#SystemsBiology
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royalsocietypublishing.org
New research from #JRSocInterface: Elucidating the effect of spatial localization on metabolic systems doi.org/10.1098/rsif... | #Biomathematics #SyntheticBiology #SystemsBiology
October 30, 2026 at 3:02 PM
rituparnagoswami.bsky.social
Our new Prepring is out! We show transcriptional variability in heat stress response and how plants control it. #plantbiology #systemsbiology #heatstress #heterogeneity #transcriptonalNoise #singlecell
biorxiv-plants.bsky.social bioRxiv Plant Bio @biorxiv-plants.bsky.social · 8d
Regulatory architecture tunes gene expression noise in the plant heat shock response https://www.biorxiv.org/content/10.64898/2026.10.22.760979v1
October 25, 2026 at 4:27 PM
jaceblog.bsky.social
Population Dynamics & Resource Constraints

Why does a successful first generation fail to produce a lasting lineage?

Replication goes beyond body shape. Cell density, boundaries, and resources all matter.

The environment is part of design.

#SystemsBiology #Xenobots #Robotics #EvolutionaryDesign
October 25, 2026 at 10:26 PM
barcelonacollaboratorium.com
A big thank you to Rubén Pérez-Carrasco from Imperial College London for his fascinating seminar at the Collaboratorium today!

Thank you for sharing your exciting research and insights with us!

#Collaboratorium #SystemsBiology #Seminar #Research
October 22, 2026 at 10:12 AM
moebr.bsky.social
Our new @CellStemCell paper explores the missing half: "Subtractive Tissue Engineering" is what we named it. 🧵#development #celldeath #syntheticbiology #systemsbiology #embryogenesis #organoids #NAMs #human #stemcell
October 22, 2026 at 9:24 PM
royalsocietypublishing.org
New research from #BiologyLetters: Ploidy is associated with multielemental reorganization across soft and mineralized body compartments doi.org/10.1098/rsbl... | #Ecology #SystemsBiology
October 20, 2026 at 3:03 PM
tenuretracker.bsky.social
University of California, Berkeley (UCB) (@ucberkeleyofficial.bsky.social) is hiring:
Postdoc Scholar Employee in Systems Biology – Molecular & Cell Biology

#postdoc #biology #systemsbiology
October 17, 2026 at 3:38 AM
jcb.org
Single-cell imaging reveals a key role of Bck2 in #yeast cell size adaptation to nutrient challenges. New study from Yagya Chadha, Kurt M. Schmoller and colleagues @helmholtzmunich.bsky.social:
rupress.org/jcb/article/...

#SystemsBiology #ComputationalBiology #CellCycle #CellDivision #Microbiology
October 16, 2026 at 1:45 PM
labmonteiro.bsky.social
PhD project available through @MIBTP (BBSRC-funded)
investigating how blood flow instructs the embryo to make blood stem cells.
A wet lab+computational project for anyone interested in stem cells, development and systems biology.

Please share!
#PhD #StemCells #Zebrafish #SystemsBiology #BBSRC
Application
Application
warwick.ac.uk
October 15, 2026 at 8:26 PM
signalfield.bsky.social
Life was electrical before thought.

Cells hold voltage across membranes.
Tissues coordinate.
Networks emerge.

The beautiful systems question is what becomes possible when many local signals begin acting together.

#SignalScienceLab #Bioelectricity #SystemsBiology
October 14, 2026 at 8:05 PM
evgenii-protasov.bsky.social
Higher-order assembly and emergent persistence in biology
#biology #SystemsBiology #MicroSky
www.sciencedirect.com/science/arti...
Higher-order assembly and emergent persistence in biology
Biological systems often maintain functional organization for far longer than the molecular, cellular, or ecological interactions from which it emerge…
www.sciencedirect.com
October 13, 2026 at 6:17 AM
Biologists: what makes many parts one living system?
This theoretical framework examines boundaries and relations. Which assumption would you test?
Yao Wu — Independent Researcher
doi.org/10.5281/zeno...
#Biology #SystemsBiology
October 13, 2026 at 12:01 PM
Biologists: what makes many parts one living system?
This theoretical framework examines boundaries and relations. Which assumption would you test?
Yao Wu — Independent Researcher
doi.org/10.5281/zeno...
#Biology #SystemsBiology
October 12, 2026 at 12:01 PM
csbj.org
🔗 A Boolean Seven-Layer Platelet Decision Model Models Consistently the Logic and Semiquantitatively the Dynamics of Platelet Activation and Inhibition. doi.org/10.34133/csb...

📚 CSBJ - A Science Partner Journal: spj.science.org/journal/csbj

@embl.org @csbj.org #SystemsBiology #Thrombosis
A Boolean Seven-Layer Platelet Decision Model Models Consistently the Logic and Semiquantitatively the Dynamics of Platelet Activation and Inhibition. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0228 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj
October 12, 2026 at 4:54 AM
Biologists: what makes many parts one living system?
This theoretical framework examines boundaries and relations. Which assumption would you test?
Yao Wu — Independent Researcher
doi.org/10.5281/zeno...
#Biology #SystemsBiology
October 11, 2026 at 12:00 PM
Biologists: what makes many parts one living system?
This theoretical framework examines boundaries and relations. Which assumption would you test?
Yao Wu — Independent Researcher
doi.org/10.5281/zeno...
#Biology #SystemsBiology
October 10, 2026 at 12:01 PM
Biologists: what makes many parts one living system?
This theoretical framework examines boundaries and relations. Which assumption would you test?
Yao Wu — Independent Researcher
doi.org/10.5281/zeno...
#Biology #SystemsBiology
October 9, 2026 at 12:01 PM
Biologists: what makes many parts one living system?
This theoretical framework examines boundaries and relations. Which assumption would you test?
Yao Wu — Independent Researcher
doi.org/10.5281/zeno...
#Biology #SystemsBiology
October 8, 2026 at 12:01 PM
Biologists: what makes many parts one living system?
This theoretical framework examines boundaries and relations. Which assumption would you test?
Yao Wu — Independent Researcher
doi.org/10.5281/zeno...
#Biology #SystemsBiology
October 6, 2026 at 12:01 PM
royalsocietypublishing.org
New #JRSocInterface research uses computer modelling to reveal how rhythmic pumping and valves in cervical lymphatic vessels work together to drain waste from the brain, offering insights that could help inform future treatments doi.org/10.1098/rsif... | #Bioengineering #Biomechanics #SystemsBiology
October 5, 2026 at 11:01 AM
csbj.org
🔗 Graph Topology Reframes the Coherence of Cell-State Manifold Inference under Heterogeneous Single-Cell Observations. doi.org/10.34133/csb...

📚 CSBJ - A Science Partner Journal: spj.science.org/journal/csbj

@csbj.org #scRNAseq #SingleCellOmics #Transcriptomics #SystemsBiology #CellBiology #Omics
Graph Topology Reframes the Coherence of Cell-State Manifold Inference under Heterogeneous Single-Cell Observations. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0087 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj
September 28, 2026 at 8:40 PM
fds3rd.bsky.social
Bacteria against Mutants
#StemCells #SystemsBiology #Viruses #Microorganisms #Evolution #Development
Bacteria against Mutants - Weizmann Wonder Wander - News, Features and Discoveries
A bacterial model helps reveal how our bodies prevent population explosions – and cancer
wis-wander.weizmann.ac.il
September 26, 2026 at 6:01 PM
fds.wsocial.eu
Bacteria against Mutants
#StemCells #SystemsBiology #Viruses #Microorganisms #Evolution #Development
Bacteria against Mutants - Weizmann Wonder Wander - News, Features and Discoveries
A bacterial model helps reveal how our bodies prevent population explosions – and cancer
wis-wander.weizmann.ac.il
September 26, 2026 at 6:01 PM
royalsocietypublishing.org
New research from #JRSocInterface: Cycling cadence selections at different saddle heights minimize muscle activation rather than energy cost doi.org/10.1098/rsif... | #Biomechanics #Biophysics #SystemsBiology
September 19, 2026 at 9:00 AM
alicefrolov.bsky.social
Cell-fate partitioning after senescence induction: modeling SASP-driven escape trajectories

#CellularSenescence #SASP #CellCycleReentry #SenescenceEscape #TumorSuppression #NFkBSignaling #SystemsBiology #ComputationalCellBiology
Cell-fate partitioning after senescence induction: modeling SASP-driven escape trajectories I am sharing a data visualization that formalizes an increasingly discussed but underappreciated phenomenon in the senescence literature: the capacity of a subpopulation of arrested cells to re-enter the cell cycle rather than remaining stably arrested or undergoing clearance. The figure, titled "Cell-fate partitioning after senescence induction," uses a bidirectional flow trajectory (streamgraph-style stacked area) to render the temporal redistribution of an initial senescent-induced cohort across three terminal or quasi-terminal states over a 30-day window: stable arrest, apoptotic clearance, and senescence escape. The subtitle emphasizes that these are simulated dynamics, not empirical measurements; the parameterization is literature-grounded, calibrated to reported ranges for p16INK4a/p21CIP1 durability, SASP factor accumulation kinetics, and escape frequencies observed in oncogene- and therapy-induced senescence models. The streamgraph format is deliberate. Because escape is a flux phenomenon rather than a static endpoint, the bidirectional banding captures net transitions between compartments, including the small but non-negligible reflux from a metastable arrested state back into proliferation. The simulation encodes a positive-feedback term whereby paracrine and autocrine SASP components — principally IL-6, IL-8, and other NF-κB-dependent secreted factors — lower the effective barrier to CDK reactivation in cells with attenuated tumor-suppressor signaling. The escape band consequently widens after the SASP matures, roughly days 8 to 15 in this parameterization, consistent with the delayed secretory phenotype. I would welcome critique on the transition-rate assumptions, particularly the coupling coefficient between SASP intensity and escape probability, which remains poorly constrained empirically.
September 18, 2026 at 5:01 PM