#3Dgenome
October GOA speaker is Vijay Ramani @vram142.bsky.social from @gladstoneinst.bsky.social: Single-molecule methods to understand multi-scale chromatin structure.
Registration link: unimelb.zoom.us/webinar/regi...

27th October:
Melbourne 10 am AEST
San Francisco 4 pm PDT
#3Dgenome
#CTCF
#Chromatin
October 13, 2026 at 1:20 AM
Our September GOA speaker is Aleksandra Pękowska aleksandrapekowska.bsky.social. Join us to hear her talk titled: RNA-dependent regulation of CTCF-anchored chromatin topology during differentiation.
Registration link: unimelb.zoom.us/webinar/regi...

#3Dgenome
#CTCF
#Chromatin
September 15, 2026 at 12:02 AM
BATUT LAB | Columbia
www.batutlab.com
September 10, 2026 at 6:55 PM
Excited to present my poster, “A 3D Genome Framework for Causal Variant Fine-Mapping and Tissue-Specific Gene Regulation,” at @geneticssociety.bsky.social #ASHG2025 in Boston!

📌 Epigenetics Poster (Poster #8041F)
📅 Fri, Oct 17 | 2:30–4:30 PM EDT

#Genomics #Genetics #Epigenetics #3DGenome
October 8, 2025 at 12:38 AM
Michal Gdula group leader at @uam-ibmib.bsky.social is saerching for a postdoc to work on the epigenetics of pancreatic cancer within colaborative OPUS-LAP funded by @ncn.gov.pl and @dfg.de - reach out! #3Dgenome #cancer #pancreas
We’re recruiting! Three-year, fully funded #postdoc opportunity: pancreatic cancer #epigenetics & potential new treatments (funded by @ncn.gov.pl & @dfg.de ). Collaboration with @akispapantonis.bsky.social, University of Göttingen (OPUS-LAP). See the ad & contact me! drive.google.com/file/d/1vrFd...
February 5, 2026 at 4:01 PM
Our project will be conducted by teams from @ugent-fge.bsky.social and @uzgent.be @elfridedebaere.bsky.social Burcu Cicekdal @krisvleminckx.bsky.social Thomas Naert & Institut Imagine Jean-Michel ROZET Lucas Fares-Taie

#3Dgenome
#enhanceropathy
#Xenopus
#SOX21
#glaucoma
June 24, 2025 at 11:34 PM
As 'DC5' of @progret2024.bsky.social you leverage long-read sequencing approaches to gain more insight into 3D genomes of human retina, RPE, iPSC-ROs and iPSC-RPE. This will advance our understanding of difficult-to-interpret non-coding variants and SVs in retinal diseases.
#LRS #3Dgenome ##SV #IRD
The true game-changer of 2024? In September, I embarked on my biggest adventure yet: moving to Ghent,Belgium🇧🇪to start my PhD in @elfridedebaere.bsky.social’s lab under the @progret2024.bsky.social fellowship.Big thanks to the lab for a warm welcome.I’m already building some unforgettable memories.👨‍🔬✨
January 30, 2025 at 8:11 PM
New Preprint from Puri lab and first co-corresponding manuscript for me!
Big thanks to all the collaborators.

#transcription #myoskeet #myogenesis #3Dgenome #superenhancers

a skeetorial will come soon :) now it is time to celebrate!!! 🥳

www.biorxiv.org/content/10.1...
E-box independent chromatin recruitment turns MYOD into a transcriptional repressor
MYOD is an E-box sequence-specific basic Helix-Loop-Helix (bHLH) transcriptional activator that, when expressed in non-muscle cells, induces nuclear reprogramming toward skeletal myogenesis by promoti...
www.biorxiv.org
December 6, 2024 at 2:53 AM
Hi all!
We developed CAD-C to map chromatin organization at high res in yeast. It revealed an unexpected tight alignment: nucleosomes covering the same sequence tend to be associated across sister chromatids.

www.biorxiv.org/content/10.6...

#3DGenome #chromatin #Cohesin #centromere
CAD-C reveals centromere pairing and near-perfect alignment of sister chromatids
Three-dimensional (3D) genome organization plays a central role in gene regulation, chromatin folding, and genome stability. Although chromosome-conformation capture (3C)-derived methods have revoluti...
www.biorxiv.org
December 20, 2025 at 4:43 PM
Hello everybody,
I am looking for an Engineer (IE) to help me start the lab at LBMC / ENS-Lyon in April.
We will investigate chromatin organization during replication in yeast.
RT appreciated!
To apply: inserm.softy.pro/offre/187863

@lbmcinlyon.bsky.social
#NewPI #3DGenome #chromatin #replication
December 18, 2025 at 5:52 PM
Hi all !
Happy to share that I will open a lab at the LBMC at ENS-Lyon thanks to the #ATIP-Avenir funding.
We will investigate the role the 3D chromatin organization in Replication and Repair.

www.ens-lyon.fr/LBMC/equipes...


Job offers out soon!
#NewPI #3DGenome #chromatin #replication
Chromatin Architecture in Replication and Repair (CARR) — Laboratoire de Biologie et Modélisation de la Cellule
Personal tools
www.ens-lyon.fr
December 17, 2025 at 8:13 AM
🧬 This review delves into the advancements in 3D genome architecture mapping, revealing how spatial genome organization influences gene expression, cellular function, and disease mechanisms.

🔗 DOI: doi.org/10.1016/j.cs...

📚 CSBJ: www.csbj.org

#Genomics #3DGenome #HiC #Epigenomics #DNA
March 22, 2025 at 11:08 AM
Looking forward to Mike's @drmrobson.bsky.social talk & visit - join us in Poznan Morasko Campus tomorrow @ 10:30! #Lamins #3Dgenome #epigenetics
Join us next Friday on 25th April for the @uam-ibmib.bsky.social seminar: Mike Robson @drmrobson.bsky.social from Max Delbrück Center @mdc-berlin.bsky.social will tell us abut the genome-lamina interactions during limb development! thanks to ID-UB POB2 for funding! #epigenetics #LADs #chromatin
April 24, 2025 at 10:59 AM
2️⃣ 𝘛𝘩𝘦 𝘧𝘪𝘳𝘴𝘵 𝘴𝘵𝘦𝘱
To provide new answers to these questions, researchers began by obtaining the tiny gonadal cell populations before and after sex determination. Surprisingly, even using Hi-C and ChIP-seq, only minimal 3D chromatin changes were observed

#3DGenome #Nature #Research #HiC #ChIPSeq
February 24, 2026 at 10:21 AM
December 14, 2024 at 9:39 AM
⏪ G&D RECAP ⏪

🗓️ March 2025
RESEARCH PAPER: Two unrelated distal genes activated by a shared enhancer benefit from localizing inside the same small topological domain
By Huang et al. and Wouter de Laat
➡️ https://genesdev.cshlp.org/content/39/5-6/348.full

#enhancer #3Dgenome #CTCF #TADs #chromatin
December 16, 2025 at 7:01 PM
RESEARCH PAPER: Bystander activation across a TAD boundary supports a cohesin-dependent transcription cluster model for enhancer function
By Williamson et al.
➡️ https://tinyurl.com/gd352648

#chromatin #enhancer #transcription #sonichedgehog #TAD #cohesin #genomics #3Dgenome #loopextrusion
September 15, 2025 at 3:04 PM
📽️ G&D Tapes 📽️

G&D Author, Marion Solbach Mouginot tells us about their recent study in #genesdev describing how meta-domains control neuronal gene expression.

Learn more here:
➡️ bit.ly/45wGi5M

#TAD #chromatin #transcription #neuron #drosophila #3Dgenome
August 14, 2025 at 7:13 PM
New study reveals 3D genome reorganization in Actinidia arguta, identifies AaCBP60B-like as key gene for anthocyanin regulation. #3DGenome #Anthocyanin #GeneDiscovery @oxfordacademic.bsky.social
Details: doi.org/10.1093/hr/u...
October 28, 2025 at 3:10 PM
AI Is Decoding the 3D Genome 🧬
MIT scientists have developed an AI model that can predict the 3D structure of the genome in minutes - far faster than existing experimental methods

learn more: www.synbiobeta.com/read/ai-is-d...

#AI #Genomics #3DGenome #MITResearch #ArtificialIntelligence #Biotech
AI Is Decoding the 3D Genome—And It’s Doing It Faster Than Humans Ever Could - SynBioBeta
www.synbiobeta.com
February 13, 2025 at 10:56 PM
TECHNOLOGY: Job Dekker from @umasschan.bsky.social  and Howard Hughes Medical Institute explored the mitotic inheritance of chromosome folding programs at the 2026 AGBT General Meeting.

#AGBTGM26 #Genomics #3DGenome
February 26, 2026 at 8:52 PM
Excited to share I’ve received a #SSMF #Consolidator grant!

📣 Recruiting a #postdoc to study #cancer #neuroscience #3Dgenomics #multiomics #singlecellomics

🔬How neural inputs shape #3Dgenome and #cellplasticity in #glioblastoma #GBM

Interested? Apply now 👇
rb.gy/m7xz7b
Postdoctoral Researcher in "Cancer Neuroscience: the impact of neural activity on 3D genome organization and cellular plasticity in glioblastoma”
rb.gy
November 14, 2025 at 11:00 AM
Over a year ago in @natcomms.nature.com we showed how rewiring of #enhancer landscape & #3Dgenome underlies #neuron-to-glioma synaptic communication in #GB. SMAD3 & PITX1 emerged as key #TF and targeting them alters tumour growth.
doi.org/10.1038/s414...
Rewiring of the promoter-enhancer interactome and regulatory landscape in glioblastoma orchestrates gene expression underlying neurogliomal synaptic communication - Nature Communications
The integration of transcriptomics and epigenomics data helps to better understand the regulatory and topological changes in glioblastoma subtypes. Here, the authors map the promoter-enhancer interact...
doi.org
May 21, 2025 at 8:55 AM
7/n Here, we applied METALoci, an approach that integrates #3DGenome and #Epigenetics data into a unified framework maps, developed by @jrotwitguez.bsky.social & @mamartirenom.bsky.social from @cnag-eu.bsky.social @crg.eu
February 24, 2026 at 2:03 PM
🤩💪 Out now! 3D regulatory hubs in sex determination

With @mamartirenom.bsky.social & Capel labs, led by @imotagom.bsky.social & @jrotwitguez.bsky.social

1️⃣ METALoci – explore #3DGenome 🧬
2️⃣ Non-coding region controlling Fgf9 🧩
3️⃣ Meis genes = new key players 🌟

👉 rdcu.be/e5sm2

1/n Bluetorial 👇
Chromatin spatial analysis by METALoci unveils sex-determining 3D regulatory hubs
Nature Structural & Molecular Biology - METALoci, a new three-dimensional genome computational tool, reveals a major rewiring of regulatory interactions during sex determination. By combining...
rdcu.be
February 24, 2026 at 2:03 PM