Der 3D-Drucker-Hersteller UltiMaker und das Medizintechnik-Startup Bioactivx aus Singapur wollen gemeinsam ein Drucksystem für die Wundversorgung entwickeln. Es soll die Produkte bei Bedarf nahe am Behandlungsort herstellen. Beide Firmen haben dazu eine Absichtserklärung unterzeichnet. Bioactivx meldet zugleich zwei Schritte: Das Unternehmen hat eine eigene Filamentproduktion samt Druckfarm im Reinraum eröffnet. Zudem hat die singapurische Gesundheitsbehörde […] Der Beitrag UltiMaker und Bioactivx planen Wundversorgung aus dem 3D-Drucker vor Ort erschien zuerst auf 3Druck.com - The Independent AM Magazine.

(NaturalNews) A recent narrative review published in Frontiers in Nutrition reports that the health benefits of fermented foods stem from a complex network of bioac...

Durik et al. show that senescent cells generate fragments, termed SCAFs, that support survival by shedding damaged intracellular material. SCAF rupture releases DAMPs, amyloid-like proteins, and bioac...

Edible Garden (Nasdaq: EDBL) and agricultural innovation company Square Roots announced a strategic product development partnership to create next-generation, clean-label functional ready-to-drink beverages. The collaboration combines Square Roots' controlled-environment agriculture and plant science capabilities with Edible Garden's Farm-to-Formula® platform and Tetra Pak® aseptic manufacturing.Square Roots will identify and cultivate nutrient-dense crops optimized for naturally occurring bioactive compounds, while Edible Garden will convert these into premium functional beverages. Initial concepts are expected to target cognitive wellness, metabolic health, healthy aging, GLP-1 support and performance nutrition, with future commercialization supported by Edible Garden's Prairie Hills facility in Iowa.

Animal sounds can be recorded and analysed to help to derive ecological insight and inform conservation decision-making. In this Review, Perea, Burivalova and colleagues outline how conservation bioac...

Lake Greifensee is periodically affected by cyanobacterial blooms and associated cyanotoxins20,21,22 (Fig. 1). Our study focuses on two key groups: the toxic Microcystaceae group (Microcystis spp., Aphanothece spp., Aphanocapsa spp.) and Dolichospermum spp. Microcystacae are the most common potentially toxic bloom-forming cyanobacteria worldwide23, typically blooming in Greifensee during summer and autumn (Fig. 1c). Previous studies confirm the production of microcystins and numerous other bioactive metabolites from this group in the lake, including during our study period20,22. Dolichospermum, the second most common potentially toxic bloom-forming cyanobacterium globally, is known to produce both hepatotoxins and neurotoxins3,24. While rarely forming surface blooms in Greifensee, it reaches peak abundance in late summer, and bioactive metabolites potentially associated with this taxon are found during the study period22. Our high-resolution data reveal significant temporal fluctuations in both cyanobacteria (Fig. 1c). This provides a unique opportunity to examine growth dynamics and their relationships with biotic and abiotic factors at temporal scales directly relevant to bloom formation. To quantify these dynamics and investigate the influence of biotic interactions, we present an nGR analysis based on high-frequency monitoring data. To estimate daily nGRs, we calculate the difference in the natural logarithm of taxon densities for each taxon between consecutive...

Global Bioactive Ingredients market size is expected to reach $78.81 billion by 2030 at 8.8%, organic and natural ingredient adoption fuels growth in bioactive ingredients market

Wine-making acid helps scientists separate cobalt and nickel from battery waste using electrowinning technology.

The bioactive wound care market is projected to reach $12.48 by 2030 at 8.5%, driven by chronic disease prevalence, advanced dressings, smart wound monitoring, and hydrogel innovations.

From the spice rack to the lab bench, emerging proteomic insights reveal how hidden peptide fragments in everyday spices may shape the next generation of functional foods.

200 mg EGCg / 80% Catechins Supports Cellular Health* One capsule of NOW® Green Tea Extract with 200 mg EGCg possesses the phytonutrient content equal to about 2-3 cups of green tea. Green tea’s bioac...

American elderberry (Sambucus nigra subsp. canadensis) is recognized as a rich source of bioactive compounds with nutritional and therapeutic potential. However, comprehensive quantification of its metabolites remains analytically challenging due to the structural complexity of phenolics and matrix interferences in juice extracts. In this study, a targeted ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) workflow was developed and validated to quantify 22 bioactive metabolites, including anthocyanins, flavonoids, and phenolic acids, in juices from 21 American elderberry cultivars. An optimized UHPLC-MS/MS system demonstrated higher sensitivity, selectivity, and throughput than conventional high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS), achieving limits of detection and quantification below 0.1 ng/mL for most analytes. Matrix effects were effectively mitigated through sample dilution, enabling accurate and reproducible quantification across complex juice matrices. Quantification of metabolites showed that accession 1199 exhibited high levels of cyanidin-based anthocyanins, suggesting its utility as a natural food color source. Overall, high-throughput UHPLC-MS/MS method provides a robust analytical framework for metabolomic profiling for cultivar selection and the development of elderberry-derived functional products.

The global effort to eradicate malaria requires the development of drugs with novel mechanisms of action and differentiated pharmacological profiles. Both liver and blood phases of Plasmodium infection are essential for disease progression and transmission, making them primary targets for therapeutic intervention. In this study, we established a dual-luciferase reporter assay to simultaneously assess Plasmodium berghei liver-stage development and host cell viability. Screening a library of bioactive small molecules with annotated human targets revealed several inhibitors with potent liver-stage activity and minimal cytotoxicity. Further profiling against P. falciparum asexual blood stages identified compounds with dual-stage activity, underscoring their potential utility for development as either prophylactic or therapeutic agents. Knowledge of their human targets will facilitate investigation into host- or parasite-directed antimalarial mechanisms, thereby accelerating both biological insight and rational drug development. Our findings constitute a valuable resource for research on malaria biology and the discovery of next-generation antimalarials.

The global effort to eradicate malaria requires the development of drugs with novel mechanisms of action and differentiated pharmacological profiles. Both liver and blood phases of Plasmodium infection are essential for disease progression and transmission, making them primary targets for therapeutic intervention. In this study, we established a dual-luciferase reporter assay to simultaneously assess Plasmodium berghei liver-stage development and host cell viability. Screening a library of bioactive small molecules with annotated human targets revealed several inhibitors with potent liver-stage activity and minimal cytotoxicity. Further profiling against P. falciparum asexual blood stages identified compounds with dual-stage activity, underscoring their potential utility for development as either prophylactic or therapeutic agents. Knowledge of their human targets will facilitate investigation into host- or parasite-directed antimalarial mechanisms, thereby accelerating both biological insight and rational drug development. Our findings constitute a valuable resource for research on malaria biology and the discovery of next-generation antimalarials.

Bioacoustic Data Analysis (BIAC05) equips researchers with the skills to analyse animal acoustic signals in R. Covering spectrograms, signal structure, annotation workflows, and acoustic diversity met...

An innovative approach combining electrochemistry with online quadrupole time-of-flight-mass spectrometry (EC-MS/MS) was employed to study the oxidative products and metabolic pathways of three bioac...

Bioacoustic Data Analysis (BIAC05) equips researchers with the skills to analyse animal acoustic signals in R. Covering spectrograms, signal structure, annotation workflows, and acoustic diversity met...

Extra-virgin olive oil (EVOO), a popular functional food and major source of fat in the Mediterranean diet, possesses a variety of healthful components, including monounsaturated fatty acids and bioac...

Traditional wound care methods have limitations, highlighting the need for advanced bioactive dressings that enhance healing and reduce infection risks.