#CellPolarity
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yashunsky.bsky.social
Our @natphys.nature.com paper is now out!
We find that defect creation & annihilation in bacteria and cells collectives spontaneously break mirror symmetry—unpredicted by active nematic theory.
#softmatter #chiral #ActiveMatter #TopologicalDefects #LivingMatter #CellPolarity

rdcu.be/yWTRbT26p9qa
September 6, 2026 at 8:06 AM
rink-lab.bsky.social
Proud to announce our epos on the multi-scale coordination of #cellpolarity and #planarcellpolarity at Featuring the formidable first authors @Soor88 and @meo0205, @TheGeneMyers and Azimzadeh labs and #planaria, of course. And 6 years of hard work :)
August 14, 2026 at 4:01 PM
sandraiden.bsky.social
today at noon! #CellPolarity, #CellMigration, #DGZ, #CellBiology
dgz.bsky.social DGZ.bsky.social @dgz.bsky.social · Jan 20
Please join us for the next #DGZ #FocusWorkshop, this time on #CellPolarity and #CellMigration, Jan. 28, noon (CET) via zoom, organized by Virginie Lecaudey and Markus Engstler, featuring talks by James Cleland, Maja Matis, Anton Aebischer & Scott C. Dawson!
January 28, 2025 at 8:38 AM
dgz.bsky.social
On April 28, we will come together for the next #DGZ Focus Workshop on #cellpolarity & #cellmigration, organized by Virginie Lecaudey & Markus Engstler. Talks by
@srishti-rangarajan.bsky.social, @rocha-lab.bsky.social, @marta-shahbazi.bsky.social, @xaviertrepat.bsky.social. Join us!
April 8, 2026 at 10:32 AM
dgz.bsky.social
Please join us for the next #DGZ #FocusWorkshop, this time on #CellPolarity and #CellMigration, Jan. 28, noon (CET) via zoom, organized by Virginie Lecaudey and Markus Engstler, featuring talks by James Cleland, Maja Matis, Anton Aebischer & Scott C. Dawson!
January 20, 2025 at 11:08 AM
liedewijlaan.bsky.social
New paper out in EMBO Reports!
We show that Cdc42 regulation is oligomerization-dependent and that a GEF and a GAP act synergistically: Cdc24 relieves self-inhibition of oligomeric Rga2, enabling robust Cdc42 cycling.
doi.org/10.1038/s44319-026-00695-7
#cellpolarity #Cdc42 #synergy #syntheticbiology
Oligomerization-dependent and synergistic regulation of Cdc42 GTPase cycling by a GEF and a GAP - EMBO Reports
Cell polarity is a crucial biological process essential for cell division, directed growth, and motility. In Saccharomyces cerevisiae, polarity establishment centers around the small Rho-type GTPase C...
doi.org
February 22, 2026 at 6:26 PM
rcatanho.bsky.social
Defectos en la organización de la polaridad celular planar pueden participar en la patogénesis del síndrome de uña amarilla congénito y esporádico #yellownailsyndrome #cellpolarity www.acpjournals.org/doi/10.7326/...
Impaired Wnt/Planar Cell Polarity Signaling in Yellow Nail Syndrome | Annals of Internal Medicine
Background: Yellow nail syndrome (YNS) is a rare disorder characterized by a triad of yellow dystrophic nails, lymphedema, and chronic lung disease. Most patients present in adulthood, with only a few...
www.acpjournals.org
December 26, 2024 at 7:27 AM
harnoslab.bsky.social
🚀 Check out the newly improved Harnos Lab webpages!

Our research on cell polarity, development, and migration - now with a fresh look.

👉 ueb1.sci.muni.cz/ofiz/en/harn...

#CellPolarity #DevelopmentalBiology #Xenopus #WntSignaling
Harnos Lab - Section of Animal Physiology and Immunology
——– What we work withWe study early Xenopus frog embryos: a powerful model for developmental biology. 🐸 Why frogsTheir embryos are large, develop outside the body, and are ideal for live imaging and e...
ueb1.sci.muni.cz
January 6, 2026 at 11:50 AM
rootarchitecture.bsky.social
Introducing #ambassadorISRRWP6 B. Jazmin Reyes H. @bjazminrh.bsky.social
metabolism-dependent Arabidopsis roots dev. and dynamics of microtubules in lateral roots #cellpolarity #SOSEKI proteins #PlantGenetics #Molecular and #CellularBiology #Microscopy Currently in Persson’s lab Uni of Copenhagen
February 21, 2025 at 9:31 PM
genesndiseases.bsky.social
#PDE4DIP upregulation disrupts #cytoskeleton, #CellPolarity, and mitochondrial energy metabolism via Rho-ROCK signaling, driving the progression of #LVNC and highlighting a potential therapeutic target.
#OpenAccess: doi.org/10.1016/j.ge...
May 4, 2026 at 3:00 PM
genesndiseases.bsky.social
#PDE4DIP activation plays a critical role in #LeftVentricularNoncompaction development by regulating #cellpolarity, skeleton, and energy metabolism via the Rho-ROCK pathway, thereby offering potential targets and therapeutic strategies. #medsky

#OpenAccess:
www.sciencedirect.com
July 4, 2025 at 5:56 PM
genesndiseases.bsky.social
This study identifies #PDE4DIP as a key player in #LeftVentricularNoncompaction development by regulating #cellpolarity, skeleton, and energy metabolism via the Rho-ROCK pathway. #LVNC
Dysfunction of PDE4DIP contributes to LVNC development by regulating cell polarity, skeleton ec1
This study demonstrates that dysfunction of PDE4DIP contributes to the development of left ventricular non-compaction (LVNC) cardiomyopathy by disrupting cel...
youtube.com
June 25, 2025 at 5:18 AM
genesndiseases.bsky.social
Mechanistic insights into how PDE4DIP contributes to the #pathogenesis of left ventricular non-compaction (#LVNC) by regulating #CellPolarity, cytoskeleton architecture, & energy metabolism through the Rho-ROCK pathway. #cardiomyopathy #medsky

#OpenAccess: www.sciencedirect.com/science/arti...
Dysfunction of PDE4DIP contributes to LVNC development by regulating cell polarity, skeleton, and energy metabolism via Rho-ROCK pathway
April 7, 2025 at 2:00 PM
genesndiseases.bsky.social
Mechanistic insights into how PDE4DIP contributes to the #pathogenesis of left ventricular non-compaction (#LVNC) by regulating #CellPolarity, cytoskeleton architecture, & energy metabolism through the Rho-ROCK pathway. #cardiomyopathy #medsky

#OpenAccess: www.sciencedirect.co...
Dysfunction of PDE4DIP contributes to LVNC development by regulating cell polarity, skeleton, and energy metabolism via Rho-ROCK pathway
March 4, 2025 at 2:00 PM
apdu-unige.bsky.social
Two cells, one twist 🧬🔁
Myosin asymmetry breaks mirror symmetry & sparks spontaneous 3D rotations in doublets.
Adherens junctions🩶, focal adhesions🟢 & actomyosin🔴 Biology meets active matter physics.
#CellPolarity #Fluorescencefriday #ActiveMatter #Microscopy
May 2, 2025 at 2:02 PM
rupress.org
New in @jcb.org: Jarosińska, Boxem et al. @utrechtuniversity.bsky.social reveal how LGL-1 and PAC-1 team up to polarize the #Celegans embryo, providing new insight into how conserved #polarity mechanisms are adapted across species.
rupress.org/jcb/article/...

#CellPolarity #Genetics
May 6, 2026 at 2:30 PM
plosbiology.org
Cdc42 is a small GTPase crucial for #CellPolarity, but how does it contribute to #aging when upregulated? This study shows that the ER-anchored chaperone Ydj1 interacts with Cdc42, enhancing its stability & partitioning during asymm #CellDivision & aging in yeast @plosbiology.org 🧪 plos.io/4qz7WaM
Cdc42 accumulates in aged cells, and reducing its levels extends life span.Two representative WT cells expressing Cdc42-mCherrySW are shown at selected ages and time points (hr: min) from initial loading. White arrowheads indicate cells during or shortly after cytokinesis, when Cdc42 levels are quantified. Black and red arrowheads denote the same cells at other cell cycle stages and cell death, respectively. Scale bar: 3 µm.
February 16, 2026 at 9:05 AM
plosbiology.org
Cdc42 is a small GTPase crucial for #CellPolarity, but how does it contribute to #aging when upregulated? This study shows that the ER-anchored chaperone Ydj1 interacts with Cdc42, enhancing its stability & partitioning during asymm #CellDivision & aging in yeast @plosbiology.org 🧪 plos.io/4qz7WaM
Cdc42 accumulates in aged cells, and reducing its levels extends life span.Two representative WT cells expressing Cdc42-mCherrySW are shown at selected ages and time points (hr: min) from initial loading. White arrowheads indicate cells during or shortly after cytokinesis, when Cdc42 levels are quantified. Black and red arrowheads denote the same cells at other cell cycle stages and cell death, respectively. Scale bar: 3 µm.
February 13, 2026 at 5:35 PM
plosbiology.org
Cdc42 is a small GTPase crucial for #CellPolarity, but how does it contribute to #aging when upregulated? This study shows that the ER-anchored chaperone Ydj1 interacts with Cdc42, enhancing its stability & partitioning during asymm #CellDivision & aging in yeast @plosbiology.org 🧪 plos.io/4qz7WaM
Cdc42 accumulates in aged cells, and reducing its levels extends life span.Two representative WT cells expressing Cdc42-mCherrySW are shown at selected ages and time points (hr: min) from initial loading. White arrowheads indicate cells during or shortly after cytokinesis, when Cdc42 levels are quantified. Black and red arrowheads denote the same cells at other cell cycle stages and cell death, respectively. Scale bar: 3 µm.
February 13, 2026 at 2:05 PM
davidbryantlab.bsky.social
Delighted to move over to Bluesky. We are a #CellPolarity
lab using #3Dculture to study how cells collectively move in cancer @cruk-si.bsky.social. Give us a follow if you're into 3D culture, phosphoinositides or metastasis. Strong supporter of equality and helping pull folks up the ladder.
November 13, 2024 at 3:16 PM
jcb.org
Jarosińska, Boxem et al. @utrechtuniversity.bsky.social reveal how LGL-1 and PAC-1 team up to polarize the #Celegans embryo, providing new insight into how conserved #polarity mechanisms are adapted across species.
rupress.org/jcb/article/...

#CellPolarity #Genetics
May 5, 2026 at 4:45 PM
martin-belmontef.bsky.social
🧪 Canonical autophagy isn’t enough! In our new study, only CASM can coordinate the membrane remodeling needed to build a single lumen in tubes. Read how CASM drives endocytic recycling to drive morphogenesis www.biorxiv.org/content/10.1...
#ScienceTwitter #Autophagy #Morphogenesis #CellPolarity
Graphical model showing the effect of CASM autophagy in lumen resolution of epithelial tubes.
April 29, 2025 at 7:43 AM