#amyloidbeta
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pnas.org
#Alzheimers disease linked to viral #immune response in #brain. In PNAS Journal Club: www.pnas.org/post/journal...

#dementia #HerpesVirus #AmyloidBeta #tau #neurodegeneration #HSV1
The phosphorylation (yellow) of tau proteins (red-orange) by kinases (violet) causes microtubules in the neuron axon to break down, thus interrupting the transport of synaptic vesicles (orange-blue). But tau also seems to have a protective effect against herpes simplex virus infection. Image credit: Shutterstock/Juan Gaertner.
January 24, 2025 at 6:57 PM
gmj-georgia.bsky.social
TGen researchers at City of Hope have uncovered a protein cascade mechanism where amyloid-beta plaques trigger tau and alpha-synuclein accumulatio…

#Alphasynuclein #Alzheimers #Amyloidbeta #Mixedpathology #Neurodegeneration

#Alphasynuclein #Alzheimers #Amyloidbeta #Mixedpathology #Neurodegenera…
How Amyloid Plaques Trigger Multiple Protein Pathologies
TGen researchers at City of Hope have uncovered a protein cascade mechanism where amyloid-beta plaques trigger tau and alpha-synuclein accumulatio… #Alphasynuclein #Alzheimers #Amyloidbeta #Mixedpathology #Neurodegeneration
news.gmj.ge
September 30, 2026 at 11:26 AM
claudiogomeslab.bsky.social
Our reseach combines #biochemistry, biophysics, and cell biology to unravel #ProteinInteractions and self-assembly and how #chaperones influence aggregation, #PhaseSeparation and #proteostasis. The image depicts S100B, a chaperone acting on #Tau and #AmyloidBeta, and one of our favorite models 🧪
March 13, 2025 at 8:04 PM
mfnavedo.bsky.social
Just in time for the Holidays, our latest paper on how #amyloidbeta regulates the spatiotemporal properties of vascular L-type channels - implications for vascular function.

Great work by Jade and team! @ucdavis.bsky.social, @ucdavishealth.bsky.social

physoc.onlinelibrary.wiley.com/doi/10.1113/...
Amyloid β alters vascular CaV1.2 channel spatiotemporal properties
Abstract figure legend Amyloid-β1-42 (Aβ1-42) triggers a male-specific signalling cascade influencing CaV1.2 spatiotemporal properties in cerebral vascular smooth muscle. The signalling pathway invol...
physoc.onlinelibrary.wiley.com
December 20, 2025 at 1:17 PM
apcmicrobiomeirel.bsky.social
@anatneuroucc.bsky.social @uccresearch.bsky.social
#Neuroscience #AmyloidBeta #BrainResearch
Congratulations on also making the cover of the May 2026 issue of Neuroscience Bulletin
May 14, 2026 at 6:57 AM
kbi-uhn.bsky.social

📰✨Congratulations to Dr. Donald Weaver, Senior Scientist at UHN’s Krembil Brain Institute, for his recent feature in the online publication, Undark magazine!

🔗: in bio!

#Alzheimers #Dementia #AmyloidBeta

@uhntoronto.bsky.social
@uhnfoundation.bsky.social
@uhnresearch.bsky.social
@bradwouters.com
January 13, 2025 at 4:09 PM
sjorsscheres.bsky.social
Yang's work on #amyloidbeta filaments from meninges is now out. A reminder that it is better not to build atomic models de novo into #cryoEM reconstructions of #amyloids at resolutions lower than 4A.
rdcu.be/dsLP5
December 5, 2023 at 9:50 AM
newsmedical.bsky.social
Semaglutide enhances cognitive abilities and reduces Alzheimer’s pathology in mice and human brain models 🔬🧠🧪 www.news-medical.net/news/2024101... #Alzheimers #Neuroprotection #Semaglutide #Oxytocin #Brain #Neuroscience #AmyloidBeta #TauProtein
Semaglutide enhances cognitive abilities and reduces Alzheimer’s pathology in mice and human brain models
Researchers find that Semaglutide improves cognitive function and reduces amyloid and tau pathology in Alzheimer's disease models, while restoring oxytocin levels in both mice and human brain organoid...
www.news-medical.net
October 15, 2024 at 2:04 AM
sankoreschriften.bsky.social
Although neurons are the main producers of amyloid beta, oligodendrocytes also produce a significant amount of the protein which is incorporated into plaques. #neuroscience #Alzheimer #amyloidbeta #oligodendrocytes
Alzheimer’s disease: It’s not only neurons
New research findings on Alzheimer's: It is not only nerve cells that produce harmful beta-amyloid proteins. Glial cells also contribute to this.
www.mpinat.mpg.de
August 16, 2024 at 5:15 AM
newsmedical.bsky.social
Oligodendrocytes identified as key amyloid β producers in Alzheimer's disease 🔬🧠🧬 www.news-medical.net/news/2024072... #Alzheimers #NeuroScience #Oligodendrocytes #AmyloidBeta #BrainHealth #Pathology #Neurodegeneration #Therapeutics #Medical @plos.bsky.social
Oligodendrocytes identified as key amyloid β producers in Alzheimer's disease
Researchers discovered that oligodendrocytes, not just neurons, produce amyloid β in Alzheimer's disease, and suppressing their activity improves disease pathology. This finding suggests new therapeut...
www.news-medical.net
July 25, 2024 at 2:57 AM
teanijarv.bsky.social
I am very excited to let you know that my first PhD study has now been published in Nature Communications. 🧠📄 See the link to the article or read a summary in the post below! ⬇️

#alzheimersdisease #tau #amyloidbeta #neuroimaging #MRI #PET
September 5, 2025 at 2:58 PM
stressmarq.bsky.social
StressMarq will be exhibiting at #ADPD2026 from March 17-21 in Copenhagen!📍

Visit us at Booth No. 70 to learn more about our unique products for #Alzheimers & #Parkinsons disease research. 🧠

Learn more 🍁 https://bit.ly/2II2Jeg
##AlphaSynuclein #Tau #AmyloidBeta #TDP43 #TTR #SOD1
March 18, 2026 at 6:55 PM
stressmarq.bsky.social
StressMarq will be exhibiting at #ADPD2026 from March 17-21 in Copenhagen!📍

Visit us at Booth No. 70 to learn more about our unique products for #Alzheimers & #Parkinsons disease research. 🧠

Learn more 🍁 https://bit.ly/2II2Jeg
##AlphaSynuclein #Tau #AmyloidBeta #TDP43 #TTR #SOD1
March 11, 2026 at 6:55 PM
neurodegeneration.bsky.social
[BioRxiv] The circadian clock regulates scavenging of fluid-borne substrates by brain border-associated macrophages

https://doi.org/10.64898/2025.12.08.693074

#neurodegeneration #biorxiv #amyloid #amyloidbeta #Alzheimers
BioRxiv Article
doi.org
December 12, 2025 at 12:27 AM
newsmedical.bsky.social
Amyloid-β and tau disrupt brain activity, driving early cognitive decline in Alzheimer’s risk 🧠🔬🧓 www.news-medical.net/news/2024092... #Alzheimers #Neuroscience #Brain #CognitiveDecline #AmyloidBeta #TauProtein #Dementia #Neurophysiology #PreventAD #Aging
Amyloid-β and tau disrupt brain activity, driving early cognitive decline in Alzheimer’s risk
Researchers discover how amyloid-β and tau pathologies interact to drive early neurophysiological changes and cognitive decline in older adults at risk of Alzheimer’s disease.
www.news-medical.net
September 20, 2024 at 5:03 AM
newsmedical.bsky.social
PET imaging and proteomics reveal distinct protein signatures in Alzheimer's disease progression 🧠🔬🧪 www.news-medical.net/news/2024082... #Alzheimers #Neurodegeneration #PETImaging #Proteomics #AmyloidBeta #TauPathology #CognitiveDecline #Brain #Neuroscience
PET imaging and proteomics reveal distinct protein signatures in Alzheimer's disease progression
Researchers used PET imaging and proteomic analysis of cerebrospinal fluid to study amyloid β and tau tangle loads in Alzheimer's patients, identifying 127 proteins linked to disease progression. The ...
www.news-medical.net
August 28, 2024 at 5:14 AM
srv-tifrh.bsky.social
Amyloid-β undergoes phase separation on lipid membranes, forming condensates that promote primary nucleation. This early aggregation step can be targeted for therapeutic intervention in Alzheimer’s.
#Alzheimers #AmyloidBeta #LLPS #Neurodegeneration #Biophysics
@pnas.org
Lipid-induced condensate formation from the Alzheimer’s Aβ peptide triggers amyloid aggregation | PNAS
The onset and development of Alzheimer’s disease is linked to the accumulation of pathological aggregates formed from the normally monomeric amyloi...
www.pnas.org
April 18, 2025 at 10:36 AM
hmariclab.bsky.social
Just reviewed @elife.bsky.social
Epitope Sequence and Modification Fingerprints of Anti-Aβ Antibodies

Resource & deep dive into how therapeutic & research #Antibody detect key #AmyloidBeta variants in #AlzheimersDisease

Thanks @unimedizin-goe.bsky.social, @mpi-nat.bsky.social & @uni-wuerzburg.de !
ivantalucci.bsky.social Ivan Talucci @ivantalucci.bsky.social · May 10
Happy to share the positive review for "Epitope Sequence and Modification Fingerprints of Anti-Aβ Antibodies" doi.org/10.7554/eLif...
Now online in @elife.bsky.social
Looking forward to sharing the revised version!🔜
@hmariclab.bsky.social @uni-wuerzburg.de @maxplanck.de @unimedizin-goe.bsky.social
Epitope Sequence and Modification Fingerprints of Anti-Aβ Antibodies
doi.org
May 12, 2025 at 2:01 PM
rpeptide.bsky.social
This @alzdemjournals.bsky.social study identifies the Tau isoform 1N4R as a key driver of neuronal vulnerability to #AmyloidBeta and phosphorylated #Tau in MAPT knockout human iPSC-derived neurons. rPeptide’s Aβ40 and Aβ42 was used to model AD-related toxicity.

Paper: t.ly/XFF_6
BA: t.ly/QLggQ
The tau isoform 1N4R confers vulnerability of MAPT knockout human iPSC‐derived neurons to amyloid beta and phosphorylated tau‐induced neuronal dysfunction
INTRODUCTION Human tau protein, composed of six brain-specific isoforms, is a major driver of Alzheimer's disease (AD). The role of its isoforms however remains unclear and human AD models are scarc...
t.ly
May 12, 2025 at 3:48 PM
achronicvoice.com
“Researchers at UC San Francisco identified a molecular #receptor that enables #microglia to gobble up and digest #AmyloidBeta plaques. Without the receptor, ADGRG1, the microglia barely nibbled on the toxic protein.”: buff.ly/Yj4Uqvs

via sciencedaily
#AlzheimersDisease #ClinicalResearch
Scientists discover the receptor that helps your brain clean itself—and fight Alzheimer’s
Scientists at UCSF have uncovered how certain immune cells in the brain, called microglia, can effectively digest toxic amyloid beta plaques that cause Alzheimer’s. They identified a key receptor, ADGRG1,...
buff.ly
July 29, 2025 at 4:30 PM
stressmarq.bsky.social
Product Citation: #Synaptic dysfunction is an early result of #Alzheimer's disease. StressMarq's ENaC alpha Antibody was used to demonstrate the role of ENaC in modulating oligomeric #AmyloidBeta activity.

Paper 📕 bit.ly/4k4qUTK
Product 🧠 bit.ly/4cZUBTI
May 13, 2025 at 4:34 PM
newsmedical.bsky.social
Cholesterol imbalance linked to neurodegeneration, study suggests potential strategies for intervention 🧠🧬🔬 www.news-medical.net/news/2024080... #Neurodegeneration #Cholesterol #Alzheimers #Parkinsons #Huntingtons #Brain #Research #Therapeutics #AmyloidBeta
Cholesterol imbalance linked to neurodegeneration, study suggests potential strategies for intervention
Research highlights how cholesterol imbalances in the brain contribute to neurodegenerative diseases like Alzheimer's, Huntington's, and Parkinson's, suggesting targeted therapeutic interventions.
www.news-medical.net
August 5, 2024 at 4:25 AM
stressmarq.bsky.social
Product Citation 🌟

Trichostatin A (TSA), commonly used in cancer studies, may also be #neuroprotective. In a neuronal model, TSA significantly improved cell viability in the presence of StressMarq's #AmyloidBeta 1-42 Oligomers.

Paper 🧩 https://bit.ly/4scYknu
Product 📚 https://bit.ly/4gYWkcj
March 15, 2026 at 7:46 PM
stressmarq.bsky.social
We're exhibiting at #WPC2026 from May 25-27 in Phoenix, AZ! ☀️

Visit us at Booth 421 to learn how our innovative products — including PFFs, Oligomers, Monomers, Antibodies & more — are advancing #PD research worldwide. 🧠

🍁 Learn more: https://bit.ly/2zo1saf
##AlphaSynuclein #Tau #AmyloidBeta
May 20, 2026 at 9:11 PM
stressmarq.bsky.social
💫 Enhancing Sox9 in #astrocytes upregulates the MEGF10-mediated clearance of #AmyloidBeta plaques, safeguarding cognitive function in #neurodegenerative disease models.

Review the key findings from this study on the StressMarq blog ⭐ https://bit.ly/4qZ2Eq7
Enhancing the Astrocytic Clearance of Amyloid Beta
Astrocytic Sox9 promotes amyloid beta clearance and preserves cognition, revealing new astrocyte-driven therapeutic strategies for Alzheimer’s disease.
bit.ly
February 5, 2026 at 5:46 PM