#LongNonCodingRNA
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epigenometech.bsky.social
New Epigenome Technologies Blog! u.epigenome.us/95hqi51J

"XIST Activity in Males: Towards the Evolution of Dosage Compensation"

#Epigenetics #XIST #PairedTag #EpigenomeTech #lncRNAs #LongNonCodingRNA #Chromatin
August 26, 2026 at 7:07 PM
haoyin.bsky.social
#LongNonCodingRNA Liver Fibrosis

LncRNA TILAM
👉Enriched in Activated Hepatic Stellate Cell
👉Located near COL1A1
👉TGFβ-inducible
👉Physically binds to PML➡️maintains PML protein & TGFβ signaling

TILAM LNA or KO⏬Fibrosis in Liver organoid
TILAM KO ⏬🐭Fibrosis

#HEP 2023
journals.lww.com/hep/fulltext...
January 26, 2026 at 8:15 PM
novogene-europe.bsky.social
Discover the significance of long non-coding RNAs with Novogene’s lncRNA sequencing services. Gain insights into gene regulation and disease mechanisms.

Learn more: https://bit.ly/3DpuzLZ

#lncRNA #LongNonCodingRNA #RNASequencing #Transcriptomics #GeneRegulation #GenomicsInnovation
December 19, 2025 at 8:05 AM
stemcellreports.bsky.social
The LINC01612-DVL2-WNT regulatory axis promotes human endoderm differentiation – a key modulator of human definitive endoderm differentiation. #longnoncodingRNA #DVL2 #WNT #endoderm https://ow.ly/zvgJ50XhLB8

ISSCR | Cell Press | The Gairdner Foundation | SickKids Foundation
October 29, 2025 at 1:35 PM
jsantoyo.bsky.social
The emerging roles of long non-coding RNAs in the nervous system. #LongNonCodingRNA #NervousSystem #Genomics @natrevneuro.nature.com 🧬
www.nature.com/articles/s41...
September 6, 2025 at 7:32 AM
novogene-europe.bsky.social
Discover the significance of long non-coding RNAs with Novogene’s lncRNA sequencing services. Gain insights into gene regulation and disease mechanisms.

Learn more: bit.ly/3DpuzLZ

#lncRNA #LongNonCodingRNA #RNASequencing #Transcriptomics #GeneRegulation #GenomicsInnovation
September 5, 2025 at 7:30 AM
pnas.org
#NoncodingRNA drives #evolution and #speciation in the #PepperedMoth, #butterflies, and #MonkeyFlower. Could it also shape #HumanCognition and other #flora and #fauna? A PNAS Inner Workings: www.pnas.org/doi/10.1073/...

#microRNA #LongNoncodingRNA
Peppered Moth. Image credit: Shutterstock/IanRedding.
August 8, 2025 at 6:28 PM
pnas.org
#NoncodingRNA plays a crucial role in #butterfly #speciation and #evolution. But what about other #flora and #fauna—or even the #evolution of human #cognition? A PNAS Inner Workings: www.pnas.org/doi/10.1073/...

#microRNA #LongNoncodingRNA #PepperedMoth #MonkeyFlower
Two pink flowers grow in a patch of grass. Only in recent years have researchers discovered that noncoding RNAs have a significant role in the evolution of the oft-studied plant model system, monkeyflowers. Image credit: Science Source/Stuart Wilson.
August 1, 2025 at 5:15 PM
pnas.org
#NoncodingRNA plays a crucial role in #butterfly #speciation—but what about other #flora and #fauna? A PNAS Inner Workings: www.pnas.org/doi/10.1073/...

#microRNA #LongNoncodingRNA #evolution #PepperedMoth #MonkeyFlower
Four peppered moths on a rock. Recent research suggests that the famous case study of peppered moth evolution has a new twist: their intriguing coloration changes are driven by RNA molecules that don’t code for proteins. How common these cases are is still up for debate. Image credit: Shutterstock/IanRedding.
July 25, 2025 at 5:58 PM
novogene-europe.bsky.social
Discover the significance of long non-coding RNAs with Novogene’s lncRNA sequencing services. Gain insights into gene regulation and disease mechanisms.

Learn more: bit.ly/3DpuzLZ

#lncRNA #LongNonCodingRNA #RNASequencing #Transcriptomics #GeneRegulation #GenomicsInnovation
June 5, 2025 at 7:39 AM
novogene-europe.bsky.social
Discover the significance of long non-coding RNAs with Novogene’s lncRNA sequencing services. Gain insights into gene regulation and disease mechanisms.

Learn more: bit.ly/3DpuzLZ

#lncRNA #LongNonCodingRNA #RNASequencing #Transcriptomics #GeneRegulation #GenomicsInnovation
April 25, 2025 at 7:14 AM
haoyin.bsky.social
#LongNoncodingRNA #SmoothMuscleCell #Seneascence #Atherosclerosis

LncRNA JPX (just proximal to XIST), in complex with #BRD4 NF-κB, transcriptionally activates #SASP in senescent SMCs

SMC Jpx KO⏬🐭#Atherosclerosis +⏬lesional SMC senescence SASP

#ATVB 2024
www.ahajournals.org/doi/10.1161/...
September 8, 2024 at 7:25 PM
haoyin.bsky.social
#LongNonCodingRNA #Senescence #Atherosclerosis

JPX, a chromosome-associated regulatory RNA, complexes with BRD4 & p65 (NFκB subunit) to mediates 3D chromatin remodeling &⏫transcriptional activation of senescence secretome in #SmoothMuscleCell

#ATVB 2024
www.ahajournals.org/doi/10.1161/...
July 24, 2024 at 11:22 AM
haoyin.bsky.social
#LongNonCodingRNA #LncRNA transcriptomics Lower-extremity #PeripheralArteryDisease -/+ T2D #Diabetes

Iliac artery n=79
T2D->⏬ACTA2-AS1

#SmoothMuscleCell microdissected from FFPE section
T2D->⏫LINC00910/RUFY1-AS1 ⏬HIF1A-AS3/XIST!/NEAT1/MIR222HG

#SciReports 2024
www.nature.com/articles/s41...
July 20, 2024 at 7:22 PM
haoyin.bsky.social
#LongNonCodingRNA #SmoothMuscleCell

LncDACH1⏬SMC proliferation+migration & #Neointima of #ArterioVenousFistula, partially via ⏬HSP90 abundance & sequestrating SRPK1 in the nuclei

A similar pro-intimal role in #Atherosclerosis?

#NatureComms 2024
www.nature.com/articles/s41...
May 17, 2024 at 7:50 PM
haoyin.bsky.social
Enhancer-associated #LongNonCodingRNA #Atherosclerosis

PSMB8-AS1⏫promixal gene transcription of PSMB9 in #EndothelialCell->
Zeb1->
VCAM1/ICAM1->
#VascularInflammation #Atherosclerosis

Serum lipids also regulated by PSMB8-AS1

#CircRes 2023
www.ahajournals.org/doi/10.1161/...
December 19, 2023 at 7:31 PM