#ginsenoside
Dengue virus lacks specific #Antivirals; R18, a #ginsenoside from Panax notoginseng, acts as a dual E/RdRp inhibitor, blocking viral adsorption, entry, and replication while attenuating disease in mouse models. #medsky #Virology
#AMM #OpenAccess: doi.org/10.15212/AMM...
September 24, 2026 at 11:08 AM
A time-delayed bHLH pair regulates ginsenoside biosynthesis

Huang et al.

nph.onlinelibrary.wiley.com/share/PKISET...
June 15, 2026 at 2:35 PM
Ginsenoside Rd protects against early brain injury after hemorrhage by inhibiting ferroptosis through the cGAS/STING pathway.

by Jiang GY, Yang HR (...) Gao C et 10 al. in Free Radic Biol Med #MedSky

📖 read the article:
Ginsenoside Rd alleviates early brain injury by inhibiting ferroptosis through cGAS/STING/DHODH pathway after subarachnoid hemorrhage
Ferroptosis, a recently identified form of regulated cell death, is characterized by lipid peroxidation and iron accumulation, plays a critical role i…
www.sciencedirect.com
January 9, 2025 at 8:33 AM
Ginsenoside Rh2 from Red Ginseng reduces inflammation by blocking TLR4 dimerization and key immune pathways

www.thailandmedical.news/news/ginseno...
Ginsenoside Rh2 from Red Ginseng reduces inflammation by blocking TLR4 dimerization and key immune pathways - Thailand Medical News
www.thailandmedical.news
September 3, 2024 at 1:25 AM
🦠 A new FASEB Journal review dives into how ginsenoside Rk3 from Panax ginseng may modulate gut microbiota—boosting diversity, reshaping function, and offering therapeutic promise.
🔗 buff.ly/v18X8Pt
#Microbiome #GutHealth #FASEBJournal
July 23, 2025 at 6:29 PM
Discover: Ginseng's embryonic protoderm efficiently produces ginsenosides, overcoming long growth cycles. Single-cell transcriptome shows high accumulation, boosting potential. PMID:42350386, Nat Commun 2026, @NatureComms https://doi.org/10.1038/s41467-026-74881-5 #Medsky #Pharmsky #RNA #ASHG 🧪
Single-cell analyses identify the ginseng embryonic protoderm as a native compartment for high-efficiency ginsenoside production | Nature Communications
Ginseng (Panax ginseng) derives its renowned therapeutic properties from ginsenoside metabolites. However, the long cultivation cycle and susceptibility to diseases hinder the advancement of the ginseng industry. Here, we demonstrate that the embryonic protoderm of ginseng can efficiently produce ginsenosides. Single-cell transcriptome and mass spectrometry imaging analyses reveal that ginsenosides accumulate in the protoderm of ginseng embryonic callus (EC) at levels comparable to those in forest ginseng. Epigenetic analyses indicate that elevated histone acetylation and enhanced chromatin accessibility at regeneration- and ginsenoside metabolism-related gene loci are associated with the ginsenoside-producing capacity of EC. Increasing histone acetylation levels or overexpressing the regeneration-related WUSCHEL-RELATED HOMEOBOX11 (WOX11) gene further enhances ginsenoside production in EC. Our findings suggest that the protoderm of EC could serve as an in situ biological compartment f
doi.org
September 17, 2026 at 3:00 PM
Ginsenoside Rg1 ameliorates the senescence and neurite injury of retinal ganglion cells in DR via targeting VDR and promoting mitochondrial biogenesis
www.sciencedirect.com/science/arti...
June 28, 2025 at 2:40 PM
We concluded that Rg1 exerts its anti-aging effects through SSE1-mediated mitophagy. This study advances our understanding of Rg1-mediated mitophagy and mitochondrial regulation via SSE1.
Ginsenoside Rg1 delays chronological aging in a yeast model via SSE1-Mediated mitophagy
Ginsenoside Rg1 (Rg1), an active compound in Panax ginseng C. A. Meyer (ginseng), has shown potential to ameliorate age-related cell damage and extend…
www.sciencedirect.com
December 25, 2025 at 5:39 AM
🌿🧪 New article in @aobp.bsky.social analyzing the molecular regulation of saponin biosynthesis and age-related variation in ginsenoside content in Panax japonicus rhizomes.

Full #openaccess
👉 doi.org/10.1093/aobp...

#PlantScience
September 9, 2025 at 6:07 AM
👏 Targeting ferroptosis in NASH

🧐 A bioactive ginsenoside alleviates hepatocellular ferroptosis induced by oxidized phospholipid accumulation in nonalcoholic steatohepatitise.
#NASH #Ferroptosis #LiverDisease #Metabolism
onlinelibrary.wiley.com/doi/10.1002/...
A bioactive ginsenoside alleviates hepatocellular ferroptosis induced by oxidized phospholipid accumulation in nonalcoholic steatohepatitis
Schematic representation showing that 20 (S)-Rg3 improves mouse NASH. 20(S)-Rg3 reduces OxPLs levels and ameliorates ferroptosis in the liver of NASH mice. Mechanistically, 20(S)-Rg3 activates SPOP. ...
onlinelibrary.wiley.com
March 6, 2026 at 8:25 AM
ATCC's resource, RRID:CVCL_0125, was just reported to be used in "Simultaneous co-delivery of Ginsenoside Rg3 and Imiquimod from PLGA nanoparticles for effective breast cancer immunotherapy". RRIDs like this improve reproducibility in scientific research. #reproducibility #reproducibility
doi.org
April 10, 2025 at 7:00 AM
Ginsenoside Rg1: A natural triterpenoid glycoside with promising anti-depressive properties
www.sciencedirect.com/science/arti...
January 17, 2025 at 11:02 AM
Pharmacokinetics and tissue distribution analysis of ginsenoside Rh3 in rats using a novel LC-MS/MS quantification strategy #FrontPharmacol www.frontiersin.org/journals/pha...
Frontiers | Pharmacokinetics and tissue distribution analysis of ginsenoside Rh3 in rats using a novel LC-MS/MS quantification strategy
Introduction:Ginsenoside Rh3 (GRh3), a rare ginsenoside, demonstrates diverse pharmacological activities in vitro; however, the lack of pharmacokinetic and t...
www.frontiersin.org
July 26, 2025 at 4:42 AM
Research progress on anti-aging effects and mechanisms of the new ginsenoside Compound K
www.sciencedirect.com/science/arti...
February 18, 2025 at 12:57 PM
Increased removal of ginsenoside Rb1 through the application of capacitance-enhanced biochars in soils.
✅Removes 90% of #ginsenoside Rb1 (a harmful root toxin) in 84 hours!
✅Slashes fungal pathogens by up to 17.18%.
#Agricultural #soil, #Electron transfer.
link.springer.com/article/10.1...
April 1, 2025 at 5:41 AM
Modified Biochar Reduces Pathogenic Fungi by Up to 17.18% and Enhances Ginsenoside Rb1 Removal

ift.tt/VqUorsP
March 25, 2025 at 9:26 PM
New #CJNM study: R-Ginsenoside Rg3 protects the gut during chemotherapy by repairing cell recycling systems. 🧪
🧬 A vital boost for patient recovery!
🔗 Full details: doi.org/10.1016/S187...
#Oncology #Chemotherapy #Ginseng #DrugSafety #CJNM
May 12, 2026 at 1:15 PM
#PaperoftheDay: "Exploring the anti-atherosclerosis mechanism of ginsenoside Rb1 by integrating network pharmacology and experimental verification"

DOI ⬇️
doi.org/10.18632/agi...

#aging #research #openaccess #gerontology #peerreview #journal #publishing
Exploring the anti-atherosclerosis mechanism of ginsenoside Rb1 by integrating network pharmacology and experimental verification | Aging
Ginsenoside Rb1 is the major active constituent of ginseng, which is widely used in traditional Chinese medicine for the atherosclerosis treatment by anti-inflammatory, anti-oxidant and reducing lipid
doi.org
May 29, 2026 at 1:32 PM
RRIDs were included in this in Free Radical Biology and Medicine paper. We value the author's support of reproducibility. #ReproducibleResearch #STMpublishing #OpenResearch
Ginsenoside Rh1 sensitizes gastric cancer to cuproptosis and represses immune evasion
Read the full paper: Ginsenoside Rh1 sensitizes gastric cancer to cuproptosis and represses immune evasion
doi.org
March 27, 2026 at 7:00 AM
A Diploid Panax Genome Reveals Ginsenoside Diversity Driven by UGT Diversification and Network Rewiring, Rather Than Gene Family Expansion https://www.biorxiv.org/content/10.64898/2026.06.16.732563v1
June 22, 2026 at 3:32 AM
Ok, so vegan biomimetic collagen (so not actually collagen itself but the bundled building blocks that let the body build its own collagen) look to be more effective than animal sources. So I can avoid the animal products totally, yay! www.sciencedirect.com/science/arti...
Oral supplementation of vegan collagen biomimetic has beneficial effects on human skin physiology: A double-blind, placebo-controlled study
Vegan collagen is an innovative plant-based collagen biomimetic that contains a variety of plant extracts, including asiaticoside, ginsenoside, and th…
www.sciencedirect.com
January 9, 2026 at 6:39 PM
#Ginsenoside Rb1 protects BMECs from #Ischemia-reperfusion injury by regulating #Autophagy, #Apoptosis, and #OxidativeStress via SQSTM1/p62, ATG5, and HIF-1α, highlighting these as potential #TherapeuticTargets for #IschemicStroke.
Read: doi.org/10.1007/s115...
February 6, 2026 at 2:01 PM
RRID:AB_2879236 from @proteintech.bsky.social was used by authors in their Journal of Neuroinflammation paper. We value the author's support of reproducibility. #STMpublishing #RRID #BetterScience
Ginsenoside Rg2 attenuates secondary brain injury following intracerebral hemorrhage by inhibiting NLRP3-mediated pyroptosis - Journal of Neuroinflammation
Read the full paper: Ginsenoside Rg2 attenuates secondary brain injury following intracerebral hemorrhage by inhibiting NLRP3-mediated pyroptosis
doi.org
May 10, 2026 at 7:01 AM
Ginsenoside Re binds Drp1 Leu94 across species to restore mitochondrial homeostasis via Atg1/ULK1-dependent fission-mitophagy coupling in age-related degeneration
www.sciencedirect.com/science/arti...
November 22, 2025 at 1:47 PM