#NKCells
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Nkcells Parasite GIF
ALT: Nkcells Parasite GIF
media.tenor.com
July 13, 2024 at 5:42 AM
March 7, 2025 at 10:37 AM
Congrats Nina, Pietro and @ttilburgs.bsky.social @cincyresearch.bsky.social
Granulysin-high decidual NK cells in macaques and humans share signatures of immune defense
www.cell.com/cell-reports... @cp-cellreports.bsky.social
July 12, 2025 at 3:00 PM
Big thanks to Cancer Discovery and the authors of this commentary for highlighting our work!

Really cool to see our research featured here! ☺️

aacrjournals.org/cancerdiscov...

#CancerResearch #Immunology #NKCells @marinelab.bsky.social
The Dark Side of NK Cells in Cancer Immunotherapy
Summary:. NK cells are a subset of innate lymphoid cells originally identified in mice and humans based on their ability to mediate cytotoxicity against transformed cells. However, two recent back-to-...
aacrjournals.org
September 9, 2025 at 2:01 PM
Interesting new research from Antoine Marçais’ lab showing a central role for pyruvate and the Citrate-Malate Shuttle (non-canonical TCA cycle) in human NK cells.

#immunology #NKcells #Immunometabolism

doi.org/10.1038/s422...

See our commentary article here:

www.nature.com/articles/s42...
Natural killer loops: pyruvate in, lactate out - Nature Metabolism
Resting human CD56Dim natural killer cells utilize exogenous pyruvate to support energy metabolism. A new study shows that these cells take up exogenous pyruvate, which regenerates cytosolic NAD+ via ...
www.nature.com
January 3, 2025 at 12:30 PM
🔬 From 9 Sep: membrane order distinguished NK-cell states with different migration and killing capacity in vitro. A useful state marker, not proof that changing membrane order improves therapy. doi.org/10.1038/s415... #NKCells
Plasma membrane order maps functional diversity in immune cells - Nature Chemical Biology
Cells undergo membrane remodeling in response to the environment to perform specific functions. Now, a cytometry-based method with immune cell biomarker analysis captures variations in plasma membrane...
doi.org
September 20, 2026 at 8:04 AM
NK cells share a universal signature of memory with B and T cells. Come to my presentation at AAI to find out more.

Sunday April 4th 9:30am Room 316C
#AAI2025 #NKcells #ImmuneMemory
April 30, 2025 at 12:23 AM
📣 #EFIS Education Task Force invites you to another webinar in the "Landmark Discoveries in Immunology" series!

💥 Registration is free 👇
🔗 www.efisedu.de/webinar
🗓️ March 5 at 17:00 CET

✨ Share and invite your colleagues!
#immunology #NKCells #ImmunologyEducation

@yefis-immunology.bsky.social
March 2, 2026 at 10:22 AM
About a month ago, I had the honor of giving an invited talk at #NK2025 in beautiful Tasmania. It was a real pleasure to connect with so many bright minds in the field and share some of our latest work on #NKcells and #viruses.
July 7, 2025 at 1:54 PM
From CAR-NK cells to checkpoint inhibitors, Blunt & Khakoo review how boosting NK-cell function could transform cancer therapy.

🔓 Open access: https://bit.ly/4j8dKEW

#Immunotherapy #NKcells #CancerResearch
October 22, 2025 at 3:30 PM
A new KI study published in Nature Immunology shows that CD56bright #NKcells temporarily reside in our organs and then leave them via the lymphatic system. The results change our understanding of how the immune system works in human organs. #Immunology 🧪 news.ki.se/the-immune-s...
October 14, 2025 at 2:38 PM
New review by Cayatte, Picant, Vétizou, & @ericvivier.bsky.social @ciml.bsky.social explores the expanding roles of #NKcells beyond #cancer, highlighting their pivotal functions in viral #infections, #neurodegeneration, #autoimmune diseases, and #transplantation medicine rupress.org/jem/article/...
December 17, 2025 at 6:15 PM
🧬 Which solid tumours should NK cell therapies target? Tissue analysis, a review of 177 trials and >10,000 TCGA samples offer a framework for prioritisation @ericvivier.bsky.social

pmc.ncbi.nlm.nih.gov/articles/PMC...
#NKcells #Immunotherapy
A Multimodal Framework to Guide Solid Tumor Indications for Natural Killer Cell‐Based Therapy
T cell‐based immunotherapies have achieved remarkable success in hematological malignancies but remain limited in solid tumors. Natural killer (NK) cells offer a compelling complementary approach, giv...
pmc.ncbi.nlm.nih.gov
September 21, 2026 at 6:44 AM
I am thrilled to share that my PhD research project has just been published in @natureportfolio.bsky.social #NatureAging !
We discovered how senescent cells use the ganglioside GD3 as a Senescence Immune Checkpoint to escape immune clearance. #NKcells #Siglec7
www.nature.com/articles/s43...
A ganglioside-based immune checkpoint enables senescent cells to evade immunosurveillance during aging - Nature Aging
This study identifies a novel immune checkpoint in senescent cells that is linked to the ganglioside GD3 and that contributes to the evasion of immune clearance by these cells and to aging and age-rel...
www.nature.com
December 31, 2024 at 3:18 PM
Lots of interest in how to maintain healthy mitochondria for effective cell therapy, like #NKcells for cancer immunotherapy. Some interesting clues in this article.
#immunosky #immunometabolism

Triacylglycerol mobilization underpins mitochondrial stress recovery
www.nature.com/articles/s41...
Triacylglycerol mobilization underpins mitochondrial stress recovery - Nature Cell Biology
Baker et al. show that mitochondrial stress recovery requires mobilization of lipid droplet triacylglycerol stores to facilitate cardiolipin biosynthesis and mitochondrial biogenesis.
www.nature.com
January 15, 2025 at 1:30 AM
🆕 Our back-to-back papers reveal a surprising villain in ICB resistance: NK cells.

🧬 Targeting regulatory NK cells may boost T cell–driven immunotherapy.

#Immunotherapy #CancerResearch #ICB #NKcells #Melanoma #CD8Tcells
Cytotoxic NK Cells Impede Response to Checkpoint Immunotherapy in Melanoma with an Immune-Excluded Phenotype
AbstractImmune checkpoint blockade (ICB) has revolutionized cancer treatment. Unfortunately, the inability of lymphocytes to infiltrate the tumor nest, a phenomenon known as immune exclusion, drastica...
aacrjournals.org
June 18, 2025 at 1:36 PM
⚡ Stayed active longer than usual
💥 Avoided dangerous immune storms that sometimes affect #CAR-T therapies
A huge leap toward safer, longer-lasting cancer #immunotherapies! 🙌
#CancerResearch #Biotech #MIT #Harvard #NKCells #FutureOfMedicine
Engineered “natural killer” cells could help fight cancer
Researchers found a way to engineer CAR-NK immune cells that makes them much less likely to be rejected by the patient’s immune system, a common drawback of this type of cancer immunotherapy.
news.mit.edu
October 24, 2025 at 3:41 PM
Large-scale investigation confirms TRPM3 ion channel dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

Sonya Marshall-Gradisnik et al. 🇦🇺

#ME/CFS #TRPM3 #IonChannel #NKcells
Frontiers | Large-scale investigation confirms TRPM3 ion channel dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
IntroductionMyalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a chronic disease hallmarked by multiple systemic symptoms, such as neurocognitive...
www.frontiersin.org
March 25, 2026 at 3:33 PM
I officially deleted X! Follow me here for sporadic but semi-useful content about research ( #ovariancancer #bioinformatics #immunology #nkcells #singlecell #spatialbiology), my business (www.designsthatcell.ca #scicomm #sciart), and my very non-chaotic life as a mom of 2 under 4.
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January 27, 2025 at 7:28 PM
Thanks @labwaggoner.bsky.social! All datasets publicly available on GEO. While we focus on #ILC2, #ILC3s and #NKcells, we capture all immune cells in human spleen. So hoping the datasets can be a good resources for the community!
August 12, 2026 at 3:19 AM
How Natural Killer cell lysate reduces the damage caused by Lymphodepletion in T-cell therapies
#immunosky #medsky #NKcells #Cancer #Cytokines

cloud.hoststar.ch/s/aecHWe5LXS...
November 9, 2025 at 8:41 PM
Hyunu Kim et al. @josephsunlab.bsky.social show that, in activated #NKcells, IL-12 remodels the RNA polymerase II landscape within minutes, increasing IFN-γ promoter occupancy and pausing in a STAT4- and DDX5-dependent manner. rupress.org/jem/article/...
June 18, 2026 at 4:00 PM
#bluetoirial courtesy of @mskcancercenter.bsky.social Roni Shouval Now out in #BloodCancerDiscovery Comprehensive study (n=263) on immune reconstitution after CD19 #CARTcells (axi/liso/tisa-cel) in LBCL. Led by the talented
@DannyLuan6 #Lymphoma #NKcells #lymsm 1/6
aacrjournals.org/bloodcancerd...
Dynamics of Immune Reconstitution and Impact on Outcomes Across CAR-T Cell Products in Large B-Cell Lymphoma
Abstract. Patients treated with chimeric antigen receptor T-cell (CAR-T) therapy are subject to profound immune suppression. Dynamics of immune reconstitution (IR) and impacts of IR on outcomes follow...
aacrjournals.org
December 14, 2024 at 2:31 PM
Excited to share our News & Views with @tsailab.bsky.social, highlighting a new study by Krapić et al. linking #NKcells to metabolic changes in visceral adipose tissue that shape anti-viral adaptive immunity. Read more here: www.nature.com/articles/s42... #Immunosky #Immunology #Metabolism
The art of war: burning stores to fuel anti-viral immunity - Nature Metabolism
Adipose tissues are increasingly recognized as dynamic hubs where immune cell–adipocyte cross-talk coordinates processes such as energy metabolism, inflammation and thermogenesis. In this issue, Krapi...
www.nature.com
April 11, 2025 at 3:07 PM
In our new preprint, we investigate NK cell dysfunction and immunometabolic alterations in SLE, exploring how HCQ influences mitochondrial recycling 🧬🔬

🔗 Read here: www.medrxiv.org/content/10.1...

Feedback welcome!

#Lupus #Autoimmunity #Immunology #NKCells #Immunometabolism #HCQ #Mitochondria
Hydroxychloroquine corrects mitochondrial recycling dysfunction in natural killer cells from patients with systemic lupus erythematosus
Objectives Natural Killer (NK) cell dysfunction contributes to systemic lupus erythematosus (SLE) pathogenesis, but the underlying mechanisms remain poorly understood. This study investigates immunome...
www.medrxiv.org
February 10, 2025 at 9:50 AM