#DiabeticNephropathy
PAI1/SERPINE1 mediates Paracrine Senescence of renal tubular epithelial cells (TGFβ1 + high glucose)
Blocked by TM5441, PAI1 Inhibitor
#SciRep 2023
www.nature.com/articles/s41...
PAI1/SERPINE1 mediates Paracrine Senescence of renal tubular epithelial cells (TGFβ1 + high glucose)
Blocked by TM5441, PAI1 Inhibitor
#SciRep 2023
www.nature.com/articles/s41...
April 20, 2026 at 7:03 PM
#DiabeticNephropathy
PAI1/SERPINE1 mediates Paracrine Senescence of renal tubular epithelial cells (TGFβ1 + high glucose)
Blocked by TM5441, PAI1 Inhibitor
#SciRep 2023
www.nature.com/articles/s41...
PAI1/SERPINE1 mediates Paracrine Senescence of renal tubular epithelial cells (TGFβ1 + high glucose)
Blocked by TM5441, PAI1 Inhibitor
#SciRep 2023
www.nature.com/articles/s41...
Painting by Dr. Tiff Caza! @glombandit.bsky.social #ArtofMedicine #CKDAwareness #DiabeticNephropathy
March 6, 2025 at 9:07 PM
Painting by Dr. Tiff Caza! @glombandit.bsky.social #ArtofMedicine #CKDAwareness #DiabeticNephropathy
A nationwide register-based cohort study examined the association between #preeclampsia in mothers and the risk of #kidneydisease in their offspring
doi.org/10.1016/j.kint.2025.04.017
#OpenAccess #chronickidneydisease #CKD #Glomerulonephritis #PedsNeph #NephSky #MedSky #diabeticnephropathy
doi.org/10.1016/j.kint.2025.04.017
#OpenAccess #chronickidneydisease #CKD #Glomerulonephritis #PedsNeph #NephSky #MedSky #diabeticnephropathy
May 20, 2025 at 2:02 PM
A nationwide register-based cohort study examined the association between #preeclampsia in mothers and the risk of #kidneydisease in their offspring
doi.org/10.1016/j.kint.2025.04.017
#OpenAccess #chronickidneydisease #CKD #Glomerulonephritis #PedsNeph #NephSky #MedSky #diabeticnephropathy
doi.org/10.1016/j.kint.2025.04.017
#OpenAccess #chronickidneydisease #CKD #Glomerulonephritis #PedsNeph #NephSky #MedSky #diabeticnephropathy
Reversal of advanced diabetic kidney disease in mice treated with a monoclonal anti-VEGFR1 antibody
doi.org/10.1016/j.kint.2026.03.016
#NephSky #MedSky #OpenAccess #diabeticnephropathy
@usc.edu
doi.org/10.1016/j.kint.2026.03.016
#NephSky #MedSky #OpenAccess #diabeticnephropathy
@usc.edu
April 30, 2026 at 9:38 PM
Reversal of advanced diabetic kidney disease in mice treated with a monoclonal anti-VEGFR1 antibody
doi.org/10.1016/j.kint.2026.03.016
#NephSky #MedSky #OpenAccess #diabeticnephropathy
@usc.edu
doi.org/10.1016/j.kint.2026.03.016
#NephSky #MedSky #OpenAccess #diabeticnephropathy
@usc.edu
Interesting evidence that FGF9 protects high glucose-induced EMT in vitro
FGF9⏬in human #DiabeticNephropathy
A possible Exosomal circRNA-miRNA-FGF9 regulatory axis (in silico only, needs experimental validation)
@plosone.org 2025
journals.plos.org/plosone/arti...
FGF9⏬in human #DiabeticNephropathy
A possible Exosomal circRNA-miRNA-FGF9 regulatory axis (in silico only, needs experimental validation)
@plosone.org 2025
journals.plos.org/plosone/arti...
November 28, 2025 at 8:00 PM
Interesting evidence that FGF9 protects high glucose-induced EMT in vitro
FGF9⏬in human #DiabeticNephropathy
A possible Exosomal circRNA-miRNA-FGF9 regulatory axis (in silico only, needs experimental validation)
@plosone.org 2025
journals.plos.org/plosone/arti...
FGF9⏬in human #DiabeticNephropathy
A possible Exosomal circRNA-miRNA-FGF9 regulatory axis (in silico only, needs experimental validation)
@plosone.org 2025
journals.plos.org/plosone/arti...
Improving the Histologic Classification of Advanced Diabetic Nephropathy Based on the Transformative Research in #DiabeticNephropathy (TRIDENT) Findings
doi.org/10.1016/j.kint.2026.07.028
#NephSky #MedSky #OpenAccess @upenn.edu @cedarssinaihsu.bsky.social @yale.edu #DiabeticNephropathy #PathSky
doi.org/10.1016/j.kint.2026.07.028
#NephSky #MedSky #OpenAccess @upenn.edu @cedarssinaihsu.bsky.social @yale.edu #DiabeticNephropathy #PathSky
September 3, 2026 at 4:29 PM
Improving the Histologic Classification of Advanced Diabetic Nephropathy Based on the Transformative Research in #DiabeticNephropathy (TRIDENT) Findings
doi.org/10.1016/j.kint.2026.07.028
#NephSky #MedSky #OpenAccess @upenn.edu @cedarssinaihsu.bsky.social @yale.edu #DiabeticNephropathy #PathSky
doi.org/10.1016/j.kint.2026.07.028
#NephSky #MedSky #OpenAccess @upenn.edu @cedarssinaihsu.bsky.social @yale.edu #DiabeticNephropathy #PathSky
ℹ️ New Review out!
Current trends in single-cell RNA sequencing applications in diabetes mellitus
👉 buff.ly/1R29Yi1
#DiabetesMellitus #scRNAseq #DiabeticNephropathy
Current trends in single-cell RNA sequencing applications in diabetes mellitus
👉 buff.ly/1R29Yi1
#DiabetesMellitus #scRNAseq #DiabeticNephropathy
July 2, 2025 at 9:33 AM
ℹ️ New Review out!
Current trends in single-cell RNA sequencing applications in diabetes mellitus
👉 buff.ly/1R29Yi1
#DiabetesMellitus #scRNAseq #DiabeticNephropathy
Current trends in single-cell RNA sequencing applications in diabetes mellitus
👉 buff.ly/1R29Yi1
#DiabetesMellitus #scRNAseq #DiabeticNephropathy
Proteinase 3 Drives Murine Diabetic Kidney Disease by Mediating Caspase-3-dependent Apoptosis of Podocytes
doi.org/10.1016/j.kint.2026.02.020
#MedSky #NephSky #OpenAccess #diabetes #diabeticnephropathy
doi.org/10.1016/j.kint.2026.02.020
#MedSky #NephSky #OpenAccess #diabetes #diabeticnephropathy
March 27, 2026 at 2:37 AM
Proteinase 3 Drives Murine Diabetic Kidney Disease by Mediating Caspase-3-dependent Apoptosis of Podocytes
doi.org/10.1016/j.kint.2026.02.020
#MedSky #NephSky #OpenAccess #diabetes #diabeticnephropathy
doi.org/10.1016/j.kint.2026.02.020
#MedSky #NephSky #OpenAccess #diabetes #diabeticnephropathy
Clinical and Histologic Predictors of Non-Diabetic Kidney Disease in Patients with Diabetes Mellitus
doi.org/10.1016/j.kint.2026.03.015
#NephSky #MedSky #OpenAccess #diabeticnephropathy
@arkanalabs.bsky.social @stanforddeptmed.bsky.social
@jhu.edu
doi.org/10.1016/j.kint.2026.03.015
#NephSky #MedSky #OpenAccess #diabeticnephropathy
@arkanalabs.bsky.social @stanforddeptmed.bsky.social
@jhu.edu
April 30, 2026 at 9:25 PM
Clinical and Histologic Predictors of Non-Diabetic Kidney Disease in Patients with Diabetes Mellitus
doi.org/10.1016/j.kint.2026.03.015
#NephSky #MedSky #OpenAccess #diabeticnephropathy
@arkanalabs.bsky.social @stanforddeptmed.bsky.social
@jhu.edu
doi.org/10.1016/j.kint.2026.03.015
#NephSky #MedSky #OpenAccess #diabeticnephropathy
@arkanalabs.bsky.social @stanforddeptmed.bsky.social
@jhu.edu
Is #preeclampsia ever “mild?” Lessons on long-term consequences for offspring from a Danish registry–based study
Commentary by S Jesudason & G Piccoli
doi.org/10.1016/j.kint.2025.05.011
Original article: doi.org/10.1016/j.kint.2025.04.017
#MedSky #NephSky #CKD #diabeticnephropathy #PedsNeph
Commentary by S Jesudason & G Piccoli
doi.org/10.1016/j.kint.2025.05.011
Original article: doi.org/10.1016/j.kint.2025.04.017
#MedSky #NephSky #CKD #diabeticnephropathy #PedsNeph
August 19, 2025 at 4:30 PM
Is #preeclampsia ever “mild?” Lessons on long-term consequences for offspring from a Danish registry–based study
Commentary by S Jesudason & G Piccoli
doi.org/10.1016/j.kint.2025.05.011
Original article: doi.org/10.1016/j.kint.2025.04.017
#MedSky #NephSky #CKD #diabeticnephropathy #PedsNeph
Commentary by S Jesudason & G Piccoli
doi.org/10.1016/j.kint.2025.05.011
Original article: doi.org/10.1016/j.kint.2025.04.017
#MedSky #NephSky #CKD #diabeticnephropathy #PedsNeph
This review outlines recent progress in treating #DiabeticNephropathy via drugs and molecules targeting the #mTORpathway, offering insights for improved prevention and therapy. #medsky
#OpenAccess: www.sciencedirect.com/science/arti...
#OpenAccess: www.sciencedirect.com/science/arti...
November 10, 2025 at 4:15 PM
This review outlines recent progress in treating #DiabeticNephropathy via drugs and molecules targeting the #mTORpathway, offering insights for improved prevention and therapy. #medsky
#OpenAccess: www.sciencedirect.com/science/arti...
#OpenAccess: www.sciencedirect.com/science/arti...
#FGF9 renal mRNA (2 RNAseq datasets), renal (glomerular + tubular) protein (IHC), serum level (49 case vs 51 ctrl)⬇️in👤#DiabeticNephropathy
FGF9 protein⬇️in kidney glomeruli & tubule (IHC) in STZ diabetic🐭
FGF9⏬hi glucose-induced #EMT
#JCellMolMed 2025
onlinelibrary.wiley.com/doi/10.1111/...
FGF9 protein⬇️in kidney glomeruli & tubule (IHC) in STZ diabetic🐭
FGF9⏬hi glucose-induced #EMT
#JCellMolMed 2025
onlinelibrary.wiley.com/doi/10.1111/...
October 28, 2025 at 7:11 PM
#FGF9 renal mRNA (2 RNAseq datasets), renal (glomerular + tubular) protein (IHC), serum level (49 case vs 51 ctrl)⬇️in👤#DiabeticNephropathy
FGF9 protein⬇️in kidney glomeruli & tubule (IHC) in STZ diabetic🐭
FGF9⏬hi glucose-induced #EMT
#JCellMolMed 2025
onlinelibrary.wiley.com/doi/10.1111/...
FGF9 protein⬇️in kidney glomeruli & tubule (IHC) in STZ diabetic🐭
FGF9⏬hi glucose-induced #EMT
#JCellMolMed 2025
onlinelibrary.wiley.com/doi/10.1111/...
#DiabeticNephropathy
Endothelial Cell FGF13 (a non-secreted FGF) as a Parkin-#Mitophagy inhibitor▶️Mitochondrial dysfunction▶️
⏫Glomerular EC Apoptosis
⏬Glomerular endothelial fenestration
⏫Glomerular Fibrosis
⏫Renal injury
in Diabetic🐭
#Diabetes_ADA 2023
diabetesjournals.org/diabetes/art...
Endothelial Cell FGF13 (a non-secreted FGF) as a Parkin-#Mitophagy inhibitor▶️Mitochondrial dysfunction▶️
⏫Glomerular EC Apoptosis
⏬Glomerular endothelial fenestration
⏫Glomerular Fibrosis
⏫Renal injury
in Diabetic🐭
#Diabetes_ADA 2023
diabetesjournals.org/diabetes/art...
December 16, 2025 at 12:53 PM
#DiabeticNephropathy
Endothelial Cell FGF13 (a non-secreted FGF) as a Parkin-#Mitophagy inhibitor▶️Mitochondrial dysfunction▶️
⏫Glomerular EC Apoptosis
⏬Glomerular endothelial fenestration
⏫Glomerular Fibrosis
⏫Renal injury
in Diabetic🐭
#Diabetes_ADA 2023
diabetesjournals.org/diabetes/art...
Endothelial Cell FGF13 (a non-secreted FGF) as a Parkin-#Mitophagy inhibitor▶️Mitochondrial dysfunction▶️
⏫Glomerular EC Apoptosis
⏬Glomerular endothelial fenestration
⏫Glomerular Fibrosis
⏫Renal injury
in Diabetic🐭
#Diabetes_ADA 2023
diabetesjournals.org/diabetes/art...
Heterogeneity in the relationships between #albuminuria and glomerular structure in type 1 and type 2 #diabetes.
doi.org/10.1016/j.kint.2025.08.034
#NephySky #MedSky #diabetes #diabeticnephropathy
@uwdeptmedicine.bsky.social
doi.org/10.1016/j.kint.2025.08.034
#NephySky #MedSky #diabetes #diabeticnephropathy
@uwdeptmedicine.bsky.social
October 9, 2025 at 3:54 PM
Heterogeneity in the relationships between #albuminuria and glomerular structure in type 1 and type 2 #diabetes.
doi.org/10.1016/j.kint.2025.08.034
#NephySky #MedSky #diabetes #diabeticnephropathy
@uwdeptmedicine.bsky.social
doi.org/10.1016/j.kint.2025.08.034
#NephySky #MedSky #diabetes #diabeticnephropathy
@uwdeptmedicine.bsky.social
Restoration of branched chain amino acid catabolism improves kidney function in preclinical cardiovascular-kidney- #metabolicsyndrome models
doi.org/10.1016/j.kint.2025.04.025
#OpenAccess #Nephsky #MedSky #chronickidneydisease #CKD #diabeticnephropathy #cardiovasculardisease #CVD #kidney
doi.org/10.1016/j.kint.2025.04.025
#OpenAccess #Nephsky #MedSky #chronickidneydisease #CKD #diabeticnephropathy #cardiovasculardisease #CVD #kidney
May 22, 2025 at 2:31 PM
Restoration of branched chain amino acid catabolism improves kidney function in preclinical cardiovascular-kidney- #metabolicsyndrome models
doi.org/10.1016/j.kint.2025.04.025
#OpenAccess #Nephsky #MedSky #chronickidneydisease #CKD #diabeticnephropathy #cardiovasculardisease #CVD #kidney
doi.org/10.1016/j.kint.2025.04.025
#OpenAccess #Nephsky #MedSky #chronickidneydisease #CKD #diabeticnephropathy #cardiovasculardisease #CVD #kidney
Commentary
Renal biopsy in patients with diabetes: still going strong after all these years
doi.org/10.1016/j.kint.2026.05.003
Original article: doi.org/10.1016/j.kint.2026.03.015
#MedSky #NephSky #PathSky #DiabeticNephropathy #KidneyBiopsy #NonDiabeticKidneyDisease #NDKD #RenalPath
Renal biopsy in patients with diabetes: still going strong after all these years
doi.org/10.1016/j.kint.2026.05.003
Original article: doi.org/10.1016/j.kint.2026.03.015
#MedSky #NephSky #PathSky #DiabeticNephropathy #KidneyBiopsy #NonDiabeticKidneyDisease #NDKD #RenalPath
August 12, 2026 at 3:49 PM
Commentary
Renal biopsy in patients with diabetes: still going strong after all these years
doi.org/10.1016/j.kint.2026.05.003
Original article: doi.org/10.1016/j.kint.2026.03.015
#MedSky #NephSky #PathSky #DiabeticNephropathy #KidneyBiopsy #NonDiabeticKidneyDisease #NDKD #RenalPath
Renal biopsy in patients with diabetes: still going strong after all these years
doi.org/10.1016/j.kint.2026.05.003
Original article: doi.org/10.1016/j.kint.2026.03.015
#MedSky #NephSky #PathSky #DiabeticNephropathy #KidneyBiopsy #NonDiabeticKidneyDisease #NDKD #RenalPath
Amir Abdipour from #LomaLindaUniversityMedicalCenter discusses his study on the alignment of AI models with nephrologists when answering patient questions about #diabeticnephropathy.
Watch now: www.youtube.com/watch?v=yqDP...
Read the full article: diabetes.jmir.org/2025/1/e65846/
#AI #LLU
Watch now: www.youtube.com/watch?v=yqDP...
Read the full article: diabetes.jmir.org/2025/1/e65846/
#AI #LLU
AI vs. Nephrologists: Diabetic Nephropathy Q&A
This video reviews a cross-sectional study comparing how artificial intelligence models like ChatGPT and Google Gemini align with nephrologists when answerin...
www.youtube.com
June 23, 2025 at 2:04 PM
Amir Abdipour from #LomaLindaUniversityMedicalCenter discusses his study on the alignment of AI models with nephrologists when answering patient questions about #diabeticnephropathy.
Watch now: www.youtube.com/watch?v=yqDP...
Read the full article: diabetes.jmir.org/2025/1/e65846/
#AI #LLU
Watch now: www.youtube.com/watch?v=yqDP...
Read the full article: diabetes.jmir.org/2025/1/e65846/
#AI #LLU
Protein UHRF1-mediated dual dysregulation of molecular chaperone GRP78 induces endoplasmic reticulum stress and aggravates #diabeticnephropathy
doi.org/10.1016/j.kint.2025.07.023
#MedSky #NephSky #OpenAccess
doi.org/10.1016/j.kint.2025.07.023
#MedSky #NephSky #OpenAccess
September 3, 2025 at 2:39 PM
Protein UHRF1-mediated dual dysregulation of molecular chaperone GRP78 induces endoplasmic reticulum stress and aggravates #diabeticnephropathy
doi.org/10.1016/j.kint.2025.07.023
#MedSky #NephSky #OpenAccess
doi.org/10.1016/j.kint.2025.07.023
#MedSky #NephSky #OpenAccess
This #STTT review summarizes the complex mechanisms underlying the #pathophysiology of #DiabeticNephropathy (DN), outlining recent advances in diagnostic & therapeutic strategies and future directions for managing DN. #medsky
#OpenAccess: doi.org/10.1038/s413...
#OpenAccess: doi.org/10.1038/s413...
August 23, 2025 at 4:30 AM
This #STTT review summarizes the complex mechanisms underlying the #pathophysiology of #DiabeticNephropathy (DN), outlining recent advances in diagnostic & therapeutic strategies and future directions for managing DN. #medsky
#OpenAccess: doi.org/10.1038/s413...
#OpenAccess: doi.org/10.1038/s413...
Discover how #Rutin and #Glimepiride synergistically manage #DiabeticNephropathy, improving #glycemiccontrol and renal health in STZ-diabetic models.
Explore more at bio-integration.org/managing-dia...
#BIOI #DiabetesResearch #Science @scienceopen.bsky.social #sciencejournal
Explore more at bio-integration.org/managing-dia...
#BIOI #DiabetesResearch #Science @scienceopen.bsky.social #sciencejournal
Rutin and Glimepiride Combination: A Novel Approach for Managing Diabetes Nephropathy in Streptozotocin Induced Diabetes in Wistar Rats
Announcing a new article publication for BIO Integration journal. Diabetes mellitus remains a global health concern, because of its associated complications, including diabetic nephropathy. Glimepirid...
bio-integration.org
December 4, 2024 at 7:11 AM
Discover how #Rutin and #Glimepiride synergistically manage #DiabeticNephropathy, improving #glycemiccontrol and renal health in STZ-diabetic models.
Explore more at bio-integration.org/managing-dia...
#BIOI #DiabetesResearch #Science @scienceopen.bsky.social #sciencejournal
Explore more at bio-integration.org/managing-dia...
#BIOI #DiabetesResearch #Science @scienceopen.bsky.social #sciencejournal
This bibliometric analysis discusses mTOR signaling-associated pathological mechanisms in various renal cell types within a #diabetic environment & highlights the therapeutic implications of targeting the #mTORpathway in #DiabeticNephropathy. #medsky
#OpenAccess: www.sciencedirect.co...
#OpenAccess: www.sciencedirect.co...
February 25, 2025 at 11:00 PM
This bibliometric analysis discusses mTOR signaling-associated pathological mechanisms in various renal cell types within a #diabetic environment & highlights the therapeutic implications of targeting the #mTORpathway in #DiabeticNephropathy. #medsky
#OpenAccess: www.sciencedirect.co...
#OpenAccess: www.sciencedirect.co...
PDGFRβ+ #MesangialCell Lats1/2 KO->
⏫MC prolifer
⏫#GlomerularFibrosis
⏬#GlomerularBarrier
Mimicking #DiabeticNephropathy
Rescued by YAP/TAZ KO
High glucose->⏫YAP/TAZ->⏫N-Myc, not C-Myc
Dr. Kyung Pyo Kang, Gou Young Koh labs #JASN 2023
journals.lww.com/jasn/Citatio...
⏫MC prolifer
⏫#GlomerularFibrosis
⏬#GlomerularBarrier
Mimicking #DiabeticNephropathy
Rescued by YAP/TAZ KO
High glucose->⏫YAP/TAZ->⏫N-Myc, not C-Myc
Dr. Kyung Pyo Kang, Gou Young Koh labs #JASN 2023
journals.lww.com/jasn/Citatio...
September 2, 2023 at 11:47 AM
PDGFRβ+ #MesangialCell Lats1/2 KO->
⏫MC prolifer
⏫#GlomerularFibrosis
⏬#GlomerularBarrier
Mimicking #DiabeticNephropathy
Rescued by YAP/TAZ KO
High glucose->⏫YAP/TAZ->⏫N-Myc, not C-Myc
Dr. Kyung Pyo Kang, Gou Young Koh labs #JASN 2023
journals.lww.com/jasn/Citatio...
⏫MC prolifer
⏫#GlomerularFibrosis
⏬#GlomerularBarrier
Mimicking #DiabeticNephropathy
Rescued by YAP/TAZ KO
High glucose->⏫YAP/TAZ->⏫N-Myc, not C-Myc
Dr. Kyung Pyo Kang, Gou Young Koh labs #JASN 2023
journals.lww.com/jasn/Citatio...
What is the Link Between Diabetes and Kidney Disease?
#ACEinhibitors #ARBs #artificialintelligence #biomarkers #BloodSugarControl #chronickidneydisease #CKD #diabetes #diabeticnephropathy #dialysis #GeneticStudies #GFR #glomerularfiltrationrate #Hypertension
thediabeticwriter.com/?p=6293
#ACEinhibitors #ARBs #artificialintelligence #biomarkers #BloodSugarControl #chronickidneydisease #CKD #diabetes #diabeticnephropathy #dialysis #GeneticStudies #GFR #glomerularfiltrationrate #Hypertension
thediabeticwriter.com/?p=6293
July 19, 2024 at 5:30 PM
What is the Link Between Diabetes and Kidney Disease?
#ACEinhibitors #ARBs #artificialintelligence #biomarkers #BloodSugarControl #chronickidneydisease #CKD #diabetes #diabeticnephropathy #dialysis #GeneticStudies #GFR #glomerularfiltrationrate #Hypertension
thediabeticwriter.com/?p=6293
#ACEinhibitors #ARBs #artificialintelligence #biomarkers #BloodSugarControl #chronickidneydisease #CKD #diabetes #diabeticnephropathy #dialysis #GeneticStudies #GFR #glomerularfiltrationrate #Hypertension
thediabeticwriter.com/?p=6293
This study shows that Xiaoke decoction (XKD) protects #RenalFunction in #DiabeticNephropathy (DN) via the #COX 2–mediated #LDLr pathway, reducing #Inflammation & #LipidAccumulation, highlighting XKD as a potent #therapeutic approach for DN. #medsky
See: doi.org/10.1007/s115...
See: doi.org/10.1007/s115...
April 22, 2026 at 1:00 PM
This study shows that Xiaoke decoction (XKD) protects #RenalFunction in #DiabeticNephropathy (DN) via the #COX 2–mediated #LDLr pathway, reducing #Inflammation & #LipidAccumulation, highlighting XKD as a potent #therapeutic approach for DN. #medsky
See: doi.org/10.1007/s115...
See: doi.org/10.1007/s115...
#USP19 promotes high glucose– and fatty acid–induced kidney cell dysfunction by stabilizing TAK1, driving #apoptosis, mitochondrial stress, and PINK1/Parkin pathway disruption, highlighting USP19–TAK1 signaling as a target for #DiabeticNephropathy.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
February 18, 2026 at 1:55 PM
#USP19 promotes high glucose– and fatty acid–induced kidney cell dysfunction by stabilizing TAK1, driving #apoptosis, mitochondrial stress, and PINK1/Parkin pathway disruption, highlighting USP19–TAK1 signaling as a target for #DiabeticNephropathy.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...