#VASOPRESSORS
“patient remains on vasopressors, hemodynamically stable”

“pumps continue to remove incoming seawater, hull intact”
March 28, 2025 at 5:44 PM
My unit is full of people dying from social neglect. Treating injustice and disparity with ventilators and vasopressors is like rearranging deck chairs on the Titanic. I could keep doing it if I knew that our provincial government was trying to fix the underlying problems.
November 15, 2024 at 2:36 AM
Like invoking the vasopressors and inotrope crowd. Or hypoxia and hypoxemia.
January 20, 2025 at 3:59 PM
Same.

Infants on ventilators…
Athletic teens with MIS-C requiring vasopressors while their heart function looks like a huge anterior wall MI…
long COVID cases impacting school and other daily activities…

My family will continue to get vaccinated and I’ll continue recommending it to my patients
I know that people have a lot of thoughts about #COVID vaccines in kids but as someone who cared for previously healthy kids who had really bad outcomes, I will be vaccinating my kids every chance I can get.
May 27, 2025 at 8:15 PM
Periodic reminder that for most people with vasodilatory shock we should be targeting a MAP > 60 mmHg (not 65).

A lower MAP goal was associated with a shortened duration of vasopressors & possibly reduced mortality.

With vasopressors, less is truly more.

jamanetwork.com/journals/jam...
February 23, 2025 at 11:21 PM
December 23, 2024 at 7:42 PM
Among adults with septic shock, the use of restricted fluids and early vasopressors did not result in more days alive and out of the hospital through day 90 than the use of liberal fluids and later vasopressors. Full ARISE FLUIDS trial results: https://nej.md/3PVdwIp

#CCR26
June 11, 2026 at 8:20 AM
creating an updated/merged chapter on shock & vasoactives

any good pearls or recent references on vasopressors & inotropes?

also shoutout to @eddyjoemd.bsky.social, his handbook on vasopressors & inotropes is pretty great #EMIMCC
a cartoon character from south park says " oh man " while sitting in a chair
ALT: a cartoon character from south park says " oh man " while sitting in a chair
media.tenor.com
January 22, 2025 at 12:21 PM
Pretty embarrassing that a major EM textbook lists Milrinone & Dobutamine as vasopressors.
December 28, 2024 at 8:28 PM
6/ HPS in the Americas carries a CFR of up to 50%. No antiviral works against it. Severely ill patients need mechanical ventilation, vasopressors, and sometimes ECMO, a machine that oxygenates blood when lungs fail. That's the level of care the Johannesburg ICU patient requires.
May 5, 2026 at 12:08 PM
December 3, 2024 at 3:29 AM
New RCT: Avoiding A-line in shock didn't affect mortality (trend towards *reduction*) & decreased line complications

They avoided A-lines despite patients requiring pretty substantial doses of vasopressors

Very #zentensivist

Don't need to rush to an A-line

www.nejm.org/doi/full/10.... #EMIMCC
October 29, 2025 at 3:19 PM
It feels like all one big tease. To have hope and a miracle happen only to have one of the side effects of vasopressors take your hope away.
September 21, 2025 at 4:09 AM
Such an important teaching point. In patients who respond poorly to vasopressors, always question whether the blood pressure measurement you are targeting is actually representative. #emimcc #cardiosky
ICU Snapshots:

Walking from room to room in the ICU, you see this on the monitor of a 60 yo female patient admitted the previous night with severe community-acquired pneumonia & what you were told was "refractory" septic/cardiogenic shock. Arterial line was in the R fem artery:
September 21, 2025 at 10:55 AM
It's that wonderful time of year when new residents are joining the ICU team!

Here are a few of my favorite @criticalcaretime.bsky.social infographics to help you understand key concepts:
⚡️Undifferentiated shock
💉 Vasopressors
😮‍💨 The physiologically difficult airway &
🧪 Metabolic acidosis
June 30, 2025 at 2:09 AM
Septic shock requiring three or more vasopressors was associated with 57.6% in-hospital mortality. (That's it?!?!? - seems low)... 342 ICUs. Free article.

#emimcc #FOAMed

pubmed.ncbi.nlm.nih.gov/39529908/
Septic Shock Requiring Three Vasopressors: Patient Demographics and Outcomes - PubMed
Septic shock requiring three vasopressors is associated with exceptionally high mortality. Knowledge of patients at highest risk of mortality in this population may inform management and expectations ...
pubmed.ncbi.nlm.nih.gov
November 16, 2024 at 8:27 PM
Totally agree with you Seg
Less MAP
Less fluids
Less vasopressors
And more patience
February 7, 2026 at 7:34 AM
Keeping with the ICU theme, here is an infographic by The Intern At Work on vasopressors. Quick and easy to digest.

#ICU #medtwitter. #medsky. #vasopressors.
November 14, 2024 at 4:50 PM
He looks exactly like I would imagine I looked explaining that they're "vasopressors, not inotropes".

It was a bad time, ok?
November 16, 2024 at 9:01 PM
Inotropes/Vasopressors, sedation, oxygen: the holy trinity of ICU.

With fluids the mercenaries, willing to switch sides without warning
Fluids, Insulin, Antibiotics: the holy trinity of medicine
December 13, 2024 at 4:42 PM
Noradrenaline, metaraminol, phenylephrine or vasopressin?

This ovine cardiopulmonary bypass experiment suggests that the choice of vasopressors may affect renal oxygenation.

#AnSky #MedSky
doi.org
November 24, 2025 at 3:01 PM
As an ethnic minority in the UK where there is a rise in right-wing populism, I'd like to stake my credentials as a citizen on the basis that when asked what emergency drugs I draw up for anaesthesia, rather than picking vasopressors or muscle relaxants, I said "tea".
July 12, 2025 at 12:14 PM
Kinda unfair that in a whole category called “vasopressors” the one actually called “vasopressin” is only the number 2 choice of vasopressor.
April 23, 2024 at 3:40 PM
BP monitor looks okay, but patient is mottled. Don't blindly escalate vasopressors without assessing volume status. Lift legs, check cap refill, consider tamponade. https://bexyhub.in
BP monitor looks okay, but patient is mottled. Don't blindly escalate vasopressors without assessing volume status. Lift legs, check cap refill, consider tamponade. https://bexyhub.in
BP monitor looks okay, but patient is mottled. Don't blindly escalate vasopressors without assessing volume status. Lift legs, check cap refill, consider tamponade. https://bexyhub.in
bexyhub.in
September 24, 2026 at 3:06 AM
🔥The ARISE FLUIDS RCT
Among adults with septic shock, Restricted fluids + early vasopressors did not result in more days alive & out of the hospital through day 90 than liberal fluids + later vasopressors
Pulmonary edema (0.6% in the vasopressor group vs. 5.0% in the fluids group; P<0.001). #idsky
nejm.org NEJM.org @nejm.org · Jun 11
Among adults with septic shock, the use of restricted fluids and early vasopressors did not result in more days alive and out of the hospital through day 90 than the use of liberal fluids and later vasopressors. Full ARISE FLUIDS trial results: https://nej.md/3PVdwIp

#CCR26
June 11, 2026 at 10:35 AM