Check out our recent work 'Annexin- and calcium-regulated priming of legume root cells for endosymbiotic infection' in Nature Communications rdcu.be/d2Aye
Annexin- and calcium-regulated priming of legume root cells for endosymbiotic infection
Nature Communications - This study describes ultrastructural changes and cell-specific calcium responses that accompany cytoplasmic bridge formation in legume root cells committed to symbiotic...
rdcu.be
December 10, 2024 at 4:44 PM
Check out our recent work 'Annexin- and calcium-regulated priming of legume root cells for endosymbiotic infection' in Nature Communications rdcu.be/d2Aye
Madisonians, rally the troops! It’s time to go annexin’ 🤠
Shorewood Hills Trustees tonight of to great start. They have no clerk because she is away on bereavement leave. They just have the administrator left. They are trying to figure out what should be on the agenda, and trying to figure out the Roberts Rules for that. Looks like Facebook broadcast down
March 17, 2026 at 11:20 PM
Madisonians, rally the troops! It’s time to go annexin’ 🤠
My choice this week in @science.org
The ALS- and FTD-associated proteins annexin A11 and CHMP2B act sequentially in plasma membrane repair
www.cell.com/developmenta...
The ALS- and FTD-associated proteins annexin A11 and CHMP2B act sequentially in plasma membrane repair
www.cell.com/developmenta...
August 14, 2026 at 4:37 PM
My choice this week in @science.org
The ALS- and FTD-associated proteins annexin A11 and CHMP2B act sequentially in plasma membrane repair
www.cell.com/developmenta...
The ALS- and FTD-associated proteins annexin A11 and CHMP2B act sequentially in plasma membrane repair
www.cell.com/developmenta...
We’ve engineered stable cell systems to induce lipid scrambling of the plasma membrane with active forms of TMEM16F. Scrambling alone causes vesiculation (🔵TMEM16F-active; 🟠PS/Annexin V). Let us know if you want to try the cells out. Preprint: www.biorxiv.org/content/10.1...
May 14, 2025 at 10:46 PM
We’ve engineered stable cell systems to induce lipid scrambling of the plasma membrane with active forms of TMEM16F. Scrambling alone causes vesiculation (🔵TMEM16F-active; 🟠PS/Annexin V). Let us know if you want to try the cells out. Preprint: www.biorxiv.org/content/10.1...
Annexin A7 enhances TIA1 axonal trafficking to counteract pathological aggregation in neurons
Tong Wang and coworkers
www.embopress.org/doi/full/10....
Tong Wang and coworkers
www.embopress.org/doi/full/10....
November 5, 2025 at 6:45 AM
Annexin A7 enhances TIA1 axonal trafficking to counteract pathological aggregation in neurons
Tong Wang and coworkers
www.embopress.org/doi/full/10....
Tong Wang and coworkers
www.embopress.org/doi/full/10....
Can you spot the troubles with these flow cytometry panels?
#ImageForensics
#ImageForensics
December 31, 2024 at 12:23 AM
Can you spot the troubles with these flow cytometry panels?
#ImageForensics
#ImageForensics
Real time view of High Speed AFM data capture at 35fps. This is a 20nm x 20nm area showing an annexin V trimer rotating within a lattice. (Data from 2022)
#AFM #microscopy
#AFM #microscopy
November 11, 2024 at 7:49 PM
Real time view of High Speed AFM data capture at 35fps. This is a 20nm x 20nm area showing an annexin V trimer rotating within a lattice. (Data from 2022)
#AFM #microscopy
#AFM #microscopy
University of Western Ontario researchers found annexin A5 binds both the SARS-CoV-2 Spike protein and the ACE2 receptor.
By blocking the virus at both sides of entry, it reduced viral burden and improved infected cell survival.
www.nature.com/articles/s41...
By blocking the virus at both sides of entry, it reduced viral burden and improved infected cell survival.
www.nature.com/articles/s41...
Dual engagement of Spike and ACE2 by annexin A5 contributes to pleiotropic SARS-CoV-2 inhibition - Scientific Reports
Scientific Reports - Dual engagement of Spike and ACE2 by annexin A5 contributes to pleiotropic SARS-CoV-2 inhibition
www.nature.com
June 21, 2026 at 7:19 PM
University of Western Ontario researchers found annexin A5 binds both the SARS-CoV-2 Spike protein and the ACE2 receptor.
By blocking the virus at both sides of entry, it reduced viral burden and improved infected cell survival.
www.nature.com/articles/s41...
By blocking the virus at both sides of entry, it reduced viral burden and improved infected cell survival.
www.nature.com/articles/s41...
📈Read one of our editor picks for September
Gatto & coll from Mayo clinic investigated the origins of off-target tau-PET binding in frontotemporal lobar degeneration, esp the contributions of TDP-43 and annexin A11. 🧠
www.thelancet.com/journals/lan...
#neurosky
Gatto & coll from Mayo clinic investigated the origins of off-target tau-PET binding in frontotemporal lobar degeneration, esp the contributions of TDP-43 and annexin A11. 🧠
www.thelancet.com/journals/lan...
#neurosky
Investigation of TDP-43 and annexin A11 contributions to off-target tau-PET binding in frontotemporal lobar degeneration: a retrospective, observational study
Flortaucipir uptake in FTLD-TDP, particularly type C, could reflect off-target binding
to phosphorylated TDP-43 and ANXA11 aggregates in limbic regions rather than tau pathology
alone; consequently, t...
www.thelancet.com
October 6, 2026 at 2:22 PM
📈Read one of our editor picks for September
Gatto & coll from Mayo clinic investigated the origins of off-target tau-PET binding in frontotemporal lobar degeneration, esp the contributions of TDP-43 and annexin A11. 🧠
www.thelancet.com/journals/lan...
#neurosky
Gatto & coll from Mayo clinic investigated the origins of off-target tau-PET binding in frontotemporal lobar degeneration, esp the contributions of TDP-43 and annexin A11. 🧠
www.thelancet.com/journals/lan...
#neurosky
Sorcin couples Annexin A11 recruitment to ESCRT-III assembly for plasma membrane repair | PNAS www.pnas.org/doi/10.1073/...
Sorcin couples Annexin A11 recruitment to ESCRT-III assembly for plasma membrane repair | PNAS
The absence of a cell wall affords animal cells diverse functionality at the cost
of acute sensitization to plasma membrane (PM) damage. Thus, anim...
www.pnas.org
August 11, 2026 at 3:44 PM
Sorcin couples Annexin A11 recruitment to ESCRT-III assembly for plasma membrane repair | PNAS www.pnas.org/doi/10.1073/...
The authors included RRIDs in their in Scientific Reports paper! We value the author's support of reproducibility. #methodsmatter #accelerateopenscience #STMpublishing
Dual engagement of Spike and ACE2 by annexin A5 contributes to pleiotropic SARS-CoV-2 inhibition - Scientific Reports
Read the full paper: Dual engagement of Spike and ACE2 by annexin A5 contributes to pleiotropic SARS-CoV-2 inhibition
doi.org
October 9, 2026 at 7:03 AM
The authors included RRIDs in their in Scientific Reports paper! We value the author's support of reproducibility. #methodsmatter #accelerateopenscience #STMpublishing
The ALS- and FTD-associated proteins annexin A11 and CHMP2B act sequentially in plasma membrane repair: Developmental Cell www.cell.com/developmenta...
The ALS- and FTD-associated proteins annexin A11 and CHMP2B act sequentially in plasma membrane repair
Heffner et al. show that ANXA11 and CHMP2B, proteins encoded by ALS- and FTD-risk
genes, are sequentially recruited to sites of plasma membrane damage. Membrane repair
involves ANXA11-positive plug fo...
www.cell.com
June 29, 2026 at 9:58 PM
The ALS- and FTD-associated proteins annexin A11 and CHMP2B act sequentially in plasma membrane repair: Developmental Cell www.cell.com/developmenta...
I’m happy to share that my latest PhD work is published in
@embojournal.org
! We demonstrate a fundamental role for Annexin A5 in regulating mitochondrial calcium signaling and apoptosis. www.embopress.org/doi/full/10....
@embojournal.org
! We demonstrate a fundamental role for Annexin A5 in regulating mitochondrial calcium signaling and apoptosis. www.embopress.org/doi/full/10....
May 12, 2025 at 8:14 AM
I’m happy to share that my latest PhD work is published in
@embojournal.org
! We demonstrate a fundamental role for Annexin A5 in regulating mitochondrial calcium signaling and apoptosis. www.embopress.org/doi/full/10....
@embojournal.org
! We demonstrate a fundamental role for Annexin A5 in regulating mitochondrial calcium signaling and apoptosis. www.embopress.org/doi/full/10....
@drnatsampaio.bsky.social from @hudsonresearch.bsky.social taking us through how annexin A2 mediates RIG-I like receptor responses to viral infection. A really great story! 🦠 #lorneiandi
February 19, 2026 at 1:04 AM
@drnatsampaio.bsky.social from @hudsonresearch.bsky.social taking us through how annexin A2 mediates RIG-I like receptor responses to viral infection. A really great story! 🦠 #lorneiandi
Great collaboration with @adrianisaacs.bsky.social showing coordinated role for FTD/ALS proteins CHMP2B and ANXA11 in membrane repair! Well done Catherine Heffner, Georgina Starling, Lorian Cobra Straker and Pippa Hawes! @crick.ac.uk, @ukdri.ac.uk, @kingslsm.bsky.social. www.cell.com/developmenta...
The ALS- and FTD-associated proteins annexin A11 and CHMP2B act sequentially in plasma membrane repair
Heffner et al. show that ANXA11 and CHMP2B, proteins encoded by ALS- and FTD-risk
genes, are sequentially recruited to sites of plasma membrane damage. Membrane repair
involves ANXA11-positive plug fo...
www.cell.com
June 25, 2026 at 9:11 PM
Great collaboration with @adrianisaacs.bsky.social showing coordinated role for FTD/ALS proteins CHMP2B and ANXA11 in membrane repair! Well done Catherine Heffner, Georgina Starling, Lorian Cobra Straker and Pippa Hawes! @crick.ac.uk, @ukdri.ac.uk, @kingslsm.bsky.social. www.cell.com/developmenta...
ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes!
Annexin A11 tethers RNP granules to membranes in a Ca2+ dependent manner.
@abelljonny.bsky.social, @michael-e-ward.bsky.social, et al.
www.nature.com/articles/s41...
Annexin A11 tethers RNP granules to membranes in a Ca2+ dependent manner.
@abelljonny.bsky.social, @michael-e-ward.bsky.social, et al.
www.nature.com/articles/s41...
ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes - Nature Communications
Nixon-Abell et al. show that ANXA11 condensation on lysosomal membranes causes a coupled phase transition of the underlying lipids and mechanical stiffening of the overall ensemble involved in RNP gra...
www.nature.com
March 23, 2025 at 9:25 AM
ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes!
Annexin A11 tethers RNP granules to membranes in a Ca2+ dependent manner.
@abelljonny.bsky.social, @michael-e-ward.bsky.social, et al.
www.nature.com/articles/s41...
Annexin A11 tethers RNP granules to membranes in a Ca2+ dependent manner.
@abelljonny.bsky.social, @michael-e-ward.bsky.social, et al.
www.nature.com/articles/s41...
Calpains orchestrate secretion of annexin-containing microvesicles during membrane repair, say Justin Krish Williams, Randy Schekman et al. @ucberkeleyofficial.bsky.social rupress.org/jcb/article/...
#EVs #Exosomes
#EVs #Exosomes
May 23, 2025 at 2:22 PM
Calpains orchestrate secretion of annexin-containing microvesicles during membrane repair, say Justin Krish Williams, Randy Schekman et al. @ucberkeleyofficial.bsky.social rupress.org/jcb/article/...
#EVs #Exosomes
#EVs #Exosomes
Leikina, Kozlov, Chernomordik et al. propose a novel signaling pathway linking together intracellular Ca²⁺ signaling, #phosphatidylserine exposure, #annexin A5 binding and #actin cortex detachment that facilitates #osteoclast fusion. rupress.org/jcb/article/...
#Membrane #lipid #CellSignaling
#Membrane #lipid #CellSignaling
December 2, 2025 at 8:15 PM
Leikina, Kozlov, Chernomordik et al. propose a novel signaling pathway linking together intracellular Ca²⁺ signaling, #phosphatidylserine exposure, #annexin A5 binding and #actin cortex detachment that facilitates #osteoclast fusion. rupress.org/jcb/article/...
#Membrane #lipid #CellSignaling
#Membrane #lipid #CellSignaling
The annexin A1 mimetic peptide Ac2-26 promotes inflammation-resolution and stimulates skeletal muscle regeneration in the mdx mouse model of Duchenne muscular dystrophy https://www.biorxiv.org/content/10.64898/2026.10.05.756885v1
October 6, 2026 at 12:30 PM
The annexin A1 mimetic peptide Ac2-26 promotes inflammation-resolution and stimulates skeletal muscle regeneration in the mdx mouse model of Duchenne muscular dystrophy https://www.biorxiv.org/content/10.64898/2026.10.05.756885v1
Annexin gene family in Spirometra mansoni (Cestoda: Diphyllobothriidae) and its phylogenetic pattern among Platyhelminthes of medical interest
doi.org/10.1051/para...
doi.org/10.1051/para...
December 15, 2024 at 2:35 PM
Annexin gene family in Spirometra mansoni (Cestoda: Diphyllobothriidae) and its phylogenetic pattern among Platyhelminthes of medical interest
doi.org/10.1051/para...
doi.org/10.1051/para...
The annexin A1 mimetic peptide Ac2-26 promotes inflammation-resolution and stimulates skeletal muscle regeneration in the mdx mouse model of Duchenne muscular dystrophy https://www.biorxiv.org/content/10.64898/2026.10.05.756885v1
October 6, 2026 at 12:30 PM
The annexin A1 mimetic peptide Ac2-26 promotes inflammation-resolution and stimulates skeletal muscle regeneration in the mdx mouse model of Duchenne muscular dystrophy https://www.biorxiv.org/content/10.64898/2026.10.05.756885v1
Annexin A11 and TDP-43: core players in neurodegeneration pubmed.ncbi.nlm.nih.gov/42414528/ #cryoem
July 8, 2026 at 11:47 AM
Annexin A11 and TDP-43: core players in neurodegeneration pubmed.ncbi.nlm.nih.gov/42414528/ #cryoem
I unabashedly love Halloween ads from research companies.
October 26, 2025 at 1:07 PM
I unabashedly love Halloween ads from research companies.