#SynapticPlasticity
Can IGF-1 Therapy Drive a 44.3% Increase in Verbal Complexity in Severe Autism? 🧠⚡

Source: Kolevzon et al., Molecular Autism
​#increlex #synapticplasticity #synaptogenesis #neuroregeneration #autismspectrumdisorder #apraxiaofspeech #verbalcommunication #pediatricneuroscience #neurotrophicfactors
November 3, 2026 at 3:24 PM
October 26, 2026 at 2:07 AM
🧠 Just published online in JPS❣️
“Toll-like receptor signaling modulates AMPA receptor trafficking in homeostatic synaptic downscaling”
— Akira Koga et al.
🔗 doi.org/10.1016/j.jp...
#Neuroscience #SynapticPlasticity #AMPAReceptors #TLRSignaling #NowOnline #JPhysiolSci
October 21, 2026 at 12:12 AM
Inside Day Three Of The Oral Powder Stack On Autism Models. Do You Believe It?

Sources:
pubmed.ncbi.nlm.nih.gov/28460574/

#NSI189 #J147 #Neurogenesis #ResearchUpdates #SynapticPlasticity #PreclinicalResearch #NeuralRemodeling
October 18, 2026 at 4:21 PM
October 13, 2026 at 7:06 PM
Can Trofinetide End Repetitive Motor Loops in Autism?

Source: pmc.ncbi.nlm.nih.gov/articles/PMC...
Evaluating Trofinetide peptide reversing severe repetitive motor loops and physical freeze states. #Trofinetide #BrainPlasticity #Neurogenesis #SynapticPlasticity #BrainRepair #Neuroscience
October 13, 2026 at 9:20 PM
Did NSI-189 Just Fully Rescue Electrical Signaling Severely Autistic Research Subjects?

Source: pubmed.ncbi.nlm.nih.gov/31492662/
Source: pubmed.ncbi.nlm.nih.gov/30408487/

#SynapticPlasticity #Neurobiology #BrainWiring #autismspeaks #peptides
October 12, 2026 at 2:06 PM
Did Researchers Just Rebuild Essential Learning Circuits In Severe Autism Subjects?

Source: pubmed.ncbi.nlm.nih.gov/31492662/

Preclinical data shows NSI-189 doubles mature mushroom spine hardware in severe autism subjects. #SpineDensity #SynapticPlasticity #NeuralCircuits #Neurobiology #autism
October 11, 2026 at 9:57 PM
October 10, 2026 at 12:45 AM
Important boundary: these are simulation outputs under assumed pathway convergence and exploratory parameters—not evidence that IPLs exist in vivo or encode subjective memory. Society for Neuroscience #Memory #SynapticPlasticity #ComputationalNeuroscience #AssociativeLearning
October 9, 2026 at 10:17 AM
October 6, 2026 at 12:50 PM
October 4, 2026 at 5:09 PM
Last week, we had the pleasure of hosting Dr. Ryohei Yasuda for an insightful seminar on “Decoding neuronal biochemical signaling for synaptic plasticity!” 🧠🔬

Thanks to Dr. Yasuda for the incredible talk and to Haiyan He for hosting!

#Neuroscience #Research #SynapticPlasticity
September 25, 2026 at 4:13 PM
The Molecule Destroying Traditional Alzheimer's Treatments

Preclinical data shows J147 thickens dendritic spine density, outperforming Donepezil in cognitive research on animals only.

#neuroscience #brainhealth #preclinicalresearch #synapticplasticity #cellularbiology
September 9, 2026 at 6:54 PM
Is This Breakthrough Autism Molecule Threatening Every Traditional Protocol? #NSI189 #Neurogenesis #AutismResearch #SynapticPlasticity #Biohacking
August 22, 2026 at 11:01 PM
Decorating #MXene with the N-fused organic #semiconductor CBIN overcomes its metallic behavior to enable stable bipolar #memristive switching with low voltages and #synapticplasticity, expanding MXene #memristors toward #neuromorphic computing.

#IJEM: doi.org/10.1088/2631...
December 5, 2025 at 12:30 PM
#Electroacupuncture-induced activation of #serotonergic neurons in the dorsal raphe nucleus alleviates #CognitiveDysfunction in APP/PS1 mice, by activating #glutamatergic neurons and enhancing #SynapticPlasticity. #AlzheimersDisease #medsky

#MostDownloaded: link.springer.com/article/10.1...
August 2, 2025 at 2:01 PM
New in #ScienceSignaling 👉Importin β1 has an unexpected role in presynaptic long-term plasticity and spatial memory, by regulating local protein synthesis at hippocampal synapses.

#neuroscience #cellbiology #synapticplasticity #memory

www.science.org/doi/10.1126/...
February 3, 2026 at 4:30 PM
It’s conference season! We're just back from AXON2025 & Discovery on Target where we: shared progress on antibodies to 50+ neuronal targets, discussed strategies for #membraneprotein and #GPCR discovery & met determined researchers in #braindevelopment #synapticplasticity #antibodydiscovery & more.
September 26, 2025 at 5:04 PM
Busy September 17-19? You should be! Join us at #AXON2025 to share research on #synapticplasticity, #braindevelopment, #neuralcircuitry, and more. Early bird registration ends May 1 🦤

#neuroscience #neuroskyence #axonguidance
AXON2025 Meeting Rotterdam
Topics Synaptic plasticity Local translation Neuron-glia interactions Brain development and evolution Human models Single cell profiling Advanced imaging technology And more!
axon2025.com
April 15, 2025 at 5:04 PM
How can cortical circuits adjust inhibition without losing temporal precision?

We discuss how tuning excitatory input onto PV interneurons may regulate inhibitory tone while preserving circuit stability.

doi.org/10.3389/fnsy...

#synapticplasticity #interneurons #aging #alzheimer #criticalperiod
Frontiers | Tuning excitatory input to fast-spiking parvalbumin-positive interneurons: a lever for plasticity and hyperexcitability across the lifespan
Experience reshapes cortical circuits, yet plasticity is tightly gated—high during early critical periods and increasingly constrained with maturation. Later...
doi.org
May 11, 2026 at 1:00 AM
7/
Huge credit to the very talented grad students Airi Watanabe and Connie Guo for the enormous amount of work behind this review. Very proud of what they put together. #Neuroscience #Astrocytes #SynapticPlasticity #LearningAndMemory
May 25, 2026 at 7:01 PM