Traver Hart’s team evaluated a 77,000 dual-gRNA Cas12a library on bioRxiv, revealing that dual-target locus excision operates at very low efficiency in mammalian screens due to asynchronous cleavage dynamics. 🧬🤖
#CRISPR #Cas12a #bioRxiv2026 #MDAnderson #GeneEditing #FunctionalGenomics
#CRISPR #Cas12a #bioRxiv2026 #MDAnderson #GeneEditing #FunctionalGenomics
September 28, 2026 at 9:19 AM
Traver Hart’s team evaluated a 77,000 dual-gRNA Cas12a library on bioRxiv, revealing that dual-target locus excision operates at very low efficiency in mammalian screens due to asynchronous cleavage dynamics. 🧬🤖
#CRISPR #Cas12a #bioRxiv2026 #MDAnderson #GeneEditing #FunctionalGenomics
#CRISPR #Cas12a #bioRxiv2026 #MDAnderson #GeneEditing #FunctionalGenomics
#TropicalPlants
Functional genomics identifies candidate genes regulating important traits in tropical plant species
Details: https://maxapress.com/article/doi/10.48130/tp-0026-0016
#FunctionalGenomics #PlantGenetics
Functional genomics identifies candidate genes regulating important traits in tropical plant species
Details: https://maxapress.com/article/doi/10.48130/tp-0026-0016
#FunctionalGenomics #PlantGenetics
September 25, 2026 at 4:19 AM
#TropicalPlants
Functional genomics identifies candidate genes regulating important traits in tropical plant species
Details: https://maxapress.com/article/doi/10.48130/tp-0026-0016
#FunctionalGenomics #PlantGenetics
Functional genomics identifies candidate genes regulating important traits in tropical plant species
Details: https://maxapress.com/article/doi/10.48130/tp-0026-0016
#FunctionalGenomics #PlantGenetics
Before you pick a cell line, ask where the target actually matters. Disease Atlas reads CRISPR knockout screens by lineage: KRAS is a hard dependency in pancreatic and colorectal models, barely registers in brain or kidney. That gradient picks your model. #FunctionalGenomics
September 1, 2026 at 3:32 PM
Before you pick a cell line, ask where the target actually matters. Disease Atlas reads CRISPR knockout screens by lineage: KRAS is a hard dependency in pancreatic and colorectal models, barely registers in brain or kidney. That gradient picks your model. #FunctionalGenomics
Institut Micalis is hiring:
Postdoctoral Position in Functional Genomics: Analysis of Human Diseases Using Fish Models
#postdoc #biology #functionalgenomics
Postdoctoral Position in Functional Genomics: Analysis of Human Diseases Using Fish Models
#postdoc #biology #functionalgenomics
August 28, 2026 at 2:30 AM
The University of Manchester (@manchester.ac.uk) is hiring:
Bioinformatics Research Associate
#postdoc #biology #functionalgenomics
Bioinformatics Research Associate
#postdoc #biology #functionalgenomics
August 21, 2026 at 1:59 AM
The University of Manchester (@manchester.ac.uk) is hiring:
Bioinformatics Research Associate
#postdoc #biology #functionalgenomics
Bioinformatics Research Associate
#postdoc #biology #functionalgenomics
The strongest evidence a gene matters is what happens when you switch it off. Disease Atlas pulls the perturbation evidence for a target into one view: CRISPR, RNAi, over-expression, and what each did to the phenotype. The functional layer, next to the genetics. #FunctionalGenomics
August 18, 2026 at 7:03 AM
The strongest evidence a gene matters is what happens when you switch it off. Disease Atlas pulls the perturbation evidence for a target into one view: CRISPR, RNAi, over-expression, and what each did to the phenotype. The functional layer, next to the genetics. #FunctionalGenomics
#ERGAReads | 🌿 Plant genome information facilitates plant functional genomics link.springer.com/article/10.1...
#plant #plantgenomes #genomics #functionalgenomics #science #article #review
#plant #plantgenomes #genomics #functionalgenomics #science #article #review
Plant genome information facilitates plant functional genomics - Planta
Main conclusion In this review, we give an overview of plant sequencing efforts and how this impacts plant functional genomics research. Abstract Plant genome sequence information greatly facilitates…
link.springer.com
August 12, 2026 at 8:01 AM
#ERGAReads | 🌿 Plant genome information facilitates plant functional genomics link.springer.com/article/10.1...
#plant #plantgenomes #genomics #functionalgenomics #science #article #review
#plant #plantgenomes #genomics #functionalgenomics #science #article #review
The final version is now online! #RNALocalization #Chromatin #FunctionalGenomics #CellMigration #CancerBiology www.nature.com/articles/s41...
August 11, 2026 at 9:13 PM
The final version is now online! #RNALocalization #Chromatin #FunctionalGenomics #CellMigration #CancerBiology www.nature.com/articles/s41...
Ghent University (@ds-ugent.bsky.social) is hiring:
Postdoctoral Scientist in Cell Engineering and Functional Genomics
#postdoc #functionalgenomics #biomedicalsciences
Postdoctoral Scientist in Cell Engineering and Functional Genomics
#postdoc #functionalgenomics #biomedicalsciences
August 6, 2026 at 12:07 AM
Universite de Strasbourg is hiring:
Postdoctoral Research Fellow in Functional Genomics and Molecular Mechanisms of Oncogenic Transcription Factor Fusions
#postdoc #biology #functionalgenomics
Postdoctoral Research Fellow in Functional Genomics and Molecular Mechanisms of Oncogenic Transcription Factor Fusions
#postdoc #biology #functionalgenomics
July 21, 2026 at 2:17 AM
A Zhongshuang 11 rapeseed CRISPR mutant library provides a ready resource for functional genomics and precision breeding #RapeseedCRISPR #FunctionalGenomics #OilseedBreeding @academic.oup.com
Details: doi.org/10.1093/hr/u...
Details: doi.org/10.1093/hr/u...
A small-scale CRISPR mutant library in rapeseed of commercial cultivar Zhongshuang 11
Abstract. Rapeseed (Brassica napus L.) is one of the most important oil crops worldwide. In our previous work, we generated a high-throughput CRISPR librar
doi.org
July 16, 2026 at 9:16 AM
A Zhongshuang 11 rapeseed CRISPR mutant library provides a ready resource for functional genomics and precision breeding #RapeseedCRISPR #FunctionalGenomics #OilseedBreeding @academic.oup.com
Details: doi.org/10.1093/hr/u...
Details: doi.org/10.1093/hr/u...
AEpiA 2026 early bird registration and abstract submission have been extended!
Please don’t miss your chance to join us in Adelaide with some amazing speakers lots of fantastic science!
#AEpiA2026 #Epigenetics #Chromatin #GenomeRegulation #FunctionalGenomics #Adelaide
Please don’t miss your chance to join us in Adelaide with some amazing speakers lots of fantastic science!
#AEpiA2026 #Epigenetics #Chromatin #GenomeRegulation #FunctionalGenomics #Adelaide
June 30, 2026 at 9:34 PM
AEpiA 2026 early bird registration and abstract submission have been extended!
Please don’t miss your chance to join us in Adelaide with some amazing speakers lots of fantastic science!
#AEpiA2026 #Epigenetics #Chromatin #GenomeRegulation #FunctionalGenomics #Adelaide
Please don’t miss your chance to join us in Adelaide with some amazing speakers lots of fantastic science!
#AEpiA2026 #Epigenetics #Chromatin #GenomeRegulation #FunctionalGenomics #Adelaide
Only a few hours left for AEpiA 2026 early bird registration and abstract submission!
Join us 14–16 Sept 2026 at the National Wine Centre, Adelaide, for 3 days of epigenetics, chromatin, genome regulation and functional genomics
#AEpiA2026 #Epigenetics #Chromatin #FunctionalGenomics #Adelaide
Join us 14–16 Sept 2026 at the National Wine Centre, Adelaide, for 3 days of epigenetics, chromatin, genome regulation and functional genomics
#AEpiA2026 #Epigenetics #Chromatin #FunctionalGenomics #Adelaide
June 30, 2026 at 1:53 AM
Only a few hours left for AEpiA 2026 early bird registration and abstract submission!
Join us 14–16 Sept 2026 at the National Wine Centre, Adelaide, for 3 days of epigenetics, chromatin, genome regulation and functional genomics
#AEpiA2026 #Epigenetics #Chromatin #FunctionalGenomics #Adelaide
Join us 14–16 Sept 2026 at the National Wine Centre, Adelaide, for 3 days of epigenetics, chromatin, genome regulation and functional genomics
#AEpiA2026 #Epigenetics #Chromatin #FunctionalGenomics #Adelaide
Excellent meeting at #ESHG2026 Gothenburg. The gap between detection and interpretation remains one of the biggest challenges.
The convergence of genetics and cell biology is producing answers that directly impact patients.
🧬 #ESHG2026 #FunctionalGenomics #VariantClassification #RareDiseases
The convergence of genetics and cell biology is producing answers that directly impact patients.
🧬 #ESHG2026 #FunctionalGenomics #VariantClassification #RareDiseases
June 29, 2026 at 5:55 PM
Excellent meeting at #ESHG2026 Gothenburg. The gap between detection and interpretation remains one of the biggest challenges.
The convergence of genetics and cell biology is producing answers that directly impact patients.
🧬 #ESHG2026 #FunctionalGenomics #VariantClassification #RareDiseases
The convergence of genetics and cell biology is producing answers that directly impact patients.
🧬 #ESHG2026 #FunctionalGenomics #VariantClassification #RareDiseases
Explore microbial functionality with #metagenomic analysis. Learn strategies for integrating taxonomic & functional insights to reveal biological mechanisms and advance #microbiome research.
#FunctionalGenomics #Bioinformatics #MicrobialResearch #LifeSciences #Genomics https://tinyurl.com/44c6zvzf
#FunctionalGenomics #Bioinformatics #MicrobialResearch #LifeSciences #Genomics https://tinyurl.com/44c6zvzf
June 28, 2026 at 7:05 AM
Explore microbial functionality with #metagenomic analysis. Learn strategies for integrating taxonomic & functional insights to reveal biological mechanisms and advance #microbiome research.
#FunctionalGenomics #Bioinformatics #MicrobialResearch #LifeSciences #Genomics https://tinyurl.com/44c6zvzf
#FunctionalGenomics #Bioinformatics #MicrobialResearch #LifeSciences #Genomics https://tinyurl.com/44c6zvzf
New Publication:
Mechanistic modeling of recessive disease through allelic integration of variant effects
@uoe-igc.bsky.social
#functionalgenomics #varianteffects #deepmutationalscanning #recessivedisease #enzymebiochemistry
www.sciencedirect.com/science/arti...
Mechanistic modeling of recessive disease through allelic integration of variant effects
@uoe-igc.bsky.social
#functionalgenomics #varianteffects #deepmutationalscanning #recessivedisease #enzymebiochemistry
www.sciencedirect.com/science/arti...
Mechanistic modeling of recessive disease through allelic integration of variant effects
Interpreting variants in recessive diseases is difficult because clinical severity depends on the combined function of both alleles. Deep mutational s…
www.sciencedirect.com
June 26, 2026 at 2:10 PM
New Publication:
Mechanistic modeling of recessive disease through allelic integration of variant effects
@uoe-igc.bsky.social
#functionalgenomics #varianteffects #deepmutationalscanning #recessivedisease #enzymebiochemistry
www.sciencedirect.com/science/arti...
Mechanistic modeling of recessive disease through allelic integration of variant effects
@uoe-igc.bsky.social
#functionalgenomics #varianteffects #deepmutationalscanning #recessivedisease #enzymebiochemistry
www.sciencedirect.com/science/arti...
Explore how Novogene's CRISPR/Cas9 services enabled precise gene knockout & functional validation in a Marburg University study. See methods, outcomes & implications in the full case study. #CRISPR #GeneEditing #FunctionalGenomics https://tinyurl.com/24p8fwmh
June 26, 2026 at 7:05 AM
Explore how Novogene's CRISPR/Cas9 services enabled precise gene knockout & functional validation in a Marburg University study. See methods, outcomes & implications in the full case study. #CRISPR #GeneEditing #FunctionalGenomics https://tinyurl.com/24p8fwmh
Great news for rice researchers!! 🌾
🎉 We've extended the early-bird deadline for ISRFG 2026 (& dropped the price*!!) 🎉
Register before 30th June to save £120!
👉 cvent.me/8VvnrA
@oryzanet.bsky.social #plantscience #rice #functionalgenomics
🎉 We've extended the early-bird deadline for ISRFG 2026 (& dropped the price*!!) 🎉
Register before 30th June to save £120!
👉 cvent.me/8VvnrA
@oryzanet.bsky.social #plantscience #rice #functionalgenomics
June 16, 2026 at 2:35 PM
Great news for rice researchers!! 🌾
🎉 We've extended the early-bird deadline for ISRFG 2026 (& dropped the price*!!) 🎉
Register before 30th June to save £120!
👉 cvent.me/8VvnrA
@oryzanet.bsky.social #plantscience #rice #functionalgenomics
🎉 We've extended the early-bird deadline for ISRFG 2026 (& dropped the price*!!) 🎉
Register before 30th June to save £120!
👉 cvent.me/8VvnrA
@oryzanet.bsky.social #plantscience #rice #functionalgenomics
Generalization matters:
Using PCA-derived tissue representations, it predicts splicing in unseen GTEx tissues and ENCODE cell lines
#FunctionalGenomics #SingleCell #Biotech
Using PCA-derived tissue representations, it predicts splicing in unseen GTEx tissues and ENCODE cell lines
#FunctionalGenomics #SingleCell #Biotech
June 3, 2026 at 5:31 PM
Generalization matters:
Using PCA-derived tissue representations, it predicts splicing in unseen GTEx tissues and ENCODE cell lines
#FunctionalGenomics #SingleCell #Biotech
Using PCA-derived tissue representations, it predicts splicing in unseen GTEx tissues and ENCODE cell lines
#FunctionalGenomics #SingleCell #Biotech
👉 Discover how quantitative proteomics is revealing hidden functions of the gut microbiome and their impact on health and disease.
#Microbiome #QuantitativeProteomics #Proteomics #FunctionalGenomics #Seminar
#Microbiome #QuantitativeProteomics #Proteomics #FunctionalGenomics #Seminar
June 1, 2026 at 12:54 PM
👉 Discover how quantitative proteomics is revealing hidden functions of the gut microbiome and their impact on health and disease.
#Microbiome #QuantitativeProteomics #Proteomics #FunctionalGenomics #Seminar
#Microbiome #QuantitativeProteomics #Proteomics #FunctionalGenomics #Seminar
Full links:
TAP‑seq workflow post: www.linkedin.com/posts/trinob...
Nature paper: www.nature.com/articles/s41...
FIRST‑seq: link.springer.com/article/10.1...
For more content and recaps, give us a follow
TAP‑seq workflow post: www.linkedin.com/posts/trinob...
Nature paper: www.nature.com/articles/s41...
FIRST‑seq: link.springer.com/article/10.1...
For more content and recaps, give us a follow
#trinobia #bioinformatics #singlecellrnaseq #crispr #functionalgenomics #rnaseq #genomics #transcriptomics #biotechnology #computationalbiology #datascience #precisionmedicine #omics #innovation… | Tr...
Sequencing the entire transcriptome for every perturbation is too expensive.
This workflow offers a solution.
TAP-seq (Targeted Perturb-seq) focuses single-cell RNA-seq coverage on a gene panel you d...
www.linkedin.com
May 31, 2026 at 6:21 PM
Full links:
TAP‑seq workflow post: www.linkedin.com/posts/trinob...
Nature paper: www.nature.com/articles/s41...
FIRST‑seq: link.springer.com/article/10.1...
For more content and recaps, give us a follow
TAP‑seq workflow post: www.linkedin.com/posts/trinob...
Nature paper: www.nature.com/articles/s41...
FIRST‑seq: link.springer.com/article/10.1...
For more content and recaps, give us a follow
7/Questions or want to dig into this further?
trinobia.com/contact
#Bioinformatics #SingleCellRNAseq #CRISPR #FunctionalGenomics #Transcriptomics
trinobia.com/contact
#Bioinformatics #SingleCellRNAseq #CRISPR #FunctionalGenomics #Transcriptomics
Contact - Trinobia
Ready to Move Your Data Forward? Let’s Discuss Your Research Project and Start Your Bioinformatics Collaboration Contact Us! Fast, tailored support for your
trinobia.com
May 30, 2026 at 6:10 PM
7/Questions or want to dig into this further?
trinobia.com/contact
#Bioinformatics #SingleCellRNAseq #CRISPR #FunctionalGenomics #Transcriptomics
trinobia.com/contact
#Bioinformatics #SingleCellRNAseq #CRISPR #FunctionalGenomics #Transcriptomics
1/ Sequencing the entire transcriptome for every perturbation is too expensive.
This workflow offers a solution. 🧵
#Trinobia #Bioinformatics #scRNAseq #SingleCell #CRISPR #Genomics #Transcriptomics #RNAseq #FunctionalGenomics #PerturbSeq #TAPseq #NextGenSequencing #NGS #ComputationalBiology
This workflow offers a solution. 🧵
#Trinobia #Bioinformatics #scRNAseq #SingleCell #CRISPR #Genomics #Transcriptomics #RNAseq #FunctionalGenomics #PerturbSeq #TAPseq #NextGenSequencing #NGS #ComputationalBiology
May 30, 2026 at 6:10 PM
1/ Sequencing the entire transcriptome for every perturbation is too expensive.
This workflow offers a solution. 🧵
#Trinobia #Bioinformatics #scRNAseq #SingleCell #CRISPR #Genomics #Transcriptomics #RNAseq #FunctionalGenomics #PerturbSeq #TAPseq #NextGenSequencing #NGS #ComputationalBiology
This workflow offers a solution. 🧵
#Trinobia #Bioinformatics #scRNAseq #SingleCell #CRISPR #Genomics #Transcriptomics #RNAseq #FunctionalGenomics #PerturbSeq #TAPseq #NextGenSequencing #NGS #ComputationalBiology
You can now find the Day 2 presentations from the MSS 2026 over on our YouTube channel. ⏯️ bit.ly/4tzo9hQ
The final day's talks will be live soon, so watch this space!
#VariantEffect26 #Genomics #DeepMutationalScanning #FunctionalGenomics #AtlasOfVariantEffects
The final day's talks will be live soon, so watch this space!
#VariantEffect26 #Genomics #DeepMutationalScanning #FunctionalGenomics #AtlasOfVariantEffects
May 13, 2026 at 7:58 AM
You can now find the Day 2 presentations from the MSS 2026 over on our YouTube channel. ⏯️ bit.ly/4tzo9hQ
The final day's talks will be live soon, so watch this space!
#VariantEffect26 #Genomics #DeepMutationalScanning #FunctionalGenomics #AtlasOfVariantEffects
The final day's talks will be live soon, so watch this space!
#VariantEffect26 #Genomics #DeepMutationalScanning #FunctionalGenomics #AtlasOfVariantEffects
The mechanism is supported by RNA-seq, chromatin assays, and perturbation experiments. Turn IGF1R-AS1 off, enhancer contacts collapse, MYC expression drops. Causality is shown, not assumed.
#RNAseq #ChromatinBiology #CRISPR #FunctionalGenomics #DataDrivenScience
#RNAseq #ChromatinBiology #CRISPR #FunctionalGenomics #DataDrivenScience
May 5, 2026 at 6:51 PM
The mechanism is supported by RNA-seq, chromatin assays, and perturbation experiments. Turn IGF1R-AS1 off, enhancer contacts collapse, MYC expression drops. Causality is shown, not assumed.
#RNAseq #ChromatinBiology #CRISPR #FunctionalGenomics #DataDrivenScience
#RNAseq #ChromatinBiology #CRISPR #FunctionalGenomics #DataDrivenScience