##PseudomonasAeruginosa
Our latest work is out in @natcomms.nature.com!

Clinical adaptation of #PseudomonasAeruginosa can drive pyruvate secretion, where it scavenges ROS, dampens immune activation and promotes persistence, highlighting bacterial metabolism as an active player in infection🦠

www.nature.com/articles/s41...
Immune protection and persistence in Pseudomonas aeruginosa infections by pyruvate cross-feeding - Nature Communications
The study shows that metabolic mutations in Pseudomonas aeruginosa lead to pyruvate secretion, which reduces oxidative stress, dampens immune responses, promoting bacterial survival and persistence in...
www.nature.com
July 9, 2026 at 8:15 AM
Resistance variation and bacterial interactions shape adaptation of a genetically diverse pathogen population to antibiotic therapy
#Pseudomonasaeruginosa

#ISMEJournal from @schulenburglab.bsky.social

academic.oup.com/ismej/advanc...
Resistance variation and bacterial interactions shape adaptation of a genetically diverse pathogen population to antibiotic therapy
Abstract. Antimicrobial resistance poses a major threat to global human health. The emergence and spread of antimicrobial resistance is usually studied for
academic.oup.com
February 27, 2026 at 1:07 PM
The 1.3 Å resolution crystal structure of the N-terminally truncated type IV pilin from Pseudomonas aeruginosa strain P1 is the first to be reported from this group @yorkuniversity @IUCr #TypeIVPilins #PseudomonasAeruginosa #AIGeneratedModels doi.org/10.1107/S205...
December 18, 2024 at 3:04 PM
New research by Dr. Kari Mergenhagen shows that climate zones influence the prevalence of #Pseudomonasaeruginosa in diabetic foot infections, with hot, humid areas seeing higher infection rates. #IDshy #MEDsky #AntibioticResistance #ClimateHealth

Read more: www.contagionlive.com/view/climate...
Climate Zones Impact Prevalence of Pseudomonas Aeruginosa in Diabetic Foot Infections
P aeruginosa is found in 11.6% of diabetic foot infection cultures from hot, humid climates.
www.contagionlive.com
December 13, 2024 at 2:19 PM
The histidine kinase NahK regulates pyocyanin production through the PQS system
#Pseudomonasaeruginosa

-in J Bacteriology from Elizabeth M. Boon
with @laahrs.bsky.social

journals.asm.org/doi/10.1128/...
January 4, 2024 at 9:37 AM
The incubator smells like grapes. #IYKYK #Pseudomonasaeruginosa
March 27, 2025 at 7:15 PM
July 2, 2026 at 2:42 PM
#Medsky🧪 #IDsky #pharmasky The SOS response is among the most conserved pathways that promote the acquisition of #antibioticresistance in bacteria.This study aimed to identify and characterize small-molecule inhibitors of the SOS response system in the opportunistic pathogen #Pseudomonasaeruginosa.
Identification and characterization of a small-molecule inhibitor of the Pseudomonas aeruginosa SOS response https://www.biorxiv.org/content/10.1101/2025.05.13.651886v1
May 16, 2025 at 5:03 AM
Cientistas descobriram que a superbactéria Pseudomonas aeruginosa consegue se alimentar de plásticos usados em hospitais.

Matéria completa - regisandrade.com.br/superbacteri...

#superbactéria #pseudomonasaeruginosa #hospital #infecçãoshospitalares #resistênciaaosantibióticos #plásticobiodegradável
July 21, 2025 at 11:23 PM
4➡️Un article original tentant d’évaluer la sensibilité du #ceftolozane/tazobactam et des comparateurs aux isolats de Pseudomonas aeruginosa prélevés lors de cas d'infections des voies respiratoires.

www.sciencedirect.com/science/arti...

#IDSky #IDSkyFr #PseudomonasAeruginosa #SMARTstudy
September 1, 2025 at 8:12 AM
[Publication] The article "In vitro susceptibility of ciprofloxacin-resistant strains of #PseudomonasAeruginosa to high concentration ciprofloxacin-containing ototopical solution" is now available.

www.sciencedirect.com/science/arti...

#IDsky #AcuteOtitisExterna #AntibioticResistance
In vitro susceptibility of ciprofloxacin-resistant strains of Pseudomonas aeruginosa to high concentration ciprofloxacin-containing ototopical solution
Pseudomonas aeruginosa is the most frequently isolated pathogen in acute otitis externa (AOE), with ototopical antibiotics being the mainstay of treat…
www.sciencedirect.com
July 21, 2025 at 7:20 AM
The structure of a chimeric efflux pump was determined by cryoEM under apo and kanamycin-supplemented conditions and adopted symmetric-like and asymmetric conformations #PseudomonasAeruginosa #DrugEffluxTransporters #MembraneProteins doi.org/10.1107/S205...
March 18, 2026 at 3:51 PM
#AntibioticResistance demands smarter solutions.

This study identifies Medicarpin 3-O-glucoside as a promising inhibitor of #PseudomonasAeruginosa, paving the way for new therapies against drug-resistant infections. #MolecularDynamicsSimulations

#OpenChemistry: doi.org/10.1515/chem...
August 1, 2026 at 4:45 AM
🧬 From oxidative stress and cell viability to drug-metabolizing enzymes, this study provides a comprehensive assessment of the safety and antimicrobial potential of the furin inhibitors MI-1851 and MI-2415. #PseudomonasAeruginosa #CytochromeP450
www.mdpi.com/2227-9059/12...
September 22, 2026 at 1:35 AM
The DUF2875 domain-containing T6SS adaptor protein Tla3 from Pseudomonas aeruginosa strain UCBPP-PA14 shows a thiolase-like fold, marked by a five-layered α–β–α–β–α core topology #T6SS #Adaptors #PseudomonasAeruginosa doi.org/10.1107/S205...
August 11, 2026 at 1:53 PM
#PublicaSalutIB @idisba.bsky.social i Microbiologia de Son espases han publicat un estudi sobre l'ús d'un dispositiu en paper per detectar nivells de P. aeruginosa en esput https://www.infosalut.com/17344 https://doi.org/10.1016/j.bios.2024.117097 

#pseudomonasaeruginosa #dispositiuenpaper
May 15, 2025 at 10:16 AM
#PublicaSalutIB Microbiologia de Son Espases i @idisba.bsky.social  han participat en la descripció de la resistència a infecció fàgica en P. aeruginosa i presència de fags Pf https://www.infosalut.com/17303 https://doi.org/10.1128/spectrum.03010-24

#pseudomonasaeruginosa #microbiologia
April 21, 2025 at 11:44 AM
[Publication] The article "Evolution of the inappropriate use of broad-spectrum antibiotics for #PseudomonasAeruginosa infections following the 2022 CA-SFM guidelines" is now available.

www.sciencedirect.com/science/arti...

#IDsky #AntimicrobialSusceptibilityTesting #AntimicrobialStewardship
Evolution of the inappropriate use of broad-spectrum antibiotics for Pseudomonas aeruginosa infections following the 2022 CA-SFM guidelines
The European Committee on Antimicrobial Susceptibility Testing (EUCAST) changed the definition of the ‘intermediate’ (I) category in 2019, now defined…
www.sciencedirect.com
October 15, 2025 at 7:19 AM
Does E. coli truly represent all bacterial persistence? Princeton’s Leon and Brynildsen's research in reveals that Pseudomonas aeruginosa follows different rules.
go.njmicrobe.org/dOdEyv #Microbiology #AntibioticResistance #PseudomonasAeruginosa #Research #EColi
Beyond the E. coli Paradigm: Why Pseudomonas Persistence Follows Its Own Rules
For decades, the study of bacterial persistence has relied heavily on Escherichia coli as the primary model organism. Microbiologists have largely operated under the assumption that the mechanisms gov...
go.njmicrobe.org
December 22, 2025 at 6:45 PM