#Mastcell
My occasional reminder of *Coded = Counted*

U09.9: Post-Covid conditions, unspecified
G90.9: Disorder of the autonomic nervous system, unspecified
G90.A: #POTS
G93.32: #ME/CFS
Q79.60: #EhlersDanlos syndrome, unspecified
M35.7: hypermobility syndrome
D89.40: #Mastcell activation, unspecified
October 20, 2026 at 5:23 PM
Alejandro Schcolnik-Cabrera @ualberta.bsky.social and Rommel Chacón-Salinas #IPNENCB present a News & Views highlighting a recent @jem.org article reporting a #Nerve-#MastCell-#Macrophage circuit associated with tissue repair following sterile injury
The light side of mast cell degranulation: delivering macrophage repair through molecular condensates
Salm et al. identified a nerve-mast cell-macrophage circuit in which cytoneme-delivered mast cell condensates promote macrophage aggregation and tissue rep
doi.org
October 12, 2026 at 7:17 PM
September 9, 2026 at 2:32 PM
www.science.org/doi/10.1126/...

Activation of glutamate receptor GluK2 with a topical
#smallmolecule inhibits dermal #mastcell degranulation in #eczema
Possible applications for this mechanism in #allergy ?
#immunosky
#medsky
🧪
Agonism of the glutamate receptor GluK2 suppresses dermal mast cell activation and cutaneous inflammation
Small-molecule agonism of GluK2 reduces dermal mast cell responses to MrgprB2 ligation and suppresses skin inflammation.
www.science.org
January 7, 2025 at 9:01 AM
Next Sunday’s Mastie meeting will have the official announcement—but I’d love to have a few early adopters on board. 💪 Let’s create the community we’ve been waiting for. Link in bio! 🌿 4/4 #mcas #dysautonomia #longcovid #mastcell #histamine
January 20, 2025 at 6:07 PM
Proud to share our latest paper in Science Immunology
- how #mastcell -derived #BH4/#serotonin drives postoperative pain in mice, revealing a potential therapeutic target for surgical pain:

scim.ag/87H
Mast cell–derived BH4 and serotonin are critical mediators of postoperative pain
Mast cells and their BH4-serotonin metabolic axis are critical drivers of postoperative pain hypersensitivity in mice.
scim.ag
August 23, 2024 at 7:23 PM
This study’s explanation for the hyperinflammatory responses in #covid & the chronic inflammation in #longCOVID . #Mastcell degranulation contributes to tissue injury in 🫁 🧠 & airway epithelium that may be the underlie LC symptoms such as fatigue, brain fog, dysautonomia….
May 21, 2025 at 2:11 PM
mastcell360.com/top-signs-yo...

Hey gang. Merry Christmas Eve Eve Eve Eve. I’ve been dealing with this issue for over 15 years and this article succinctly sums up the root causes. I hope this helps someone on their very expensive journey for answers. 🙏
#mastcell #MECFS #moody #tiredofbeingsick
Mold Toxicity Symptoms with MCAS – Mast Cell 360
For decades, I struggled with numerous, terrible symptoms. But my bloodwork was always completely normal. Could Mold Toxicity be causing your MCAS?
mastcell360.com
December 22, 2024 at 4:03 PM
NEW BLOG POST - where I've been the last 10 days. Health concerns, layered with #CSA induced self-doubt and fear of not being believed. Sound familiar? Sigh. #childsexualabuse #survivor #trauma #mastcell #chronicillness #memoir <a href="http://patriciadebney.com/2022/04/28/something-is-wrong/" class="hover:underline text-blue-600 dark:text-sky-400 no-card-link" target="_blank" rel="noopener" data-link="bsky">http://patriciadebney.com/2022/04/28/something-is-wrong/
something is wrong
[image: mast cells, stained] I am aware that more days th...
patriciadebney.com
November 16, 2024 at 5:38 PM
The Chain Reaction Leading to Systemic Inflammation - Prof David Putrino MD breaks down what's happening.

#longcovid #longcovidtheanswers #longhauler #mecfs #mastcell #spikeprotein #inflammation

www.youtube.com/shorts/whHw_...
The Chain Reaction Leading to Systemic Inflammation - Prof David Putrino MD breaks down what's happe
YouTube video by Long Covid The Answers
www.youtube.com
October 15, 2025 at 7:43 PM
The Chain Reaction Leading to Systemic Inflammation - Prof David Putrino MD breaks down what's happening.

#longcovid #longcovidtheanswers #longhauler #mecfs #mastcell #spikeprotein #inflammation
October 15, 2025 at 5:29 PM
Learn about MCAS, Mast Cell Activation Syndrome, in our new podcast out tomorrow at 5pm PT.
Featuring Dr David Lyons Kaufmann.

Longcovidtheanswers.com
#mastcell #mcas #mastcellactivation #longhauler #longcovid
December 19, 2024 at 5:18 PM
Trying a new mastcell-stabilizer and I hope things will improve again because the last days were just a hell of symptoms and I feel absolutely drained.

Sick and tired of being sick and tired.
September 6, 2024 at 2:21 PM
Unraveling Mast Cell Activation Syndrome. Many of us are seeing increasing numbers of patients asking if they might have a mast cell disorder. Join Onyinye Iweala, MD, PhD, FAAAAI, as we discuss MCAS and how to better understand this confusing disorder. #MCAS #MastCell
www.aaaai.org/professional...
August 19, 2025 at 4:46 PM
Today our favorite #mastcell infection-ologist Chris von Beek nailed his #PhD thesis to the group log. Looking forward to an exciting defense. They grow up so fast...
April 29, 2025 at 2:36 PM
I have taken an extra Allegra, my cromolyn nose spray, and I just took a Benadryl. My normal MCAS meds are: Allegra 180 mg, Xyzal 10 mg, oral cromolyn sodium before every time I eat. Anyone have any "get out of a mast cell flare" recommendations for me?
#MCAS #NEISVoid #mastcell #mastcellactivation
May 12, 2025 at 11:50 AM
January 21, 2025 at 11:24 PM
Then, there’s the ever present #mastcell reactions, that can happen with anything, at any time. For all these reasons, it is important to take a systematic approach to introducing supplements. This requires research and time 4/13
November 30, 2023 at 12:05 AM
that's good to hear as both me and son get mastcell-sick for some weeks after the mRNA shot.

but for this year we will have to put up with it again.

on the bright side, my GP is now a firm believer that angry mastcells are the rootcause of my illness.

magical, a doctor that gets why you're sick
October 28, 2023 at 12:15 AM
Calling all #MastCell, #Basophil and #Eosinophil afficionados!
Registration and abstract submission for the 12th Int. Conference of the European Mast Cell and Basophil Research Network (EMBRN) in Vienna, Austria, from June 10th-12th, 2026, is open at innere-med-1.meduniwien.ac.at/EMBRNconfere...
March 19, 2026 at 8:15 AM
Lessons learned from Day 2 of interacting with NHS 111, trying to get 1 question answered: what's the fastest pathway to get an epi-pen as the #MastCell flares are intensifying? (It seems wise precaution as it takes nearly 3 mins before 111 pick up [yes, I'll call 999 if it happens. Many wouldn't])
Lessons learned about UK medical services from today's MCAS throat swelling rapid-spreading rash scare:
1 The word anaphylaxis doesn't cause a GP to phone you back even when they treated you for MCAS rash a week ago & gave you heavy-duty Fexofenadine Hydrochloride & you say you're alone & housebound
January 25, 2025 at 1:48 PM
Fellow #MastCell sufferers - any tips? What do you do to calm flare as fast as possible? (Currently rash on upper arms that is slowlyish spreading to lower arms. Feel otherwise healthy, usual EDS pain aside) Am hydrating w/ water/not eating anything else or using cleaning/scented products #CripCoop
Help urgently needed, #Medicsky #NEISvoid. I accidentally took a single ginger shot w/ apple juice on it w/ 180mg Fexofenadine (didn't think about ginger juice containing apple). Now having Mast cell skin reaction on arms & don't want anaphylaxis as no epi pen. Am hydrating. Feel fine otherwise. 1/2
January 24, 2025 at 3:25 PM
After years of being dismissed, I was finally diagnosed with HSD (7/9 Beighton). Doc suspects hEDS + Mast Cell too. I knew my body,and I’m finally being heard.
Endless love to #SpoonieSky for helping me feel seen through it all.

#ChronicIllness #hEDS #HSD #DisabilitySky #MastCell #POTS
April 30, 2025 at 6:51 PM
and tryptase levels increased in human FMS skin samples compared to healthy controls. Taken together our results suggests that FMS IgG mediates hypersensitivity via activation of mast cells bearing the MRGPRX2 receptor and that these cells are a potential therapeutic target.

#Fibromyalgia #MastCell
October 6, 2025 at 4:09 PM
#Mastcell modulation: A novel therapeutic strategy for abdominal #pain in #IBS irritable bowel syndrome
www.sciencedirect.com/science/arti...
March 15, 2025 at 3:57 PM