Since last year, I've been making a RELION GUI that supports viewing, navigating and running jobs in a way completely compatible with the original RELION pipeline. Now it's working nicely for both SPA and tomography! Please try it out - github.com/hanjinliu/hi...
February 22, 2026 at 8:10 PM
Since last year, I've been making a RELION GUI that supports viewing, navigating and running jobs in a way completely compatible with the original RELION pipeline. Now it's working nicely for both SPA and tomography! Please try it out - github.com/hanjinliu/hi...
Initial attempt at replicating in relion (parameters in next post). This is for Aca2-RNA, using a 100k subset of the 2D-classified particles (no prior 3D cleanup).
A 1-class ab initio in relion, then local refinement in relion (1.8deg searches+blush) gives a nominally 3.3Å map; 3.5 Å w/out blush.
A 1-class ab initio in relion, then local refinement in relion (1.8deg searches+blush) gives a nominally 3.3Å map; 3.5 Å w/out blush.
September 26, 2025 at 2:28 AM
Initial attempt at replicating in relion (parameters in next post). This is for Aca2-RNA, using a 100k subset of the 2D-classified particles (no prior 3D cleanup).
A 1-class ab initio in relion, then local refinement in relion (1.8deg searches+blush) gives a nominally 3.3Å map; 3.5 Å w/out blush.
A 1-class ab initio in relion, then local refinement in relion (1.8deg searches+blush) gives a nominally 3.3Å map; 3.5 Å w/out blush.
Oh wow, this is 🤯 amazing: ~3-fold acceleration of running #relion on A100 GPUs for realistic single-particle refinement by the group of Guangwen Yang at @tsinghuauniversity.bsky.social
.
What a fantastic example of #OpenSoftwareAcceleratesScience, literally! 😍
dl.acm.org/doi/full/10....
.
What a fantastic example of #OpenSoftwareAcceleratesScience, literally! 😍
dl.acm.org/doi/full/10....
T2-RELION: Task Parallelism, Tensor Core Accelerated RELION for Cryo-EM 3D Reconstruction | Proceedings of the International Conference for High Performance Computing, Networking, Storage and Analysis
dl.acm.org
November 21, 2025 at 12:32 PM
Oh wow, this is 🤯 amazing: ~3-fold acceleration of running #relion on A100 GPUs for realistic single-particle refinement by the group of Guangwen Yang at @tsinghuauniversity.bsky.social
.
What a fantastic example of #OpenSoftwareAcceleratesScience, literally! 😍
dl.acm.org/doi/full/10....
.
What a fantastic example of #OpenSoftwareAcceleratesScience, literally! 😍
dl.acm.org/doi/full/10....
We're excited to announce the beta-release of #RELION-5.1! 🥳 This release has important updates on our #amyloid processing pipeline, as described in this preprint: doi.org/10.64898/202... There are also some tweaks for #teamtomo.
#OpenSoftwareAcceleratesScience
#OpenSoftwareAcceleratesScience
March 18, 2026 at 11:52 AM
We're excited to announce the beta-release of #RELION-5.1! 🥳 This release has important updates on our #amyloid processing pipeline, as described in this preprint: doi.org/10.64898/202... There are also some tweaks for #teamtomo.
#OpenSoftwareAcceleratesScience
#OpenSoftwareAcceleratesScience
If it helps anyone receiving a rejection today: my original paper on #RELION was rejected by @pnas.org and Structure @cellpressnews.bsky.social. The method still did pretty well.
Sometimes you just have to persevere through negative reviews. Reviewers, please be kind :) #methodsmatter bit.ly/gs2-scholar
November 25, 2024 at 8:57 AM
If it helps anyone receiving a rejection today: my original paper on #RELION was rejected by @pnas.org and Structure @cellpressnews.bsky.social. The method still did pretty well.
1/5: Over the last few months, I have been working on an update for the #FollowRelionGracefully dashboard, which offers improved real-time job previews for #cryoEM #Relion jobs.
April 27, 2025 at 8:49 PM
1/5: Over the last few months, I have been working on an update for the #FollowRelionGracefully dashboard, which offers improved real-time job previews for #cryoEM #Relion jobs.
At some point, Doppio will replace relion's gui. Already you can do more in Doppio than in relion! 🤩
We are pleased to announce Doppio version 1.4! Available here www.ccpem.ac.uk/software/dow...
Downloads – CCP-EM
www.ccpem.ac.uk
November 4, 2025 at 6:14 PM
At some point, Doppio will replace relion's gui. Already you can do more in Doppio than in relion! 🤩
You can download RELION-5.1 from github.com/3dem/relion (branch ver5.1)
Note that the beautiful startup image of dynein:dynactin on a microtubule was provided by Sami Chabaan from the @carter-lab.bsky.social. 🤗
Note that the beautiful startup image of dynein:dynactin on a microtubule was provided by Sami Chabaan from the @carter-lab.bsky.social. 🤗
GitHub - 3dem/relion: Image-processing software for cryo-electron microscopy
Image-processing software for cryo-electron microscopy - 3dem/relion
github.com
March 18, 2026 at 11:55 AM
You can download RELION-5.1 from github.com/3dem/relion (branch ver5.1)
Note that the beautiful startup image of dynein:dynactin on a microtubule was provided by Sami Chabaan from the @carter-lab.bsky.social. 🤗
Note that the beautiful startup image of dynein:dynactin on a microtubule was provided by Sami Chabaan from the @carter-lab.bsky.social. 🤗
Always excited when Relion changes its color 😍.
We're excited to announce the beta-release of #RELION-5.1! 🥳 This release has important updates on our #amyloid processing pipeline, as described in this preprint: doi.org/10.64898/202... There are also some tweaks for #teamtomo.
#OpenSoftwareAcceleratesScience
#OpenSoftwareAcceleratesScience
March 18, 2026 at 8:17 PM
Always excited when Relion changes its color 😍.
The reason why this site is dying isnt metrics or pile on culture, its because of people like me, in their 40s, making references to pre-Atlantic records era Bad Relion
August 12, 2026 at 9:00 PM
The reason why this site is dying isnt metrics or pile on culture, its because of people like me, in their 40s, making references to pre-Atlantic records era Bad Relion
You may wonder which keyboard I use, anyone else have this one?
November 17, 2025 at 3:43 PM
You may wonder which keyboard I use, anyone else have this one?
Job navigation in table view, searchable tags, 3D mesh optimized for masks, and many more features! 👉👉👉
github.com/hanjinliu/hi...
Let's make our RELION directory a better place.
github.com/hanjinliu/hi...
Let's make our RELION directory a better place.
May 9, 2026 at 6:26 PM
Job navigation in table view, searchable tags, 3D mesh optimized for masks, and many more features! 👉👉👉
github.com/hanjinliu/hi...
Let's make our RELION directory a better place.
github.com/hanjinliu/hi...
Let's make our RELION directory a better place.
happy #portfolioday!
i'm rhi/relion, i love drawing fanart of my fav characters and dark fantasy
ko-fi: ko-fi.com/relion
📩: @reli0n on discord | reli0n@protonmail.com
🎨: cara.app/relion
i'm rhi/relion, i love drawing fanart of my fav characters and dark fantasy
ko-fi: ko-fi.com/relion
📩: @reli0n on discord | reli0n@protonmail.com
🎨: cara.app/relion
January 13, 2026 at 8:45 PM
happy #portfolioday!
i'm rhi/relion, i love drawing fanart of my fav characters and dark fantasy
ko-fi: ko-fi.com/relion
📩: @reli0n on discord | reli0n@protonmail.com
🎨: cara.app/relion
i'm rhi/relion, i love drawing fanart of my fav characters and dark fantasy
ko-fi: ko-fi.com/relion
📩: @reli0n on discord | reli0n@protonmail.com
🎨: cara.app/relion
We are looking for a computational postdoc to work with us on new optimisation algorithms to make #RELION even better. Join our bubbly team at the @mrclmb.bsky.social in Cambridge, UK. 🤗 RTs appreciated.
mrc.tal.net/vx/appcentre...
mrc.tal.net/vx/appcentre...
Quick Check Needed
mrc.tal.net
October 29, 2025 at 9:17 AM
We are looking for a computational postdoc to work with us on new optimisation algorithms to make #RELION even better. Join our bubbly team at the @mrclmb.bsky.social in Cambridge, UK. 🤗 RTs appreciated.
mrc.tal.net/vx/appcentre...
mrc.tal.net/vx/appcentre...
We're pleased to announce that #RELION5 is now available for beta testing! 🥳🥳🥳 Download it for free from github.com/3dem/relion/...
#OpenSoftwareAcceleratesScience
#OpenSoftwareAcceleratesScience
October 26, 2023 at 4:22 PM
We're pleased to announce that #RELION5 is now available for beta testing! 🥳🥳🥳 Download it for free from github.com/3dem/relion/...
#OpenSoftwareAcceleratesScience
#OpenSoftwareAcceleratesScience
Excellent #postdoc opportunity available in @sjorsscheres.bsky.social’ group, working on new image processing algorithms for #cryoEM structure determination in their #RELION open-source software.
www.nature.com/naturecareer...
Apply by 25 NOV
#PostdocJobs #ScienceJobs
www.nature.com/naturecareer...
Apply by 25 NOV
#PostdocJobs #ScienceJobs
November 6, 2025 at 3:46 PM
Excellent #postdoc opportunity available in @sjorsscheres.bsky.social’ group, working on new image processing algorithms for #cryoEM structure determination in their #RELION open-source software.
www.nature.com/naturecareer...
Apply by 25 NOV
#PostdocJobs #ScienceJobs
www.nature.com/naturecareer...
Apply by 25 NOV
#PostdocJobs #ScienceJobs
It's a small project, but hopefully useful for others running RELION jobs.
GitHub: github.com/bfcoop/relio...
Feedback and feature suggestions are very welcome!
#CryoEM #RELION #StructuralBiology #OpenSource
GitHub: github.com/bfcoop/relio...
Feedback and feature suggestions are very welcome!
#CryoEM #RELION #StructuralBiology #OpenSource
GitHub - bfcoop/relion_tracker: Track metrics from RELION optimiser STAR files directly in the terminal.
Track metrics from RELION optimiser STAR files directly in the terminal. - bfcoop/relion_tracker
github.com
June 2, 2026 at 8:11 PM
It's a small project, but hopefully useful for others running RELION jobs.
GitHub: github.com/bfcoop/relio...
Feedback and feature suggestions are very welcome!
#CryoEM #RELION #StructuralBiology #OpenSource
GitHub: github.com/bfcoop/relio...
Feedback and feature suggestions are very welcome!
#CryoEM #RELION #StructuralBiology #OpenSource
Just for fun, reprocessed a subset (1200 mics) of EMPIAR-11918 (beautiful 40kDa RNA-protein complex) with cryoSPARC to compare with BLUSH/RELION workflow - 3Å NU-refine from 60k blob-picked particles after quick classification without alignments
December 6, 2024 at 3:25 AM
Just for fun, reprocessed a subset (1200 mics) of EMPIAR-11918 (beautiful 40kDa RNA-protein complex) with cryoSPARC to compare with BLUSH/RELION workflow - 3Å NU-refine from 60k blob-picked particles after quick classification without alignments
#TeamTomo if you want to use CTF-corrected 3D subtomos from AreTomo3 in RELION v.5.1 you can use this updated script:
github.com/Phaips/aretomo3torelion5
github.com/Phaips/aretomo3torelion5
GitHub - Phaips/aretomo3torelion5
Contribute to Phaips/aretomo3torelion5 development by creating an account on GitHub.
github.com
March 20, 2026 at 2:54 PM
#TeamTomo if you want to use CTF-corrected 3D subtomos from AreTomo3 in RELION v.5.1 you can use this updated script:
github.com/Phaips/aretomo3torelion5
github.com/Phaips/aretomo3torelion5
hi #portfolioday!
i'm rhi, a freelance illustrator from the uk. i'm ride or die for the worst characters 😈
ko-fi: ko-fi.com/relion
📩: rhi.tristram@gmail.com
🎨: cara.app/relion
i'm rhi, a freelance illustrator from the uk. i'm ride or die for the worst characters 😈
ko-fi: ko-fi.com/relion
📩: rhi.tristram@gmail.com
🎨: cara.app/relion
April 8, 2025 at 4:38 PM
hi #portfolioday!
i'm rhi, a freelance illustrator from the uk. i'm ride or die for the worst characters 😈
ko-fi: ko-fi.com/relion
📩: rhi.tristram@gmail.com
🎨: cara.app/relion
i'm rhi, a freelance illustrator from the uk. i'm ride or die for the worst characters 😈
ko-fi: ko-fi.com/relion
📩: rhi.tristram@gmail.com
🎨: cara.app/relion
Using github.com/hanjinliu/hi... installed in native Windows to run RELION installed in WSL -- as if you are running RELION in Windows!
September 28, 2026 at 9:10 AM
Using github.com/hanjinliu/hi... installed in native Windows to run RELION installed in WSL -- as if you are running RELION in Windows!
Just installed and twiddled a few knobs, but I am already impressed with `himena relion`. Amazing job @liu-hanjin.bsky.social! Would be great if this could be made into a default interface for relion.
February 24, 2026 at 8:29 PM
Just installed and twiddled a few knobs, but I am already impressed with `himena relion`. Amazing job @liu-hanjin.bsky.social! Would be great if this could be made into a default interface for relion.
I've just released a small open-source utility for RELION users: relion_tracker.
RELION stores a lot of useful information in the *_optimiser.star files, but I often found myself repeatedly grepping STAR files to see how metrics were changing across iterations.
RELION stores a lot of useful information in the *_optimiser.star files, but I often found myself repeatedly grepping STAR files to see how metrics were changing across iterations.
June 2, 2026 at 8:11 PM
I've just released a small open-source utility for RELION users: relion_tracker.
RELION stores a lot of useful information in the *_optimiser.star files, but I often found myself repeatedly grepping STAR files to see how metrics were changing across iterations.
RELION stores a lot of useful information in the *_optimiser.star files, but I often found myself repeatedly grepping STAR files to see how metrics were changing across iterations.
www.biorxiv.org/content/10.1... Example of Relion Blush regularisation combined with CryoDRGN to overcome orientation bias issues from Teder et al #CryoEM
November 30, 2025 at 4:23 PM
www.biorxiv.org/content/10.1... Example of Relion Blush regularisation combined with CryoDRGN to overcome orientation bias issues from Teder et al #CryoEM