Muscles growth by sarcomere divisions - how your muscles add new sarcomeres during developmental growth: they divide! Cool collaboration @friedrich-group.bsky.social @raunser-lab.bsky.social @Dirk Görlich @univ-amu.fr @cnrs.bsky.social sciencecast.org/casts/aspy9l... www.biorxiv.org/content/10.1...
December 19, 2024 at 11:08 AM
What a treat to be interviewed on NPR about our lab’s newest paper! We share our findings on how bottom-up signaling from muscles during exercise helps motor neurons grow 💪🏽 #myoblue
Links to interview + paper:
www.npr.org/2024/11/14/n...
onlinelibrary.wiley.com/doi/10.1002/...
Links to interview + paper:
www.npr.org/2024/11/14/n...
onlinelibrary.wiley.com/doi/10.1002/...
November 20, 2024 at 1:50 PM
What a treat to be interviewed on NPR about our lab’s newest paper! We share our findings on how bottom-up signaling from muscles during exercise helps motor neurons grow 💪🏽 #myoblue
Links to interview + paper:
www.npr.org/2024/11/14/n...
onlinelibrary.wiley.com/doi/10.1002/...
Links to interview + paper:
www.npr.org/2024/11/14/n...
onlinelibrary.wiley.com/doi/10.1002/...
10 years post-PhD and finally…the promotion and tenure pour. Shout out to all my mentors, collaborators, colleagues, and trainees. Science is a team sport, and my team is all MVPs. #myoblue
March 18, 2025 at 12:56 AM
10 years post-PhD and finally…the promotion and tenure pour. Shout out to all my mentors, collaborators, colleagues, and trainees. Science is a team sport, and my team is all MVPs. #myoblue
Excited to share this new collaborative #EmboMolMed work from my lab #ChildrensAL & Jim Dowling labs. Work highlights efforts to generate a new animal model for X-linked myopathy with excessive autophagy (XMEA) and perform corrective drug screening. 1/n tinyurl.com/ym7svnwm
X-linked myopathy with excessive autophagy: characterization and therapy testing in a zebrafish model | EMBO Molecular Medicine
imageimageX-linked myopathy with excessive autophagy (XMEA) is a rare disease for which pre-clinical
models lack, challenging the ability to understand mechanisms and therapies. The use
of the zebrafi...
tinyurl.com
February 25, 2025 at 2:04 AM
New review on FAPs by @jyotijaiswal.bsky.social and colleagues
Exploring the therapeutic potential of fibroadipogenic progenitors in muscle disease
journals.sagepub.com/doi/full/10....
Exploring the therapeutic potential of fibroadipogenic progenitors in muscle disease
journals.sagepub.com/doi/full/10....
February 18, 2025 at 1:24 PM
Polyamine metabolism dysregulation contributes to muscle fiber vulnerability in ALS
www.cell.com/cell-reports...
www.cell.com/cell-reports...
Polyamine metabolism dysregulation contributes to muscle fiber vulnerability in ALS
Ruggieri et al. developed a spatial transcriptomics dataset of skeletal muscle from
the SOD1G93A ALS mouse model. Their findings highlight polyamine metabolism’s role
in muscle fiber vulnerability, sh...
www.cell.com
February 12, 2025 at 1:09 AM
I’m honoured to receive a CIHR-IMHA Inclusive Research Excellence Prize for our use of Open Science. Check out our open resources:
www.addgene.org/search/catal...
www.jax.org/strain/039220
www.biorxiv.org/search/autho...
MF593120, MF156210
#myoblue @addgene.bsky.social
www.addgene.org/search/catal...
www.jax.org/strain/039220
www.biorxiv.org/search/autho...
MF593120, MF156210
#myoblue @addgene.bsky.social
Addgene
www.addgene.org
July 15, 2025 at 7:07 PM
I’m honoured to receive a CIHR-IMHA Inclusive Research Excellence Prize for our use of Open Science. Check out our open resources:
www.addgene.org/search/catal...
www.jax.org/strain/039220
www.biorxiv.org/search/autho...
MF593120, MF156210
#myoblue @addgene.bsky.social
www.addgene.org/search/catal...
www.jax.org/strain/039220
www.biorxiv.org/search/autho...
MF593120, MF156210
#myoblue @addgene.bsky.social
Tag us @myoblue.bsky.social or use #MyoBlue to alert us to new papers, job postings, conference/seminar announcements, or professional accomplishments! This account was created to share any and everything #MyoBlue -related. Please RT to help better connect our community!
November 18, 2024 at 8:10 PM
Tag us @myoblue.bsky.social or use #MyoBlue to alert us to new papers, job postings, conference/seminar announcements, or professional accomplishments! This account was created to share any and everything #MyoBlue -related. Please RT to help better connect our community!
Let’s try out this new platform by sharing our recent paper on the transcriptional signatures of individual muscle fibers following high-intensity exercise
#myoblue #myosky
journals.physiology.org/doi/abs/10.1...
#myoblue #myosky
journals.physiology.org/doi/abs/10.1...
November 18, 2024 at 7:56 PM
Let’s try out this new platform by sharing our recent paper on the transcriptional signatures of individual muscle fibers following high-intensity exercise
#myoblue #myosky
journals.physiology.org/doi/abs/10.1...
#myoblue #myosky
journals.physiology.org/doi/abs/10.1...
Congratulations team! 👍
This will be of interest for muscle physiologists #MyoBlue @myoblue.bsky.social
This will be of interest for muscle physiologists #MyoBlue @myoblue.bsky.social
A human specific lncRNA important for ribosomal biogenesis in skeletal muscle- reduced in people with type 2 diabetes.Latest from the team! @ilkesen.bsky.social @juleenrzierath.bsky.social Science Advances www.science.org/doi/10.1126/...
Down-regulation of human-specific lncRNA TMEM9B-AS1 in skeletal muscle of people with type 2 diabetes affects ribosomal biogenesis
TMEM9B-AS1, down-regulated in type 2 diabetes, regulates ribosomal biogenesis in muscle by promoting IGF2BP1-MYC mRNA interaction.
www.science.org
July 9, 2025 at 9:31 PM
Congratulations team! 👍
This will be of interest for muscle physiologists #MyoBlue @myoblue.bsky.social
This will be of interest for muscle physiologists #MyoBlue @myoblue.bsky.social
November 21, 2024 at 9:20 PM
Our latest! Great work from Ben Stocks and Atul Deshmukh!
Temporal dynamics of the interstitial fluid proteome in human skeletal muscle following exhaustive exercise | Science Advances www.science.org/doi/10.1126/...
Temporal dynamics of the interstitial fluid proteome in human skeletal muscle following exhaustive exercise | Science Advances www.science.org/doi/10.1126/...
Temporal dynamics of the interstitial fluid proteome in human skeletal muscle following exhaustive exercise
Exercise regulates the human skeletal muscle interstitial fluid proteome in a distinct temporal manner.
www.science.org
February 2, 2025 at 1:47 PM
March 17, 2025 at 1:02 PM
please exercise, and encourage your loved ones to do the same. Happy Valentine's day ❤️
Skeletal muscle growth to combat diabetes and obesity: the potential role of muscle‐secreted factors
As the prevalence of obesity and metabolic disease continues to climb, the need for effective therapeutic interventions remains high. The growth of skeletal muscle (SkM) greatly influences systemic m...
onlinelibrary.wiley.com
February 14, 2025 at 7:16 PM
A really nice special issue in @jphysiol.bsky.social by Dr. Chris Sundberg “Physiology of ageing skeletal muscle and the protective effects of exercise” feat. some work by our lab and many others! Check it out @myoblue.bsky.social physoc.onlinelibrary.wiley.com/toc/14697793...
Special Issue: Physiology of ageing skeletal muscle and the protective effects of exercise: The Journal of Physiology: Vol 603, No 1
<em>The Journal of Physiology</em> publishes research in all areas of physiology and pathophysiology that illustrates new physiological principles or mechanisms.
physoc.onlinelibrary.wiley.com
January 6, 2025 at 7:47 PM
Congrats to #JF_CoteLab and colleagues for their new #DevelopmentJ paper: Differentially expressed fusogens specify myocyte states to drive myogenesis. #Myoblue tinyurl.com/ykbbex8t
tinyurl.com
September 17, 2025 at 11:47 AM
Congrats to #JF_CoteLab and colleagues for their new #DevelopmentJ paper: Differentially expressed fusogens specify myocyte states to drive myogenesis. #Myoblue tinyurl.com/ykbbex8t
Our call for papers has been extended until July 1st. We look forward to receiving your manuscript. #myoblue
journals.physiology.org/jappl/contex...
journals.physiology.org/jappl/contex...
February 15, 2025 at 1:01 AM
Our call for papers has been extended until July 1st. We look forward to receiving your manuscript. #myoblue
journals.physiology.org/jappl/contex...
journals.physiology.org/jappl/contex...
Delighted to share a new preprint from the lab:
Fat1 deletion enhances Fibro-Adipogenic Differentiation and Adipogenic expansion following injury in skeletal muscle
doi.org/10.64898/202...
#Myoblue #FAPs #IMAT #muscleregeneration #adipogenesis #skeletalmuscle
Fat1 deletion enhances Fibro-Adipogenic Differentiation and Adipogenic expansion following injury in skeletal muscle
doi.org/10.64898/202...
#Myoblue #FAPs #IMAT #muscleregeneration #adipogenesis #skeletalmuscle
April 25, 2026 at 11:07 AM
Delighted to share a new preprint from the lab:
Fat1 deletion enhances Fibro-Adipogenic Differentiation and Adipogenic expansion following injury in skeletal muscle
doi.org/10.64898/202...
#Myoblue #FAPs #IMAT #muscleregeneration #adipogenesis #skeletalmuscle
Fat1 deletion enhances Fibro-Adipogenic Differentiation and Adipogenic expansion following injury in skeletal muscle
doi.org/10.64898/202...
#Myoblue #FAPs #IMAT #muscleregeneration #adipogenesis #skeletalmuscle