Those amazing #phages 🦠 figured out 5mC chemistry before we did:
📄 Out today in @MolecularCell we describe a 5mC-selective #deaminase family in environmental phage genomes with broad applications for #5base #sequencing
#epigenetics #DNAmethylation #genomics #NGS 🧬🧪
www.cell.com/molecular-ce...
📄 Out today in @MolecularCell we describe a 5mC-selective #deaminase family in environmental phage genomes with broad applications for #5base #sequencing
#epigenetics #DNAmethylation #genomics #NGS 🧬🧪
www.cell.com/molecular-ce...
April 20, 2026 at 6:19 AM
Those amazing #phages 🦠 figured out 5mC chemistry before we did:
📄 Out today in @MolecularCell we describe a 5mC-selective #deaminase family in environmental phage genomes with broad applications for #5base #sequencing
#epigenetics #DNAmethylation #genomics #NGS 🧬🧪
www.cell.com/molecular-ce...
📄 Out today in @MolecularCell we describe a 5mC-selective #deaminase family in environmental phage genomes with broad applications for #5base #sequencing
#epigenetics #DNAmethylation #genomics #NGS 🧬🧪
www.cell.com/molecular-ce...
Check out the latest Reviews and Perspectives from experts in RNA biology in this joint collection from @CellChemBiol and @MolecularCell http://dlvr.it/TGwFkr
Molecular mechanisms in RNA biology: Cell Press
dlvr.it
December 20, 2024 at 8:16 PM
Check out the latest Reviews and Perspectives from experts in RNA biology in this joint collection from @CellChemBiol and @MolecularCell http://dlvr.it/TGwFkr
We’ve worked out how the molecular machines that create acidic compartments can recruit autophagy (self-eating) machinery when they can’t maintain a pH gradient. We are really pleased with this discovery, out in @MolecularCell cell.com/molecular-cell…. 1/16
https://cell.com/molecular-cell…
August 8, 2024 at 11:30 PM
We’ve worked out how the molecular machines that create acidic compartments can recruit autophagy (self-eating) machinery when they can’t maintain a pH gradient. We are really pleased with this discovery, out in @MolecularCell cell.com/molecular-cell…. 1/16
Excited to see this work on the cover of #MolecularCell. A massive, open #cryoEM #cryoET dataset capturing molecular organization inside intact cells, pushing what’s possible for #visualproteomics, method development, and computational reuse. Congratulations to the authors.
ter.li/of4cgh
ter.li/of4cgh
January 16, 2026 at 10:03 AM
Excited to see this work on the cover of #MolecularCell. A massive, open #cryoEM #cryoET dataset capturing molecular organization inside intact cells, pushing what’s possible for #visualproteomics, method development, and computational reuse. Congratulations to the authors.
ter.li/of4cgh
ter.li/of4cgh
On the cover #MolecularCell. In this issue Acharya and Demetriades show how #mTORC1 🎈activation mediates its own release from the #lysosomes 🪐🌎. It was my pleasure to bring to life the grand idea from Aishwarya and Costas!
November 21, 2024 at 6:06 PM
On the cover #MolecularCell. In this issue Acharya and Demetriades show how #mTORC1 🎈activation mediates its own release from the #lysosomes 🪐🌎. It was my pleasure to bring to life the grand idea from Aishwarya and Costas!
I’m thrilled to see my artwork on the #cover of #MolecularCell!
A study by @imilenkovic.bsky.social et al used epitranscriptomic rRNA fingerprinting to identify tissue-of-origin and tumor-specific signatures. @NovoaLab @crg.eu
#sciart #scicomm #science #cancerresearch
A study by @imilenkovic.bsky.social et al used epitranscriptomic rRNA fingerprinting to identify tissue-of-origin and tumor-specific signatures. @NovoaLab @crg.eu
#sciart #scicomm #science #cancerresearch
January 7, 2025 at 4:46 PM
I’m thrilled to see my artwork on the #cover of #MolecularCell!
A study by @imilenkovic.bsky.social et al used epitranscriptomic rRNA fingerprinting to identify tissue-of-origin and tumor-specific signatures. @NovoaLab @crg.eu
#sciart #scicomm #science #cancerresearch
A study by @imilenkovic.bsky.social et al used epitranscriptomic rRNA fingerprinting to identify tissue-of-origin and tumor-specific signatures. @NovoaLab @crg.eu
#sciart #scicomm #science #cancerresearch
🔬Check out this recent spotlight in #MolecularCell, co-authored by Rory Whelan
Ferran José Duran & @crismayorruiz.bsky.social— Mutations that stick: Unexpected discovery of molecular glue mimicry👇
➡️ https://f.mtr.cool/zbljytwpcx
#ChemBio #MolecularGlue #MolecularGlues
🧪
Ferran José Duran & @crismayorruiz.bsky.social— Mutations that stick: Unexpected discovery of molecular glue mimicry👇
➡️ https://f.mtr.cool/zbljytwpcx
#ChemBio #MolecularGlue #MolecularGlues
🧪
April 23, 2025 at 7:31 AM
🔬Check out this recent spotlight in #MolecularCell, co-authored by Rory Whelan
Ferran José Duran & @crismayorruiz.bsky.social— Mutations that stick: Unexpected discovery of molecular glue mimicry👇
➡️ https://f.mtr.cool/zbljytwpcx
#ChemBio #MolecularGlue #MolecularGlues
🧪
Ferran José Duran & @crismayorruiz.bsky.social— Mutations that stick: Unexpected discovery of molecular glue mimicry👇
➡️ https://f.mtr.cool/zbljytwpcx
#ChemBio #MolecularGlue #MolecularGlues
🧪
🚨 Check out our latest review in #MolecularCell!
We discuss how formaldehyde, a toxic metabolic by-product, threatens genome stability and disrupts cellular homeostasis.
👏 Outstanding work by our talented PhD Std #MartaValverde @carrerasijc.bsky.social
👉📰
authors.elsevier.com/a/1lDFm3vVUP...
We discuss how formaldehyde, a toxic metabolic by-product, threatens genome stability and disrupts cellular homeostasis.
👏 Outstanding work by our talented PhD Std #MartaValverde @carrerasijc.bsky.social
👉📰
authors.elsevier.com/a/1lDFm3vVUP...
June 5, 2025 at 4:58 PM
🚨 Check out our latest review in #MolecularCell!
We discuss how formaldehyde, a toxic metabolic by-product, threatens genome stability and disrupts cellular homeostasis.
👏 Outstanding work by our talented PhD Std #MartaValverde @carrerasijc.bsky.social
👉📰
authors.elsevier.com/a/1lDFm3vVUP...
We discuss how formaldehyde, a toxic metabolic by-product, threatens genome stability and disrupts cellular homeostasis.
👏 Outstanding work by our talented PhD Std #MartaValverde @carrerasijc.bsky.social
👉📰
authors.elsevier.com/a/1lDFm3vVUP...
This study @MolecularCell beautifully demonstrated
hyper- and hypo-osmotic stress constricts and dilates, respectively, diameters of nuclear pore complexes (NPCs) at inner ring.
Nuclear pore permeability and fluid flow are modulated by its dilation state
www.sciencedirect.com/science/arti...
hyper- and hypo-osmotic stress constricts and dilates, respectively, diameters of nuclear pore complexes (NPCs) at inner ring.
Nuclear pore permeability and fluid flow are modulated by its dilation state
www.sciencedirect.com/science/arti...
January 12, 2025 at 7:45 PM
This study @MolecularCell beautifully demonstrated
hyper- and hypo-osmotic stress constricts and dilates, respectively, diameters of nuclear pore complexes (NPCs) at inner ring.
Nuclear pore permeability and fluid flow are modulated by its dilation state
www.sciencedirect.com/science/arti...
hyper- and hypo-osmotic stress constricts and dilates, respectively, diameters of nuclear pore complexes (NPCs) at inner ring.
Nuclear pore permeability and fluid flow are modulated by its dilation state
www.sciencedirect.com/science/arti...
Really enjoyed reading in #MolecularCell "RNA sensing induced by chromosome missegregation augments anti-tumor immunity"
They found dsRNA sensing is equally important in the #interferon response to micronuclei induced by inhibition of spindle assembly.
www.sciencedirect.com/science/arti...
They found dsRNA sensing is equally important in the #interferon response to micronuclei induced by inhibition of spindle assembly.
www.sciencedirect.com/science/arti...
www.sciencedirect.com
January 20, 2025 at 9:57 PM
Really enjoyed reading in #MolecularCell "RNA sensing induced by chromosome missegregation augments anti-tumor immunity"
They found dsRNA sensing is equally important in the #interferon response to micronuclei induced by inhibition of spindle assembly.
www.sciencedirect.com/science/arti...
They found dsRNA sensing is equally important in the #interferon response to micronuclei induced by inhibition of spindle assembly.
www.sciencedirect.com/science/arti...
Very excited to share our new paper out now in
@MolecularCell. We show how U1 snRNP -a well-known splicing factor- regulates the activity of alternative promoters in human cells www.cell.com/molecular-ce...
@MolecularCell. We show how U1 snRNP -a well-known splicing factor- regulates the activity of alternative promoters in human cells www.cell.com/molecular-ce...
U1 snRNP regulates alternative promoter activity by inhibiting premature polyadenylation
Kim et al. uncover a role for U1 snRNP in regulating internal promoter activity. Beyond
its canonical role in splicing, U1 snRNP suppresses premature polyadenylation, enabling
upstream transcription t...
www.cell.com
May 16, 2025 at 3:35 PM
Very excited to share our new paper out now in
@MolecularCell. We show how U1 snRNP -a well-known splicing factor- regulates the activity of alternative promoters in human cells www.cell.com/molecular-ce...
@MolecularCell. We show how U1 snRNP -a well-known splicing factor- regulates the activity of alternative promoters in human cells www.cell.com/molecular-ce...
🚀 Thrilled to share our latest review: "Uracil-induced replication stress drives mutations, genome instability, anti-cancer treatment efficacy, and resistance"
👉 doi.org/10.1016/j.mo...
#CancerResearch #DNARepair #ReplicationStress #MolecularCell #GenomicInstability #CancerTherapy #Uracil
👉 doi.org/10.1016/j.mo...
#CancerResearch #DNARepair #ReplicationStress #MolecularCell #GenomicInstability #CancerTherapy #Uracil
Redirecting
doi.org
May 20, 2025 at 8:07 AM
🚀 Thrilled to share our latest review: "Uracil-induced replication stress drives mutations, genome instability, anti-cancer treatment efficacy, and resistance"
👉 doi.org/10.1016/j.mo...
#CancerResearch #DNARepair #ReplicationStress #MolecularCell #GenomicInstability #CancerTherapy #Uracil
👉 doi.org/10.1016/j.mo...
#CancerResearch #DNARepair #ReplicationStress #MolecularCell #GenomicInstability #CancerTherapy #Uracil
Happy to share our design was selected as cover art
in MolecularCell🎉
This depicts the moonlighting function of PRDX6 carrying rocks of selenium, named after the goddes of moon Selene.
www.cell.com/molecular-ce...
in MolecularCell🎉
This depicts the moonlighting function of PRDX6 carrying rocks of selenium, named after the goddes of moon Selene.
www.cell.com/molecular-ce...
December 6, 2024 at 6:17 AM
Happy to share our design was selected as cover art
in MolecularCell🎉
This depicts the moonlighting function of PRDX6 carrying rocks of selenium, named after the goddes of moon Selene.
www.cell.com/molecular-ce...
in MolecularCell🎉
This depicts the moonlighting function of PRDX6 carrying rocks of selenium, named after the goddes of moon Selene.
www.cell.com/molecular-ce...
Learn more about Molecular Mechanisms in RNA Biology with this joint collection of the latest Reviews and Perspectives from @CellChemBiol and @MolecularCell http://dlvr.it/TGyn8C
Molecular mechanisms in RNA biology: Cell Press
dlvr.it
December 23, 2024 at 5:31 PM
Learn more about Molecular Mechanisms in RNA Biology with this joint collection of the latest Reviews and Perspectives from @CellChemBiol and @MolecularCell http://dlvr.it/TGyn8C
Learn more about Molecular Mechanisms in RNA Biology with this joint collection of the latest Reviews and Perspectives from @CellChemBiol and @MolecularCell http://dlvr.it/TH4dtW
Molecular mechanisms in RNA biology: Cell Press
dlvr.it
December 30, 2024 at 5:31 PM
Learn more about Molecular Mechanisms in RNA Biology with this joint collection of the latest Reviews and Perspectives from @CellChemBiol and @MolecularCell http://dlvr.it/TH4dtW
Congrats to Jenny and Liam on our Prevew in Molecular Cell on the excellent paper by Yaqin Deng, Jin Ye et al in the same issue describing a new protection mechanism against #ferroptosis by #DHA — Here is a free download: authors.elsevier.com/a/1loAH3vVUP... @MolecularCell @Columbia
September 18, 2025 at 3:22 PM
Congrats to Jenny and Liam on our Prevew in Molecular Cell on the excellent paper by Yaqin Deng, Jin Ye et al in the same issue describing a new protection mechanism against #ferroptosis by #DHA — Here is a free download: authors.elsevier.com/a/1loAH3vVUP... @MolecularCell @Columbia
🤝 #IRBBarcelona Group Leader Cristina Mayor-Ruiz has co-authored a Perspective in #MolecularCell proposing the creation of a #EuropeanAlliance to accelerate the development of proximity-induced therapies.
More information here 🔗 www.irbbarcelona.org/en/news/scie...
🧪 #TargetedProteinDegradation
More information here 🔗 www.irbbarcelona.org/en/news/scie...
🧪 #TargetedProteinDegradation
August 21, 2025 at 3:10 PM
🤝 #IRBBarcelona Group Leader Cristina Mayor-Ruiz has co-authored a Perspective in #MolecularCell proposing the creation of a #EuropeanAlliance to accelerate the development of proximity-induced therapies.
More information here 🔗 www.irbbarcelona.org/en/news/scie...
🧪 #TargetedProteinDegradation
More information here 🔗 www.irbbarcelona.org/en/news/scie...
🧪 #TargetedProteinDegradation
My continued biological education
#LiquidLiquidPhaseSeparation
Phase separation as a new form of regulation in #InnateImmunity
Sensor-Adaptor-Transcription factor-Effector
DNA sensing cGAS-STING-IRF3
RNA sensing PKR
Inflammasome NLRP6
#MolecularCell 2024
www.sciencedirect.com/science/arti...
#LiquidLiquidPhaseSeparation
Phase separation as a new form of regulation in #InnateImmunity
Sensor-Adaptor-Transcription factor-Effector
DNA sensing cGAS-STING-IRF3
RNA sensing PKR
Inflammasome NLRP6
#MolecularCell 2024
www.sciencedirect.com/science/arti...
August 7, 2024 at 11:30 AM
My continued biological education
#LiquidLiquidPhaseSeparation
Phase separation as a new form of regulation in #InnateImmunity
Sensor-Adaptor-Transcription factor-Effector
DNA sensing cGAS-STING-IRF3
RNA sensing PKR
Inflammasome NLRP6
#MolecularCell 2024
www.sciencedirect.com/science/arti...
#LiquidLiquidPhaseSeparation
Phase separation as a new form of regulation in #InnateImmunity
Sensor-Adaptor-Transcription factor-Effector
DNA sensing cGAS-STING-IRF3
RNA sensing PKR
Inflammasome NLRP6
#MolecularCell 2024
www.sciencedirect.com/science/arti...
Proud to introduce our lab’s very first PhD graduate, Dr. Kim (@GyeungYun_Kim)! He defended his thesis today—the same day his first-author paper hit the cover of @MolecularCell. What a way to graduate!
May 16, 2025 at 2:20 AM
Proud to introduce our lab’s very first PhD graduate, Dr. Kim (@GyeungYun_Kim)! He defended his thesis today—the same day his first-author paper hit the cover of @MolecularCell. What a way to graduate!
Very pleased to share our new paper on the translation-coupled resolution of RNA-protein crosslinks @MolecularCell
Our first adventure into the resolution of RNA damage was spearheaded by the brilliant Jackie Cordes and Shubo Zhao
doi.org/10.1016/j.mo...
Our first adventure into the resolution of RNA damage was spearheaded by the brilliant Jackie Cordes and Shubo Zhao
doi.org/10.1016/j.mo...
Redirecting
doi.org
November 10, 2023 at 1:22 PM
Very pleased to share our new paper on the translation-coupled resolution of RNA-protein crosslinks @MolecularCell
Our first adventure into the resolution of RNA damage was spearheaded by the brilliant Jackie Cordes and Shubo Zhao
doi.org/10.1016/j.mo...
Our first adventure into the resolution of RNA damage was spearheaded by the brilliant Jackie Cordes and Shubo Zhao
doi.org/10.1016/j.mo...
The first cancer-related story from our group @WeillCornell
is now published in @MolecularCell. We investigate the role of hyperconnected 3D regulatory hubs in controlling oncogenic programs and properties in glioblastoma and also across 16 cancer types. www.cell.com/molecular-ce...
is now published in @MolecularCell. We investigate the role of hyperconnected 3D regulatory hubs in controlling oncogenic programs and properties in glioblastoma and also across 16 cancer types. www.cell.com/molecular-ce...
Three-dimensional regulatory hubs support oncogenic programs in glioblastoma
Here, Breves et al. profile the 3D enhancer-promoter connectomes of patient-derived
glioblastoma stem cells (GSCs), identify hyperconnected 3D regulatory “hubs” relevant
for GBM biology, examine the i...
www.cell.com
March 27, 2025 at 3:05 AM
The first cancer-related story from our group @WeillCornell
is now published in @MolecularCell. We investigate the role of hyperconnected 3D regulatory hubs in controlling oncogenic programs and properties in glioblastoma and also across 16 cancer types. www.cell.com/molecular-ce...
is now published in @MolecularCell. We investigate the role of hyperconnected 3D regulatory hubs in controlling oncogenic programs and properties in glioblastoma and also across 16 cancer types. www.cell.com/molecular-ce...
How do distal enhancers control transcription dynamics in living cells? Check out our work published in
@MolecularCell!! We show that the dynamic assembly and disassembly of TF clusters at enhancers are a major source of transcriptional bursting. www.cell.com/molecular-ce...
@MolecularCell!! We show that the dynamic assembly and disassembly of TF clusters at enhancers are a major source of transcriptional bursting. www.cell.com/molecular-ce...
Functional coordination between transcription factor clustering and gene activity
The dynamic assembly and disassembly of transcription factor (TF) clusters at enhancers
is a major source of transcriptional bursting in developing Drosophila embryos. Formation
of shared TF clusters ...
www.cell.com
November 11, 2024 at 3:24 AM
How do distal enhancers control transcription dynamics in living cells? Check out our work published in
@MolecularCell!! We show that the dynamic assembly and disassembly of TF clusters at enhancers are a major source of transcriptional bursting. www.cell.com/molecular-ce...
@MolecularCell!! We show that the dynamic assembly and disassembly of TF clusters at enhancers are a major source of transcriptional bursting. www.cell.com/molecular-ce...
Happy to join this platform with some great news 🥳
Some of my recently published PhD work on active #mTOR at #lysosomes made it to the cover of #MolecularCell!
Thanks to @sofiaahola.bsky.social for the wonderful #SciArt🌏🎈🐦🔥
Check out the science behind this art here: www.cell.com/molecular-ce...
Some of my recently published PhD work on active #mTOR at #lysosomes made it to the cover of #MolecularCell!
Thanks to @sofiaahola.bsky.social for the wonderful #SciArt🌏🎈🐦🔥
Check out the science behind this art here: www.cell.com/molecular-ce...
November 22, 2024 at 6:52 PM
Happy to join this platform with some great news 🥳
Some of my recently published PhD work on active #mTOR at #lysosomes made it to the cover of #MolecularCell!
Thanks to @sofiaahola.bsky.social for the wonderful #SciArt🌏🎈🐦🔥
Check out the science behind this art here: www.cell.com/molecular-ce...
Some of my recently published PhD work on active #mTOR at #lysosomes made it to the cover of #MolecularCell!
Thanks to @sofiaahola.bsky.social for the wonderful #SciArt🌏🎈🐦🔥
Check out the science behind this art here: www.cell.com/molecular-ce...
My first review is online @MolecularCell. It was a joy writing this with Brenda Bass and Ryan Andrews in the Bass Lab (I don't think either have migrated to this app), hopefully others will enjoy reading it! Free for 50 days here: authors.elsevier.com/c/1iHXd3vVUP...
December 19, 2023 at 4:27 PM
My first review is online @MolecularCell. It was a joy writing this with Brenda Bass and Ryan Andrews in the Bass Lab (I don't think either have migrated to this app), hopefully others will enjoy reading it! Free for 50 days here: authors.elsevier.com/c/1iHXd3vVUP...