Phage therapy is providing a benefit to a limited number of people. To date those who have received phage therapy typically have done so via an IND expanded access mechanism, colloquially referred to ...

Leishmania species are transmitted between mammals by sand flies, within which they undergo a complex developmental programme involving transitions between replicative and non-replicative life cycle f...

Dotplot is a nice way to visualize scRNAseq expression data across clusters. It gives information (by color) for the average expression level across cells within the cluster and the percentage (by size of the dot) of the cells express that gene within the cluster. Seurat has a nice function for that. However, it can not do the clustering for the rows and columns. David McGaughey has written a blog post using ggplot2 and ggtree from Guangchuang Yu.

Hands on training in long‑read single‑cell RNA‑seq, from experimental design to data interpretation

Hands on training in long‑read single‑cell RNA‑seq, from experimental design to data interpretation

why this blog post? I saw a biorxiv paper titled A comparison of marker gene selection methods for single-cell RNA sequencing data Our results highlight the efficacy of simple methods, especially the Wilcoxon rank-sum test, Student’s t-test and logistic regression I am interested in using logistic regression to find marker genes and want to try fitting the model in the tidymodel ecosystem and using different regularization methods.

Abstract. Infantile hemangioma (IH), a benign vascular tumor of infancy, is characterized by rapid postnatal growth and subsequent spontaneous resolution.