We’re excited to announce the opening of the Geneva Expansion Microscopy Facility (GenExM)!
GenExM is a full-service U-ExM platform (U-ExM, Cryo-ExM, iU-ExM), delivering nanoscale imaging.
Led by Dr. Olivier Mercey, GenExM welcomes academic & industrial collaborations.
👉 www.unige.ch/genexm/
GenExM is a full-service U-ExM platform (U-ExM, Cryo-ExM, iU-ExM), delivering nanoscale imaging.
Led by Dr. Olivier Mercey, GenExM welcomes academic & industrial collaborations.
👉 www.unige.ch/genexm/
December 10, 2025 at 8:43 PM
We’re excited to announce the opening of the Geneva Expansion Microscopy Facility (GenExM)!
GenExM is a full-service U-ExM platform (U-ExM, Cryo-ExM, iU-ExM), delivering nanoscale imaging.
Led by Dr. Olivier Mercey, GenExM welcomes academic & industrial collaborations.
👉 www.unige.ch/genexm/
GenExM is a full-service U-ExM platform (U-ExM, Cryo-ExM, iU-ExM), delivering nanoscale imaging.
Led by Dr. Olivier Mercey, GenExM welcomes academic & industrial collaborations.
👉 www.unige.ch/genexm/
Trouble imaging actin in ExM? Meet HAK-Actin, a probe for U-ExM, cryo-ExM & iU-ExM. Enables post-expansion labeling for max signal. www.biorxiv.org/content/10.1...
Soon at @spirochrome.com
Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social
Soon at @spirochrome.com
Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social
August 28, 2025 at 7:03 AM
Trouble imaging actin in ExM? Meet HAK-Actin, a probe for U-ExM, cryo-ExM & iU-ExM. Enables post-expansion labeling for max signal. www.biorxiv.org/content/10.1...
Soon at @spirochrome.com
Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social
Soon at @spirochrome.com
Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social
The first paper of my PostDoc in Christa Schlepers group (@archaea-vienna.bsky.social) on the dynamics of Asgard archaea is now out in Nature!
www.nature.com/articles/s41...
This was a great team effort and I am looking forward to uncover the complex behavior of these cells further!
www.nature.com/articles/s41...
This was a great team effort and I am looking forward to uncover the complex behavior of these cells further!
Dynamic protrusions mediate crawling motility in Asgard archaea - Nature
Anoxic live-cell imaging shows actin-dependent crawling motility and dynamic protrusions in Asgard archaea, providing insights into cellular innovations that may have contributed to eukaryotic evoluti...
www.nature.com
October 1, 2026 at 9:20 AM
#FluorescenceFriday: getting ready for #GEF25, playing with Ciarán's stunning ExM data
September 26, 2025 at 11:48 AM
#FluorescenceFriday: getting ready for #GEF25, playing with Ciarán's stunning ExM data
The MIT McGovern Institute’s story celebrating the 10th birthday of expansion microscopy (ExM). One highlight: ExM is not only easy to do, it’s easy to modify - so lots of people are altering and applying ExM for custom purposes, leading to unexpected innovations: mcgovern.mit.edu/2025/03/03/t...
March 10, 2025 at 12:20 PM
The MIT McGovern Institute’s story celebrating the 10th birthday of expansion microscopy (ExM). One highlight: ExM is not only easy to do, it’s easy to modify - so lots of people are altering and applying ExM for custom purposes, leading to unexpected innovations: mcgovern.mit.edu/2025/03/03/t...
Our new paper in @plosbiology.org introduces IntAct-U-ExM enabling isoform-specific imaging of actin at nanoscale across yeast, mammalian cells & primary neurons. Fabulous work spearheaded by
@anubhavdhar.bsky.social along with an amazing team! #actin #U-ExM journals.plos.org/plosbiology/...
@anubhavdhar.bsky.social along with an amazing team! #actin #U-ExM journals.plos.org/plosbiology/...
June 12, 2026 at 7:34 PM
Our new paper in @plosbiology.org introduces IntAct-U-ExM enabling isoform-specific imaging of actin at nanoscale across yeast, mammalian cells & primary neurons. Fabulous work spearheaded by
@anubhavdhar.bsky.social along with an amazing team! #actin #U-ExM journals.plos.org/plosbiology/...
@anubhavdhar.bsky.social along with an amazing team! #actin #U-ExM journals.plos.org/plosbiology/...
My favorite quote from Nature's 10 year retrospective on expansion microscopy (ExM): “It’s so easy, even my nine-year-old can do it,” [CMU professor, SynthNeuro group alum, and ExM innovator, Yongxin] Zhao says. Happy 10th birthday, expansion microscopy!
A decade in, expansion microscopy is unlocking insights across biology and medicine
https://go.nature.com/4adlNgg
https://go.nature.com/4adlNgg
‘Expansion microscopy’ turns ten: how a tissue-swelling method brought super-resolution imaging to the masses
A decade in, expansion microscopy is unlocking insights across biology and medicine.
go.nature.com
January 13, 2025 at 11:18 PM
My favorite quote from Nature's 10 year retrospective on expansion microscopy (ExM): “It’s so easy, even my nine-year-old can do it,” [CMU professor, SynthNeuro group alum, and ExM innovator, Yongxin] Zhao says. Happy 10th birthday, expansion microscopy!
Our collaboration with @mbonhivers.bsky.social is now out in @plosbiology.org! 🎉Using U-ExM, we mapped the formation of the flagellar pocket collar in T. brucei. Huge thanks to everyone involved — one step closer to #PhDone!
#ExM #oneringtorulethemall #Bilbo1 #trypanosoma #protistsonsky
#ExM #oneringtorulethemall #Bilbo1 #trypanosoma #protistsonsky
The flagellar pocket collar (FPC) is a cytoskeletal structure essential for nutrient uptake & immune evasion in #Trypanosome. @mbonhivers.bsky.social &co use U-ExM to provide novel insights into FPC biogenesis, and reveal 2 unknown cytoskeletal structures @plosbiology.org 🧪 plos.io/4n3bWi6
October 10, 2025 at 6:47 PM
Our collaboration with @mbonhivers.bsky.social is now out in @plosbiology.org! 🎉Using U-ExM, we mapped the formation of the flagellar pocket collar in T. brucei. Huge thanks to everyone involved — one step closer to #PhDone!
#ExM #oneringtorulethemall #Bilbo1 #trypanosoma #protistsonsky
#ExM #oneringtorulethemall #Bilbo1 #trypanosoma #protistsonsky
Isadonna Tengganu and Ke Hu develop transfection and ExM protocols for Chromera velia, enabling direct comparisons with its parasitic apicomplexan relative, Toxoplasma gondi.
journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
January 13, 2026 at 9:53 AM
Isadonna Tengganu and Ke Hu develop transfection and ExM protocols for Chromera velia, enabling direct comparisons with its parasitic apicomplexan relative, Toxoplasma gondi.
journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
Exciting news! Our @erc.europa.eu StG project ARCHAEAOLOGY got funded 🎉
We’ll combine cryoET/EM, ExM & spatial omics to explore the subcellular organization of Asgard archaea.
Job ads coming soon! 🦠 ❄️ 🔬
#TeamTomo #ArchaeaSky #MicroSky
We’ll combine cryoET/EM, ExM & spatial omics to explore the subcellular organization of Asgard archaea.
Job ads coming soon! 🦠 ❄️ 🔬
#TeamTomo #ArchaeaSky #MicroSky
Congratulations to @florianwollweber.bsky.social, the recently appointed Group Leader at EMBL Grenoble, who received an ERC Starting Grant worth approximately €2 million to investigate the origins of eukaryotic cell complexity.
bit.ly/4gNwEBk
bit.ly/4gNwEBk
September 5, 2026 at 12:57 PM
Exciting news! Our @erc.europa.eu StG project ARCHAEAOLOGY got funded 🎉
We’ll combine cryoET/EM, ExM & spatial omics to explore the subcellular organization of Asgard archaea.
Job ads coming soon! 🦠 ❄️ 🔬
#TeamTomo #ArchaeaSky #MicroSky
We’ll combine cryoET/EM, ExM & spatial omics to explore the subcellular organization of Asgard archaea.
Job ads coming soon! 🦠 ❄️ 🔬
#TeamTomo #ArchaeaSky #MicroSky
The ExM gang @jvermot.bsky.social @mahjoublab.bsky.social @marinelap.bsky.social @centriolelab.bsky.social @simonemortal.bsky.social et al #GEF25
September 29, 2025 at 8:04 PM
One of this morning's talks is @kevin-dean.bsky.social explaining how to do cyclic IF for ExM
#I2KxBINA
#I2KxBINA
September 30, 2026 at 3:11 PM
One of this morning's talks is @kevin-dean.bsky.social explaining how to do cyclic IF for ExM
#I2KxBINA
#I2KxBINA
We are growing! A new @zeiss-microscopy.bsky.social widefield tailored for ExM- supported by @moorefound.bsky.social is settling! Another one is on its way at @gautamdey.bsky.social Lab !
These two will become the powerhorses for high-througput imaging of the ExM Atlas of #Microbial Eukaryote !
These two will become the powerhorses for high-througput imaging of the ExM Atlas of #Microbial Eukaryote !
July 17, 2025 at 12:01 PM
We are growing! A new @zeiss-microscopy.bsky.social widefield tailored for ExM- supported by @moorefound.bsky.social is settling! Another one is on its way at @gautamdey.bsky.social Lab !
These two will become the powerhorses for high-througput imaging of the ExM Atlas of #Microbial Eukaryote !
These two will become the powerhorses for high-througput imaging of the ExM Atlas of #Microbial Eukaryote !
More #ExM fun in the lab today. This is Hexamita #protistsonsky
May 9, 2025 at 4:06 PM
More #ExM fun in the lab today. This is Hexamita #protistsonsky
Happy #FluorescenceFriday all!
Checkout these beautiful basal bodies in airway #multiciliated cells expanded via U-ExM 😍
Images captured by the super talented @maneesha07.bsky.social on a #Nikon NSPARC 🔬.
Checkout these beautiful basal bodies in airway #multiciliated cells expanded via U-ExM 😍
Images captured by the super talented @maneesha07.bsky.social on a #Nikon NSPARC 🔬.
March 13, 2026 at 4:41 PM
Happy #FluorescenceFriday all!
Checkout these beautiful basal bodies in airway #multiciliated cells expanded via U-ExM 😍
Images captured by the super talented @maneesha07.bsky.social on a #Nikon NSPARC 🔬.
Checkout these beautiful basal bodies in airway #multiciliated cells expanded via U-ExM 😍
Images captured by the super talented @maneesha07.bsky.social on a #Nikon NSPARC 🔬.
Exciting day for the lab: our 1rst paper is officially out in @currentbiology.bsky.social 🥳 Wonderful collaboration wt @gautamdey.bsky.social showing how Cryo-ExM achieves consistent immunostaining in diverse diatoms, from the lab and the natural environment 1/n
#ProtistsOnSky
tinyurl.com/2zxaund7
#ProtistsOnSky
tinyurl.com/2zxaund7
October 31, 2025 at 3:27 PM
Exciting day for the lab: our 1rst paper is officially out in @currentbiology.bsky.social 🥳 Wonderful collaboration wt @gautamdey.bsky.social showing how Cryo-ExM achieves consistent immunostaining in diverse diatoms, from the lab and the natural environment 1/n
#ProtistsOnSky
tinyurl.com/2zxaund7
#ProtistsOnSky
tinyurl.com/2zxaund7
Thank you @mollyherring.bsky.social for the stunning showcase 😍
Like what you see? Come ExM with us! Let’s flood the internet with microbial marvels 🦠
#ProtistsOnSky #MicroEvoSky 🧪🔬🌍
@dudinlab.bsky.social @centriolelab.bsky.social @moorefound.bsky.social @embl.org @erc.europa.eu @embo.org
Like what you see? Come ExM with us! Let’s flood the internet with microbial marvels 🦠
#ProtistsOnSky #MicroEvoSky 🧪🔬🌍
@dudinlab.bsky.social @centriolelab.bsky.social @moorefound.bsky.social @embl.org @erc.europa.eu @embo.org
February 4, 2026 at 8:43 PM
Thank you @mollyherring.bsky.social for the stunning showcase 😍
Like what you see? Come ExM with us! Let’s flood the internet with microbial marvels 🦠
#ProtistsOnSky #MicroEvoSky 🧪🔬🌍
@dudinlab.bsky.social @centriolelab.bsky.social @moorefound.bsky.social @embl.org @erc.europa.eu @embo.org
Like what you see? Come ExM with us! Let’s flood the internet with microbial marvels 🦠
#ProtistsOnSky #MicroEvoSky 🧪🔬🌍
@dudinlab.bsky.social @centriolelab.bsky.social @moorefound.bsky.social @embl.org @erc.europa.eu @embo.org
A super detailed protocol + video on Cryo-ExM - Cryo-Expansion Microscopy, led by the labs of our former postdocs @marinelap.bsky.social & @ebertiaux.bsky.social.
Clear, practical, and very useful for anyone doing nanoscale imaging 🚀 app.jove.com/t/68595/expa...
Clear, practical, and very useful for anyone doing nanoscale imaging 🚀 app.jove.com/t/68595/expa...
December 25, 2025 at 1:41 PM
A super detailed protocol + video on Cryo-ExM - Cryo-Expansion Microscopy, led by the labs of our former postdocs @marinelap.bsky.social & @ebertiaux.bsky.social.
Clear, practical, and very useful for anyone doing nanoscale imaging 🚀 app.jove.com/t/68595/expa...
Clear, practical, and very useful for anyone doing nanoscale imaging 🚀 app.jove.com/t/68595/expa...
Happy #FluorescenceFriday all! 🔬
First Chlamydomonas experiment/U-ExM image from my lab. Haven't worked on these beautiful little cells since grad school 😍 #memories #cilia
First Chlamydomonas experiment/U-ExM image from my lab. Haven't worked on these beautiful little cells since grad school 😍 #memories #cilia
May 1, 2026 at 2:31 PM
Happy #FluorescenceFriday all! 🔬
First Chlamydomonas experiment/U-ExM image from my lab. Haven't worked on these beautiful little cells since grad school 😍 #memories #cilia
First Chlamydomonas experiment/U-ExM image from my lab. Haven't worked on these beautiful little cells since grad school 😍 #memories #cilia
I am excited to share our most recent work collaborating with @centriolelab.bsky.social and @stearnslab.bsky.social to look at the ciliary base of mammalian multiciliated cells w/ cryo-ET, XL/MS, and U-ExM www.biorxiv.org/content/10.6...
April 8, 2026 at 6:25 AM
I am excited to share our most recent work collaborating with @centriolelab.bsky.social and @stearnslab.bsky.social to look at the ciliary base of mammalian multiciliated cells w/ cryo-ET, XL/MS, and U-ExM www.biorxiv.org/content/10.6...
July 3, 2025 at 8:05 AM
🔬🔦Our Imaging spotlight from @hiralshah.bsky.social & team highlights their U-ExM atlas of planktonic eukaryotes, including details on how you can explore this wonderful resource. Plus, check out Hiral’s top tips on getting started with expansion microscopy.
focalplane.biologists.com/2026/01/20/i...
focalplane.biologists.com/2026/01/20/i...
Imaging spotlight: U-ExM atlas of microbial eukaryotes - FocalPlane
Imaging spotlight: U-ExM atlas of microbial eukaryotes - News
focalplane.biologists.com
January 20, 2026 at 1:26 PM
🔬🔦Our Imaging spotlight from @hiralshah.bsky.social & team highlights their U-ExM atlas of planktonic eukaryotes, including details on how you can explore this wonderful resource. Plus, check out Hiral’s top tips on getting started with expansion microscopy.
focalplane.biologists.com/2026/01/20/i...
focalplane.biologists.com/2026/01/20/i...