vesicles using cryo-electron tomography
zenodo.org/records/1717...
We describe how to image membrane proteins in mid-sized vesicles using cryo-electron tomography
zenodo.org/records/1717...
Japanese scientists developed a universal artificial blood based on hemoglobin microvesicles that successfully saved 60% of animal subjects from lethal bleeding, potentially eliminating blood-type compatibility barriers.
June 27, 2026 at 4:00 PM
Japanese scientists developed a universal artificial blood based on hemoglobin microvesicles that successfully saved 60% of animal subjects from lethal bleeding, potentially eliminating blood-type compatibility barriers.
First attempt at a starter pack for EV people - surprisingly difficult to find everyone!
Comment if you want to be added to the list 👇
#extracellularvesicles #exosomes #microvesicles
Comment if you want to be added to the list 👇
#extracellularvesicles #exosomes #microvesicles
November 13, 2024 at 2:41 PM
First attempt at a starter pack for EV people - surprisingly difficult to find everyone!
Comment if you want to be added to the list 👇
#extracellularvesicles #exosomes #microvesicles
Comment if you want to be added to the list 👇
#extracellularvesicles #exosomes #microvesicles
☕Jeppesen, Sanchez, Burnette (@mag2art.bsky.social) & co identify #blebbisomes as large membrane-enclosed vesicles containing #organelles and secreted by cells. Blebbisomes can both secrete and internalize #exosomes and microvesicles. #CellBiology
bit.ly/3FBxqme
bit.ly/3FBxqme
Blebbisomes are large, organelle-rich extracellular vesicles with cell-like properties - Nature Cell Biology
Jeppesen, Sanchez et al. identify blebbisomes as large membrane-enclosed vesicles containing organelles and secreted by cells. Blebbisomes can both secrete and internalize exosomes and microvesicles.
bit.ly
March 26, 2025 at 1:17 PM
☕Jeppesen, Sanchez, Burnette (@mag2art.bsky.social) & co identify #blebbisomes as large membrane-enclosed vesicles containing #organelles and secreted by cells. Blebbisomes can both secrete and internalize #exosomes and microvesicles. #CellBiology
bit.ly/3FBxqme
bit.ly/3FBxqme
Happy to announce on my first bsky post that today our manuscript “The endocannabinoid 2-arachidonoylglycerol is released and transported on demand via extracellular microvesicles” has been published in its final form in PNAS n/1
www.pnas.org
February 21, 2025 at 2:34 PM
Happy to announce on my first bsky post that today our manuscript “The endocannabinoid 2-arachidonoylglycerol is released and transported on demand via extracellular microvesicles” has been published in its final form in PNAS n/1
Blebbisomes are large, organelle-rich extracellular vesicles with cell-like properties
🔘 Form with functional mitochondria.
🔘 Are distinct from large oncosomes.
🔘 Contain multiple organelles.
🔘 Secrete exosomes and microvesicles.
www.nature.com/articles/s41...
🔘 Form with functional mitochondria.
🔘 Are distinct from large oncosomes.
🔘 Contain multiple organelles.
🔘 Secrete exosomes and microvesicles.
www.nature.com/articles/s41...
February 22, 2025 at 1:14 AM
Blebbisomes are large, organelle-rich extracellular vesicles with cell-like properties
🔘 Form with functional mitochondria.
🔘 Are distinct from large oncosomes.
🔘 Contain multiple organelles.
🔘 Secrete exosomes and microvesicles.
www.nature.com/articles/s41...
🔘 Form with functional mitochondria.
🔘 Are distinct from large oncosomes.
🔘 Contain multiple organelles.
🔘 Secrete exosomes and microvesicles.
www.nature.com/articles/s41...
Forgot the magic word: #ExtracellularVesicles!
#exosomes #microvesicles #scicomm #podcast #science #research
#exosomes #microvesicles #scicomm #podcast #science #research
To round out Season 1 of the #rEView podcast, @dylanburger.bsky.social and I talk about Effective Science Communication 🤓 🙌
Dylan is on the ISEV board of directors and is a member of the ISEV Communications and Membership committee.
youtu.be/Oqph3T6i_oI?...
Dylan is on the ISEV board of directors and is a member of the ISEV Communications and Membership committee.
youtu.be/Oqph3T6i_oI?...
Ep10 - Extracellular Vesicles - rEView Podcast - Dylan Burger
YouTube video by rEView
youtu.be
December 3, 2024 at 3:42 AM
Forgot the magic word: #ExtracellularVesicles!
#exosomes #microvesicles #scicomm #podcast #science #research
#exosomes #microvesicles #scicomm #podcast #science #research
Great to see a lot of familiar faces joining the extracellular vesicles community on here 👋
Don’t forget to follow the Extracellular Vesicles feed for all things exosomes, ectosomes, microvesicles, apoptotic bodies, and more…
Don’t forget to follow the Extracellular Vesicles feed for all things exosomes, ectosomes, microvesicles, apoptotic bodies, and more…
November 24, 2024 at 1:57 AM
Great to see a lot of familiar faces joining the extracellular vesicles community on here 👋
Don’t forget to follow the Extracellular Vesicles feed for all things exosomes, ectosomes, microvesicles, apoptotic bodies, and more…
Don’t forget to follow the Extracellular Vesicles feed for all things exosomes, ectosomes, microvesicles, apoptotic bodies, and more…
Selective Packaging of Rotavirus Double-Layered Particles into Host Microvesicles
RV infection strongly increases host microvesicle production, and these vesicles are enriched for DLPs even though the intracellular viral population is dominated by TLPs.
www.biorxiv.org/content/10.6...
RV infection strongly increases host microvesicle production, and these vesicles are enriched for DLPs even though the intracellular viral population is dominated by TLPs.
www.biorxiv.org/content/10.6...
Selective Packaging of Rotavirus Double-Layered Particles into Host Microvesicles
Rotavirus is a non-enveloped RNA virus traditionally thought to exit host cells through lytic or conventional vesicular pathways, but recent evidence shows that it also exploits host microvesicles for...
www.biorxiv.org
September 20, 2026 at 2:37 PM
Selective Packaging of Rotavirus Double-Layered Particles into Host Microvesicles
RV infection strongly increases host microvesicle production, and these vesicles are enriched for DLPs even though the intracellular viral population is dominated by TLPs.
www.biorxiv.org/content/10.6...
RV infection strongly increases host microvesicle production, and these vesicles are enriched for DLPs even though the intracellular viral population is dominated by TLPs.
www.biorxiv.org/content/10.6...
Calpains orchestrate secretion of annexin-containing microvesicles during membrane repair, say Justin Krish Williams, Randy Schekman et al. @ucberkeleyofficial.bsky.social rupress.org/jcb/article/...
#EVs #Exosomes
#EVs #Exosomes
May 23, 2025 at 2:22 PM
Calpains orchestrate secretion of annexin-containing microvesicles during membrane repair, say Justin Krish Williams, Randy Schekman et al. @ucberkeleyofficial.bsky.social rupress.org/jcb/article/...
#EVs #Exosomes
#EVs #Exosomes
✨OLFM4 (cnt'd)✨
One study showed a complex relationship between EBV infection, OLFM4 & gastric cancer. OLFM4 was induced by EBV infection! OLFM4 is a target gene of the cGAS-STING pathway, and EBV infection activates that pathway, increasing OLFM4 expression. 🧪 🧵
www.nature.com/articles/s41...
One study showed a complex relationship between EBV infection, OLFM4 & gastric cancer. OLFM4 was induced by EBV infection! OLFM4 is a target gene of the cGAS-STING pathway, and EBV infection activates that pathway, increasing OLFM4 expression. 🧪 🧵
www.nature.com/articles/s41...
Epstein-Barr virus infection upregulates extracellular OLFM4 to activate YAP signaling during gastric cancer progression - Nature Communications
The functions of microvesicles (MVs) in gastric cancer are less studied compared to other types of extracellular vesicles. Here, the authors report that in Epstein-Barr virus (EBV)-associated gastric ...
www.nature.com
August 7, 2025 at 3:25 PM
✨OLFM4 (cnt'd)✨
One study showed a complex relationship between EBV infection, OLFM4 & gastric cancer. OLFM4 was induced by EBV infection! OLFM4 is a target gene of the cGAS-STING pathway, and EBV infection activates that pathway, increasing OLFM4 expression. 🧪 🧵
www.nature.com/articles/s41...
One study showed a complex relationship between EBV infection, OLFM4 & gastric cancer. OLFM4 was induced by EBV infection! OLFM4 is a target gene of the cGAS-STING pathway, and EBV infection activates that pathway, increasing OLFM4 expression. 🧪 🧵
www.nature.com/articles/s41...
Super excited my new review on midbody remnants (MBRs) is out:
"Condensates on the Move: Midbody Remnants as Large, Translation‐Competent Extracellular Vesicles"
#extracellularvesicles #midbody #mitosis #condensates #translation #proteinsynthesis
onlinelibrary.wiley.com/doi/10.1002/...
"Condensates on the Move: Midbody Remnants as Large, Translation‐Competent Extracellular Vesicles"
#extracellularvesicles #midbody #mitosis #condensates #translation #proteinsynthesis
onlinelibrary.wiley.com/doi/10.1002/...
Condensates on the Move: Midbody Remnants as Large, Translation‐Competent Extracellular Vesicles
Mitotic cells produce three EV types: exosomes and microvesicles (green/blue) delivering pre-formed molecules, and midbody remnants (magenta) containing functional ribosomes and translation machinery...
onlinelibrary.wiley.com
August 4, 2026 at 3:08 PM
Super excited my new review on midbody remnants (MBRs) is out:
"Condensates on the Move: Midbody Remnants as Large, Translation‐Competent Extracellular Vesicles"
#extracellularvesicles #midbody #mitosis #condensates #translation #proteinsynthesis
onlinelibrary.wiley.com/doi/10.1002/...
"Condensates on the Move: Midbody Remnants as Large, Translation‐Competent Extracellular Vesicles"
#extracellularvesicles #midbody #mitosis #condensates #translation #proteinsynthesis
onlinelibrary.wiley.com/doi/10.1002/...
If one painstakingly reads the titles of every ASAP article in JACS every month (as I do), one consistently finds cool dye/probes papers. Here are two standouts I found today. pubs.acs.org/doi/10.1021/...
(next in next post)
(next in next post)
Lipophilicity Modulation of Fluorescent Probes for In Situ Imaging of Cellular Microvesicle Dynamics
Real-time monitoring of dynamic microvesicles (MVs), vesicles associated with living cells, is of great significance in deeply understanding their origin, transport, and function. However, specific la...
pubs.acs.org
January 8, 2025 at 2:04 AM
If one painstakingly reads the titles of every ASAP article in JACS every month (as I do), one consistently finds cool dye/probes papers. Here are two standouts I found today. pubs.acs.org/doi/10.1021/...
(next in next post)
(next in next post)
Could an elevated level of salivary microvesicles be a biomarker for oral ulcers and cancer?
Discover new research findings: www.emjreviews.com/oncology/new...
Discover new research findings: www.emjreviews.com/oncology/new...
Elevated Salivary Microvesicles Linked to Oral Ulcers and Cancer
A study reveals that elevated salivary microvesicles could serve as biomarkers for non-healing oral ulcers and oral cancer.
https://www.emjreviews.com/oncology/news/elevated-salivary-microvesicles-linked-to-oral-ulcers-and-cancer/"
March 26, 2025 at 10:38 AM
Could an elevated level of salivary microvesicles be a biomarker for oral ulcers and cancer?
Discover new research findings: www.emjreviews.com/oncology/new...
Discover new research findings: www.emjreviews.com/oncology/new...
That one must have passed me by 🤔 (and as someone who published work on the similarities between influenza visions and microvesicles I now feel obscurely guilty...)
February 14, 2025 at 7:30 AM
That one must have passed me by 🤔 (and as someone who published work on the similarities between influenza visions and microvesicles I now feel obscurely guilty...)
Submissions now open for the Extracellular Vesicles & Immune Function topic—exosomes, microvesicles, immunomodulation, disease mechanisms & therapy.
Submit by May 2026: https://bit.ly/3YpmLRI
Submit by May 2026: https://bit.ly/3YpmLRI
January 8, 2026 at 10:34 AM
Submissions now open for the Extracellular Vesicles & Immune Function topic—exosomes, microvesicles, immunomodulation, disease mechanisms & therapy.
Submit by May 2026: https://bit.ly/3YpmLRI
Submit by May 2026: https://bit.ly/3YpmLRI
Happy #FluorescenceFriday ! Today is an exciting day because I can finally share data from my thesis work. Below is a gif of a blebbisome, a new large extracellular vesicle that I describe and characterize in the article below. www.nature.com/articles/s41...
Blebbisomes are large, organelle-rich extracellular vesicles with cell-like properties - Nature Cell Biology
Jeppesen, Sanchez et al. identify blebbisomes as large membrane-enclosed vesicles containing organelles and secreted by cells. Blebbisomes can both secrete and internalize exosomes and microvesicles.
www.nature.com
February 21, 2025 at 4:38 PM
Happy #FluorescenceFriday ! Today is an exciting day because I can finally share data from my thesis work. Below is a gif of a blebbisome, a new large extracellular vesicle that I describe and characterize in the article below. www.nature.com/articles/s41...
🧬 Could extracellular microvesicles help track rheumatoid arthritis activity? Anti-TNFα therapy reduced EMVs carrying disease-associated protein modifications, alongside improvements in disease activity, highlighting their potential as biomarkers. 🔬
🔗 vist.ly/5dybg
🔗 vist.ly/5dybg
Post-translational modifications in extracellular microvesicles from plasma of rheumatoid arthritis patients following anti-TNFα therapy
In RA patients anti-TNFa therapy significantly reduces the concentration of circulating EMVs.In RA patients anti TNFa therapy significantly reduces citrull
doi.org
August 7, 2026 at 3:26 PM
🧬 Could extracellular microvesicles help track rheumatoid arthritis activity? Anti-TNFα therapy reduced EMVs carrying disease-associated protein modifications, alongside improvements in disease activity, highlighting their potential as biomarkers. 🔬
🔗 vist.ly/5dybg
🔗 vist.ly/5dybg
The study reveals that platelet migration relies on precise integrin signaling, leading to the release of bioactive microvesicles. Congratulations to all authors on this new research in Blood Advances April 28, 2026. 2/2
@unc-brc.bsky.social @bloodjournals.hematology.org
@unc-brc.bsky.social @bloodjournals.hematology.org
May 1, 2026 at 1:37 PM
The study reveals that platelet migration relies on precise integrin signaling, leading to the release of bioactive microvesicles. Congratulations to all authors on this new research in Blood Advances April 28, 2026. 2/2
@unc-brc.bsky.social @bloodjournals.hematology.org
@unc-brc.bsky.social @bloodjournals.hematology.org
Circulating microvesicles (#MVs) may be associated with increased lactate dehydrogenase (#LDH) levels and clinical severity in patients with #SickleCellDisease (SCD).
Learn more: https://bit.ly/3JyF6Yx
#RareDisease #Microvesicles #LDHLevels #SickleCell #SCD #Hematology #MedSky
Learn more: https://bit.ly/3JyF6Yx
#RareDisease #Microvesicles #LDHLevels #SickleCell #SCD #Hematology #MedSky
Microvesicles May Serve as Markers of Complication Risk in SCD
An analysis of plasmatic MVs in patients with SCD discovered significantly higher levels of MVs in patients, linked to disease severity.
bit.ly
October 30, 2025 at 8:50 PM
Circulating microvesicles (#MVs) may be associated with increased lactate dehydrogenase (#LDH) levels and clinical severity in patients with #SickleCellDisease (SCD).
Learn more: https://bit.ly/3JyF6Yx
#RareDisease #Microvesicles #LDHLevels #SickleCell #SCD #Hematology #MedSky
Learn more: https://bit.ly/3JyF6Yx
#RareDisease #Microvesicles #LDHLevels #SickleCell #SCD #Hematology #MedSky
Structural Analysis of Membrane Proteins in Cell-Derived Microvesicles pubmed.ncbi.nlm.nih.gov/42681347/ #cryoem
September 3, 2026 at 5:01 PM
Structural Analysis of Membrane Proteins in Cell-Derived Microvesicles pubmed.ncbi.nlm.nih.gov/42681347/ #cryoem
Extracellular vesicles (EVs), including exosomes and microvesicles, emerge as pivotal tools in precision oncology due to their role in intercellular communication within cancer environments.
🔗 Source: https://pubmed.ncbi.nlm.nih.gov/42316572/
🔗 Source: https://pubmed.ncbi.nlm.nih.gov/42316572/
August 19, 2026 at 1:20 PM
Extracellular vesicles (EVs), including exosomes and microvesicles, emerge as pivotal tools in precision oncology due to their role in intercellular communication within cancer environments.
🔗 Source: https://pubmed.ncbi.nlm.nih.gov/42316572/
🔗 Source: https://pubmed.ncbi.nlm.nih.gov/42316572/
RRID:AB_955238 was used by the authors of the BMC Biotechnology paper "Microvesicles-delivering Smad7 have advantages over microvesicles in suppressing fibroblast differentiation in a model of Peyronie’s diseas…". RRIDs like this improve reproducibility in scientific research. #OpenScience
doi.org
March 7, 2025 at 8:01 AM
RRID:AB_955238 was used by the authors of the BMC Biotechnology paper "Microvesicles-delivering Smad7 have advantages over microvesicles in suppressing fibroblast differentiation in a model of Peyronie’s diseas…". RRIDs like this improve reproducibility in scientific research. #OpenScience