##ProteinStructure
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pawthonlabs.bsky.social
For 50 years, scientists struggled to predict how a protein folds into its 3D shape. Then DeepMind’s AlphaFold did it with near-lab accuracy, from the amino acid sequence alone.

#ProteinFolding #ProteinStructure #AIBreakthrough #ArtificialIntelligence #MachineLearning
youtube.com/shorts/ZZoNZ...
The AI That Solved a 50-Year Biology Problem
YouTube video by Pawthon Labs
youtube.com
November 1, 2026 at 4:00 PM
claudiaalcar.bsky.social
TEDLH is now searchable online! Paste your protein sequence and detect remote homologues across 4,600+ CATH superfamilies. Results are annotated and linked to experimentally determined PDB structures.
Give it a try!
🔗 tedlh-cs.cathdb.info
#Bioinformatics #ProteinStructure @cathgene3d.bsky.social
October 19, 2026 at 11:56 AM
plosbiology.org
Protein function depends on dynamic conformational changes. Patrick Barth &co present AlloPool, a #DeepLearning framework that reveals how protein motions give rise to biological function across diverse systems. 🧪 #ProteinStructure buff.ly/sTHTDBQ
PDZ3 protein structure with peptide agonist binding site highlighted in cyan, an allosteric loop in red, and purple lines tracing the binding path; right panels show WT conformations with a green arrow for enhanced and red arrow for decreased allosteric coupling.
September 25, 2026 at 4:30 PM
plosbiology.org
Protein function depends on dynamic conformational changes. Patrick Barth &co present AlloPool, a #DeepLearning framework that reveals how protein motions give rise to biological function across diverse systems. 🧪 #ProteinStructure buff.ly/sTHTDBQ
PDZ3 protein structure with peptide agonist binding site highlighted in cyan, an allosteric loop in red, and purple lines tracing the binding path; right panels show WT conformations with a green arrow for enhanced and red arrow for decreased allosteric coupling.
September 24, 2026 at 8:01 AM
plosbiology.org
Protein function depends on dynamic conformational changes. Patrick Barth &co present AlloPool, a #DeepLearning framework that reveals how protein motions give rise to biological function across diverse systems. 🧪 #ProteinStructure buff.ly/sTHTDBQ
PDZ3 protein structure with peptide agonist binding site highlighted in cyan, an allosteric loop in red, and purple lines tracing the binding path; right panels show WT conformations with a green arrow for enhanced and red arrow for decreased allosteric coupling.
September 22, 2026 at 1:05 PM
proseandpassion.mastodon.social.ap.brid.gy
11-Sep-2026
Uniting sequence and structure to map the protein universe
A new #protein language model combines #sequence and #structure information to reveal relationships across billions of years of #evolution

https://www.eurekalert.org/news-releases/1142950

#science #nanoworld […]
Original post on mastodon.social
mastodon.social
September 11, 2026 at 3:44 PM
jgp.org
New review: Prantl, Atzgerstorfer, Derler et al. @jku.at catalog known disease-associated #Orai1 mutations, explain how they disrupt the activation sequence, and link them to their clinical impact. rupress.org/jgp/article/...

#IonChannels #Biophysics #ProteinStructure #MembraneTransport
August 31, 2026 at 4:01 PM
rupress.org
New review @jgp.org: Prantl, Atzgerstorfer, Derler et al. @jku.at catalog known disease-associated #Orai1 mutations, explain how they disrupt the activation sequence, and link them to their clinical impact. rupress.org/jgp/article/...

#IonChannels #Biophysics #ProteinStructure #MembraneTransport
August 31, 2026 at 4:45 PM
mapjournals.bsky.social
#gCommo
eGPS-oneBuilder integrates multi-method phylogenetic inference with Foldseek-based protein structure clustering, enabling quantitative tree comparison for gene-family evolution.
Details: https://www.maxapress.com/article/doi/10.48130/gcomm-0026-0015
#Phylogenetics #ProteinStructure
August 14, 2026 at 12:47 AM
jgp.org
Reorganization of the slide helix by cholesterol during KirBac1.1 channel inactivation in #membranes. New study from Arpan Bysack and H. Raghuraman (Saha Institute of Nuclear Physics, Kolkata):
rupress.org/jgp/article/...

#ProteinStructure #MembraneTransport #Biophysics #IonChannels
August 13, 2026 at 8:45 PM
scholarcast.bsky.social
This work develops solid-state NMR strategy to characterize disordered regions in amyloid fibrils linked to neurodegenerative diseases. doi.org/10.52601/bpr... #Biophysics #SolidStateNMR #ProteinStructure #Neurodegeneration
July 10, 2026 at 11:41 AM
woody-sherman.bsky.social
Exciting opportunity to see the main authors of Boltz-1 (Jeremy Wohlwend and Gabriele Corso @gcorso.bsky.social) present at #MIT on Thurs, Dec 5. Boltz-1 was shown to achieve SOTA performance at the level of AlphaFold3
#AlphaFold #drugdiscovery #proteinstructure
jclinic.mit.edu/events/boltz...
Boltz-1 Seminar – MIT Jameel Clinic
jclinic.mit.edu
December 2, 2024 at 6:00 PM
enginyapici.bsky.social
𝗬𝗼𝘂 𝗰𝗮𝗻 𝗻𝗼𝘄 𝘄𝗮𝘁𝗰𝗵 𝗺𝗼𝗹𝗲𝗰𝘂𝗹𝗲𝘀 𝗰𝗵𝗮𝗻𝗴𝗲 𝘀𝗵𝗮𝗽𝗲 𝗶𝗻 𝗿𝗲𝗮𝗹 𝘁𝗶𝗺𝗲.

It measures how long a single molecule stays trapped, and turns that into size, shape, and binding data. No freezing, no tethering, no guessing.

medium.com/@enginyapici...

#Biotech #DrugDiscovery #ProteinStructure #StructuralBiology
You Can Now Watch Molecules Change Shape in Real Time
We finally have a way to measure structural change in solution, in real time, without freezing, tethering, or guessing.
medium.com
May 12, 2025 at 6:17 PM
csbj.org
🔗 SpheronizaTor: Spherical Voxelization for Interpretable Protein Microenvironment Modeling. doi.org/10.34133/csb...

📚 CSBJ - A Science Partner Journal: spj.science.org/journal/csbj

#StructuralBiology #Bioinformatics #ComputationalBiology #ProteinStructure #ProteinEngineering #ProteinModeling
🔗 SpheronizaTor: Spherical Voxelization for Interpretable Protein Microenvironment Modeling. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0076 📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj
May 10, 2026 at 2:09 PM
csbj.org
🧠 Can post-processing and deep learning push protein prediction to near perfection?

🔗 Post-processing enhances protein secondary structure prediction with second order deep learning and embeddings. DOI: doi.org/10.1016/j.cs...

📚 CSBJ: www.csbj.org

#PSSP #ProteinStructure #ProtBERT #AlphaFold #AI
Post-processing enhances protein secondary structure prediction with second order deep learning and embeddings. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2024.12.022
April 16, 2025 at 1:03 AM
csbj.org
DEADLINE EXTENDED: The new deadline for submission of manuscripts for this special issue is 31 January 2025.

📝 Call for Papers: Special Issue on "AlphaFold in Protein Structure and Function Prediction".

🔗https://www.csbj.org/call_AlphaFold

#AlphaFold #ProteinStructure #ProteinFunction
December 7, 2024 at 8:51 AM
proseandpassion.mastodon.social.ap.brid.gy
16-Sep-2025
Better understanding of #bitter #taste receptors: An AlphaFold3-based structure study
Researchers use an advanced AI-based prediction model, #alphafold 3, to predict the structure of human bitter taste #receptors
https://www.eurekalert.org/news-releases/1098406

#science #humans […]
Original post on mastodon.social
mastodon.social
September 19, 2025 at 2:38 PM
uwmedchem.bsky.social
Excellent update today from Mason Saunders, #PhD Candidate in the Kelly Lee Lab at the UW SOP #MedChem Dept.
More here: tinyurl.com/Saunders520

#CryoET #CryoEM
#virus #research
#StructuralBiology
#ProteinStructure
#birdflu #H5N1
#StandWithScience
@uwmedchem.bsky.social
@uwpharmacy.bsky.social
Mason Saunders, UWMedChem PhD Candidate gave us an update on his current… | UWMedChem
Mason Saunders, UWMedChem PhD Candidate gave us an update on his current research in the Kelly Lee Lab at the University of Washington today: “Characterizing the impact of stalk length on H5N1 neurami...
www.linkedin.com
May 29, 2025 at 8:18 PM
echoexplorers91.bsky.social
Wgu C785 Final Exam Study Guide Amino Acids Protein Structure 2024 2025 Edition
#Wgu #C785 #WguC785 #AminoAcids #nursing #ProteinStructure #wgu2026 #wguquestionsandanswers #hackedexams

www.hackedexams.com/item/62419/w...
February 17, 2026 at 12:21 PM
surfinnurd.bsky.social
Last week to apply! #PhD #Chromatin #StemCells #ProteinStructure #Enhancers #Transcription #LineageCommitment
surfinnurd.bsky.social Surfin' NuRD @surfinnurd.bsky.social · Apr 12
Funded PhD Studentship available in my lab at @lsiexeter.bsky.social.
Want to study how chromatin remodellers act on enhancers to facilitate cell fate decisions in human pluripotent cells? Want to work and live in a lively city by the sea? Get in touch/Apply!
lsi.exeter.ac.uk/groups/hendr...
Hendrich Group - Starting Sept 2025 - Living Systems Institute - University of Exeter
Opportunity for LSI PHD studentship – starting in September 2025 or January 2026 PhD Studentship applications will open on 1st...
lsi.exeter.ac.uk
June 2, 2025 at 9:18 AM
surfinnurd.bsky.social
Fully funded (at UK home rate) #PhD studentships to start 2025/2026 at University of Exeter, UK. #Chromatin #StemCells #Signalling #ProteinStructure #LineageCommitment #Transcription

Please spread the word, and anyone interested please contact me.

lsi.exeter.ac.uk/groups/hendr...
Hendrich Group - Starting Sept 2025 - Living Systems Institute - University of Exeter
LSI PHD studentship – start September 2025 or January 2026 Project 1: Title of Project: Control of chromatin remodeller activity...
lsi.exeter.ac.uk
March 29, 2025 at 8:11 AM
genesdev.bsky.social
⏪ G&D RECAP ⏪

🗓️ October 2025
RESEARCH COMMUNICATION: Structural basis of nucleosome recognition by the conserved Dsup & HMGN nucleosome-binding motif
By Alegrio-Louro et al. and Andres Leschziner
➡️ https://genesdev.cshlp.org/content/39/19-20/1155.full

#proteininteractions #proteinstructure #cryoEM
December 29, 2025 at 7:00 PM
plantenzo.bsky.social
One of the things that I am looking in at the moment is AlphaFold and protein structure and function prediction. So let me know your good, bad and everyting in between experiences.
#PlantScience #AlphaFold #ProteinStructure #Science
November 14, 2024 at 8:34 AM
mtyka.bsky.social
Wow 🤯 - my former post doc advisor David Baker won the Nobel Prize for Protein Design. Huge congrats - well deserved! David and his lab have been a force of nature in protein design. Incredible watching the progress over the last 20 years. #NobelPrize2024 #proteindesign #ProteinStructure
October 10, 2024 at 7:13 PM
the-14.com
I was a beta tester for the Nobel prize-winning AlphaFold AI – it’s going to revolutionise health research
#AI #Chemistry #Health #AlphaFold #NobelPrize #HealthResearch #ProteinStructure #Biotechnology #DrugDiscovery #AIinScience #MolecularBiology
the-14.com/i-was-a-beta...
I was a beta tester for the Nobel prize-winning AlphaFold AI – it’s going to revolutionise health research | The-14
As a beta tester for the Nobel-winning AlphaFold AI, I’ve seen how it can predict protein structures in minutes,revolutionizing health research & drug discovery
the-14.com
October 15, 2024 at 2:35 PM