We may have 200,000+ structures by AlphaFold, but nothing beats the excitement of a day that starts like this! #crystallography #proteinstructure #science
October 12, 2023 at 9:18 AM
We may have 200,000+ structures by AlphaFold, but nothing beats the excitement of a day that starts like this! #crystallography #proteinstructure #science
Protein function depends on dynamic conformational changes. Patrick Barth &co present AlloPool, a #DeepLearning framework that reveals how protein motions give rise to biological function across diverse systems. 🧪 #ProteinStructure buff.ly/sTHTDBQ
September 25, 2026 at 4:30 PM
Protein function depends on dynamic conformational changes. Patrick Barth &co present AlloPool, a #DeepLearning framework that reveals how protein motions give rise to biological function across diverse systems. 🧪 #ProteinStructure buff.ly/sTHTDBQ
Protein function depends on dynamic conformational changes. Patrick Barth &co present AlloPool, a #DeepLearning framework that reveals how protein motions give rise to biological function across diverse systems. 🧪 #ProteinStructure buff.ly/sTHTDBQ
September 24, 2026 at 8:01 AM
Protein function depends on dynamic conformational changes. Patrick Barth &co present AlloPool, a #DeepLearning framework that reveals how protein motions give rise to biological function across diverse systems. 🧪 #ProteinStructure buff.ly/sTHTDBQ
#BOSC2025 keynote speaker Christine Orengo shared insights from the development of TED and CATH (which just hit its 30th birthday!). #ProteinStructure #ISMBECCB2025
July 21, 2025 at 1:48 PM
#BOSC2025 keynote speaker Christine Orengo shared insights from the development of TED and CATH (which just hit its 30th birthday!). #ProteinStructure #ISMBECCB2025
Protein function depends on dynamic conformational changes. Patrick Barth &co present AlloPool, a #DeepLearning framework that reveals how protein motions give rise to biological function across diverse systems. 🧪 #ProteinStructure buff.ly/sTHTDBQ
September 22, 2026 at 1:05 PM
Protein function depends on dynamic conformational changes. Patrick Barth &co present AlloPool, a #DeepLearning framework that reveals how protein motions give rise to biological function across diverse systems. 🧪 #ProteinStructure buff.ly/sTHTDBQ
Weekending using shaders from @blenderkit.bsky.social
Concept inspired by @bradyajohnston.bsky.social
Dynein arms — the ATP-powered engines behind ciliary motion.
#Dynein #Cilia #Axoneme #MolecularBiology #StructuralBiology #CryoEM #ProteinStructure #Biophysics #Blender3D #SciArt #BioArt
Concept inspired by @bradyajohnston.bsky.social
Dynein arms — the ATP-powered engines behind ciliary motion.
#Dynein #Cilia #Axoneme #MolecularBiology #StructuralBiology #CryoEM #ProteinStructure #Biophysics #Blender3D #SciArt #BioArt
February 21, 2026 at 4:20 PM
Weekending using shaders from @blenderkit.bsky.social
Concept inspired by @bradyajohnston.bsky.social
Dynein arms — the ATP-powered engines behind ciliary motion.
#Dynein #Cilia #Axoneme #MolecularBiology #StructuralBiology #CryoEM #ProteinStructure #Biophysics #Blender3D #SciArt #BioArt
Concept inspired by @bradyajohnston.bsky.social
Dynein arms — the ATP-powered engines behind ciliary motion.
#Dynein #Cilia #Axoneme #MolecularBiology #StructuralBiology #CryoEM #ProteinStructure #Biophysics #Blender3D #SciArt #BioArt
Enzymes, geometry, and big data in Liverpool!
@rhackett.bsky.social presented his project at #ISMBECCB2025, showcasing matching of catalytic motifs for enzyme function prediction.
#StructuralBioinformatics #EnzymeFunction #CatalyticMotifs
#ProteinStructure #EMBL #LUMC
@rhackett.bsky.social presented his project at #ISMBECCB2025, showcasing matching of catalytic motifs for enzyme function prediction.
#StructuralBioinformatics #EnzymeFunction #CatalyticMotifs
#ProteinStructure #EMBL #LUMC
July 22, 2025 at 4:09 PM
Enzymes, geometry, and big data in Liverpool!
@rhackett.bsky.social presented his project at #ISMBECCB2025, showcasing matching of catalytic motifs for enzyme function prediction.
#StructuralBioinformatics #EnzymeFunction #CatalyticMotifs
#ProteinStructure #EMBL #LUMC
@rhackett.bsky.social presented his project at #ISMBECCB2025, showcasing matching of catalytic motifs for enzyme function prediction.
#StructuralBioinformatics #EnzymeFunction #CatalyticMotifs
#ProteinStructure #EMBL #LUMC
Join the ProSE Seminar Series! A monthly discussion on the #Evolution of #ProteinStructure 🧪
Next up: Andrei Lupas
“Highly repetitive genomic ORFs: a source of new fibrous proteins?”
11th February | 3 PM GMT
🔗 Register here: tinyurl.com/prose-seminar1
Next up: Andrei Lupas
“Highly repetitive genomic ORFs: a source of new fibrous proteins?”
11th February | 3 PM GMT
🔗 Register here: tinyurl.com/prose-seminar1
January 29, 2025 at 9:44 AM
Join the ProSE Seminar Series! A monthly discussion on the #Evolution of #ProteinStructure 🧪
Next up: Andrei Lupas
“Highly repetitive genomic ORFs: a source of new fibrous proteins?”
11th February | 3 PM GMT
🔗 Register here: tinyurl.com/prose-seminar1
Next up: Andrei Lupas
“Highly repetitive genomic ORFs: a source of new fibrous proteins?”
11th February | 3 PM GMT
🔗 Register here: tinyurl.com/prose-seminar1
#AlphaFold #ProteinStructure vs metal sponge scrubber for dishes, find the difference :)
April 4, 2025 at 7:45 AM
#AlphaFold #ProteinStructure vs metal sponge scrubber for dishes, find the difference :)
🚀 Ready for discussion of “Balancing Rigor, Interpretability & Innovation: Desiderata for Biological Representation Learning" with:
🔹 Jean-Philippe Vert #drugdiscovery
🔹 Catherine Tong #proteinstructure
🔹 Daniel Burkhardt #multiscalebiology
🔹 Tim Stuart #singlecells
🔹 Mor Nitzan #cellmodelling
❓
🔹 Jean-Philippe Vert #drugdiscovery
🔹 Catherine Tong #proteinstructure
🔹 Daniel Burkhardt #multiscalebiology
🔹 Tim Stuart #singlecells
🔹 Mor Nitzan #cellmodelling
❓
February 17, 2025 at 2:00 PM
🚀 Ready for discussion of “Balancing Rigor, Interpretability & Innovation: Desiderata for Biological Representation Learning" with:
🔹 Jean-Philippe Vert #drugdiscovery
🔹 Catherine Tong #proteinstructure
🔹 Daniel Burkhardt #multiscalebiology
🔹 Tim Stuart #singlecells
🔹 Mor Nitzan #cellmodelling
❓
🔹 Jean-Philippe Vert #drugdiscovery
🔹 Catherine Tong #proteinstructure
🔹 Daniel Burkhardt #multiscalebiology
🔹 Tim Stuart #singlecells
🔹 Mor Nitzan #cellmodelling
❓
Read the paper in @natbiotech.nature.com: doi.org/10.1038/s415...
#AlphaFold #ExperimentGuidedAlphaFold #MachineLearning #StructuralPrediction #ProteinDynamics #ProteinStructure
#AlphaFold #ExperimentGuidedAlphaFold #MachineLearning #StructuralPrediction #ProteinDynamics #ProteinStructure
doi.org
June 29, 2026 at 9:01 AM
NALCN/Cch1 channelosome subunits originated in early eukaryotes. New study from Adriano Senatore @utoronto.ca and colleagues: rupress.org/jgp/article/...
#Lipids #membranes #MolecularPhysiology #ProteinStructure #ProteinDynamics #CellBiology #Evolution #IonChannels
#Lipids #membranes #MolecularPhysiology #ProteinStructure #ProteinDynamics #CellBiology #Evolution #IonChannels
September 12, 2025 at 2:15 PM
NALCN/Cch1 channelosome subunits originated in early eukaryotes. New study from Adriano Senatore @utoronto.ca and colleagues: rupress.org/jgp/article/...
#Lipids #membranes #MolecularPhysiology #ProteinStructure #ProteinDynamics #CellBiology #Evolution #IonChannels
#Lipids #membranes #MolecularPhysiology #ProteinStructure #ProteinDynamics #CellBiology #Evolution #IonChannels
Key Parkinson's Protein Structure And Malfunction Revealed For First Time #Science #HealthandMedicine #Neurology #ParkinsonsDisease #ProteinStructure #Neuroscience
Key Parkinson's Protein Structure And Malfunction Revealed For First Time
Solving a decades-long mystery.
purescience.news
March 16, 2025 at 8:00 AM
Key Parkinson's Protein Structure And Malfunction Revealed For First Time #Science #HealthandMedicine #Neurology #ParkinsonsDisease #ProteinStructure #Neuroscience
🚀 New paper in @natmethods.nature.com!
We present OpenStructure's powerful scoring capabilities, used to assess predictionsin CAMEO and CASP.
Read the full study here:
🔗 doi.org/10.1038/s415...
#StructuralBiology #Bioinformatics #OpenStructure #CASP #CAMEO #ProteinStructure
We present OpenStructure's powerful scoring capabilities, used to assess predictionsin CAMEO and CASP.
Read the full study here:
🔗 doi.org/10.1038/s415...
#StructuralBiology #Bioinformatics #OpenStructure #CASP #CAMEO #ProteinStructure
doi.org
December 23, 2025 at 3:18 PM
🚀 New paper in @natmethods.nature.com!
We present OpenStructure's powerful scoring capabilities, used to assess predictionsin CAMEO and CASP.
Read the full study here:
🔗 doi.org/10.1038/s415...
#StructuralBiology #Bioinformatics #OpenStructure #CASP #CAMEO #ProteinStructure
We present OpenStructure's powerful scoring capabilities, used to assess predictionsin CAMEO and CASP.
Read the full study here:
🔗 doi.org/10.1038/s415...
#StructuralBiology #Bioinformatics #OpenStructure #CASP #CAMEO #ProteinStructure
📝 Online now - the Review "Decoding protein structures with residue interaction networks" from Silvio Tosatto et al.
#RIN #ProteinStructure #ResidueCentrality #Allosterism #ArtificialIntelligence
Read it here: authors.elsevier.com/sd/article/S...
#RIN #ProteinStructure #ResidueCentrality #Allosterism #ArtificialIntelligence
Read it here: authors.elsevier.com/sd/article/S...
September 15, 2025 at 3:51 PM
📝 Online now - the Review "Decoding protein structures with residue interaction networks" from Silvio Tosatto et al.
#RIN #ProteinStructure #ResidueCentrality #Allosterism #ArtificialIntelligence
Read it here: authors.elsevier.com/sd/article/S...
#RIN #ProteinStructure #ResidueCentrality #Allosterism #ArtificialIntelligence
Read it here: authors.elsevier.com/sd/article/S...
DEADLINE EXTENDED: The new deadline for submission of manuscripts for this special issue is 31 January 2025.
📝 Call for Papers: Special Issue on "AlphaFold in Protein Structure and Function Prediction".
🔗https://www.csbj.org/call_AlphaFold
#AlphaFold #ProteinStructure #ProteinFunction
📝 Call for Papers: Special Issue on "AlphaFold in Protein Structure and Function Prediction".
🔗https://www.csbj.org/call_AlphaFold
#AlphaFold #ProteinStructure #ProteinFunction
December 7, 2024 at 8:51 AM
DEADLINE EXTENDED: The new deadline for submission of manuscripts for this special issue is 31 January 2025.
📝 Call for Papers: Special Issue on "AlphaFold in Protein Structure and Function Prediction".
🔗https://www.csbj.org/call_AlphaFold
#AlphaFold #ProteinStructure #ProteinFunction
📝 Call for Papers: Special Issue on "AlphaFold in Protein Structure and Function Prediction".
🔗https://www.csbj.org/call_AlphaFold
#AlphaFold #ProteinStructure #ProteinFunction
Happy New Year 2026! 🎆
Peace, Joy & Discovery in 2026! 🌿🔬
#happynewyear2026 #newyear2026 #ramachandranplot #proteinstructure #biophysicss #ComputationalChemistry #structuralbiology #scienceart #scicomm #sciencelane
Peace, Joy & Discovery in 2026! 🌿🔬
#happynewyear2026 #newyear2026 #ramachandranplot #proteinstructure #biophysicss #ComputationalChemistry #structuralbiology #scienceart #scicomm #sciencelane
December 31, 2025 at 8:07 PM
Happy New Year 2026! 🎆
Peace, Joy & Discovery in 2026! 🌿🔬
#happynewyear2026 #newyear2026 #ramachandranplot #proteinstructure #biophysicss #ComputationalChemistry #structuralbiology #scienceart #scicomm #sciencelane
Peace, Joy & Discovery in 2026! 🌿🔬
#happynewyear2026 #newyear2026 #ramachandranplot #proteinstructure #biophysicss #ComputationalChemistry #structuralbiology #scienceart #scicomm #sciencelane
Exciting opportunity to see the main authors of Boltz-1 (Jeremy Wohlwend and Gabriele Corso @gcorso.bsky.social) present at #MIT on Thurs, Dec 5. Boltz-1 was shown to achieve SOTA performance at the level of AlphaFold3
#AlphaFold #drugdiscovery #proteinstructure
jclinic.mit.edu/events/boltz...
#AlphaFold #drugdiscovery #proteinstructure
jclinic.mit.edu/events/boltz...
Boltz-1 Seminar – MIT Jameel Clinic
jclinic.mit.edu
December 2, 2024 at 6:00 PM
Exciting opportunity to see the main authors of Boltz-1 (Jeremy Wohlwend and Gabriele Corso @gcorso.bsky.social) present at #MIT on Thurs, Dec 5. Boltz-1 was shown to achieve SOTA performance at the level of AlphaFold3
#AlphaFold #drugdiscovery #proteinstructure
jclinic.mit.edu/events/boltz...
#AlphaFold #drugdiscovery #proteinstructure
jclinic.mit.edu/events/boltz...
Last week to apply! #PhD #Chromatin #StemCells #ProteinStructure #Enhancers #Transcription #LineageCommitment
Funded PhD Studentship available in my lab at @lsiexeter.bsky.social.
Want to study how chromatin remodellers act on enhancers to facilitate cell fate decisions in human pluripotent cells? Want to work and live in a lively city by the sea? Get in touch/Apply!
lsi.exeter.ac.uk/groups/hendr...
Want to study how chromatin remodellers act on enhancers to facilitate cell fate decisions in human pluripotent cells? Want to work and live in a lively city by the sea? Get in touch/Apply!
lsi.exeter.ac.uk/groups/hendr...
Hendrich Group - Starting Sept 2025 - Living Systems Institute - University of Exeter
Opportunity for LSI PHD studentship – starting in September 2025 or January 2026 PhD Studentship applications will open on 1st...
lsi.exeter.ac.uk
June 2, 2025 at 9:18 AM
Last week to apply! #PhD #Chromatin #StemCells #ProteinStructure #Enhancers #Transcription #LineageCommitment
Fully funded (at UK home rate) #PhD studentships to start 2025/2026 at University of Exeter, UK. #Chromatin #StemCells #Signalling #ProteinStructure #LineageCommitment #Transcription
Please spread the word, and anyone interested please contact me.
lsi.exeter.ac.uk/groups/hendr...
Please spread the word, and anyone interested please contact me.
lsi.exeter.ac.uk/groups/hendr...
Hendrich Group - Starting Sept 2025 - Living Systems Institute - University of Exeter
LSI PHD studentship – start September 2025 or January 2026 Project 1: Title of Project: Control of chromatin remodeller activity...
lsi.exeter.ac.uk
March 29, 2025 at 8:11 AM
Fully funded (at UK home rate) #PhD studentships to start 2025/2026 at University of Exeter, UK. #Chromatin #StemCells #Signalling #ProteinStructure #LineageCommitment #Transcription
Please spread the word, and anyone interested please contact me.
lsi.exeter.ac.uk/groups/hendr...
Please spread the word, and anyone interested please contact me.
lsi.exeter.ac.uk/groups/hendr...
Exploring voltage-gated sodium channel conformations and protein-protein interactions using #AlphaFold2. New study from Diego Lopez-Mateos, Kush Narang, & Vladimir Yarov-Yarovoy (@vyy-sf.bsky.social) @ucd-physiology.bsky.social: rupress.org/jgp/article/...
#ProteinStructure #Biophysics #IonChannels
#ProteinStructure #Biophysics #IonChannels
December 25, 2025 at 8:01 PM
Exploring voltage-gated sodium channel conformations and protein-protein interactions using #AlphaFold2. New study from Diego Lopez-Mateos, Kush Narang, & Vladimir Yarov-Yarovoy (@vyy-sf.bsky.social) @ucd-physiology.bsky.social: rupress.org/jgp/article/...
#ProteinStructure #Biophysics #IonChannels
#ProteinStructure #Biophysics #IonChannels
One of the things that I am looking in at the moment is AlphaFold and protein structure and function prediction. So let me know your good, bad and everyting in between experiences.
#PlantScience #AlphaFold #ProteinStructure #Science
#PlantScience #AlphaFold #ProteinStructure #Science
November 14, 2024 at 8:34 AM
One of the things that I am looking in at the moment is AlphaFold and protein structure and function prediction. So let me know your good, bad and everyting in between experiences.
#PlantScience #AlphaFold #ProteinStructure #Science
#PlantScience #AlphaFold #ProteinStructure #Science
we tried to fill this gap in knowledge, by:
1) identifying conserved proteins by #ProteinFolding & matching #FoldSeek
2) review their roles & #ProteinStructure #AlphaFold3
3) Propose a model for the G+ T4SS from #Enterococcus
Check out our work to learn more!
#StructuralBioinformatics #AIinScience
1) identifying conserved proteins by #ProteinFolding & matching #FoldSeek
2) review their roles & #ProteinStructure #AlphaFold3
3) Propose a model for the G+ T4SS from #Enterococcus
Check out our work to learn more!
#StructuralBioinformatics #AIinScience
authors.elsevier.com
January 16, 2025 at 8:46 AM
we tried to fill this gap in knowledge, by:
1) identifying conserved proteins by #ProteinFolding & matching #FoldSeek
2) review their roles & #ProteinStructure #AlphaFold3
3) Propose a model for the G+ T4SS from #Enterococcus
Check out our work to learn more!
#StructuralBioinformatics #AIinScience
1) identifying conserved proteins by #ProteinFolding & matching #FoldSeek
2) review their roles & #ProteinStructure #AlphaFold3
3) Propose a model for the G+ T4SS from #Enterococcus
Check out our work to learn more!
#StructuralBioinformatics #AIinScience
Learn about #AI tools in #protein #science, including design and engineering, at the EMBO Practical Course "AI for protein design" in Puerto Varas, Chile, 3–9 November 2025.
Deadline: 1 August
meetings.embo.org/event/25-ai-...
#LifeSciences #research #training #ProteinStructure #EMBOevents 🧪
Deadline: 1 August
meetings.embo.org/event/25-ai-...
#LifeSciences #research #training #ProteinStructure #EMBOevents 🧪
AI for protein design
In the last 5 years, the scientific community has witnessed the development of several AI-based tools for groundbreaking advances in protein science. These tools have enabled scientists to predict pr…
meetings.embo.org
July 7, 2025 at 12:07 PM
Learn about #AI tools in #protein #science, including design and engineering, at the EMBO Practical Course "AI for protein design" in Puerto Varas, Chile, 3–9 November 2025.
Deadline: 1 August
meetings.embo.org/event/25-ai-...
#LifeSciences #research #training #ProteinStructure #EMBOevents 🧪
Deadline: 1 August
meetings.embo.org/event/25-ai-...
#LifeSciences #research #training #ProteinStructure #EMBOevents 🧪
A critical residue mediates proper assembly and gating of GIRK2 channels. New study from Ha Nguyen, Paul A. Slesinger and colleagues @sinaibrain.bsky.social: rupress.org/jgp/article/...
#Biochemistry #MolecularPharmacology #ProteinStructure #ProteinDynamics #Biophysics #IonChannels
#Biochemistry #MolecularPharmacology #ProteinStructure #ProteinDynamics #Biophysics #IonChannels
December 26, 2025 at 3:15 PM
A critical residue mediates proper assembly and gating of GIRK2 channels. New study from Ha Nguyen, Paul A. Slesinger and colleagues @sinaibrain.bsky.social: rupress.org/jgp/article/...
#Biochemistry #MolecularPharmacology #ProteinStructure #ProteinDynamics #Biophysics #IonChannels
#Biochemistry #MolecularPharmacology #ProteinStructure #ProteinDynamics #Biophysics #IonChannels