#MastCells
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kjkrathwohl.bsky.social
The Clinical Relevance of Mast Cell Activation in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

#MastCells #MCAS #ME #MECFS
www.mdpi.com
November 10, 2025 at 5:59 AM
ohtwist.bsky.social
In which mast cells are found to not only emit lots of mediators, but occasionally ingest other white blood cells like neutrophils and either consume them, or emit their contents too...😮

www.sciencenews.org/article/some...

#MCAS #Masto #MastCells #Immunology #EDS #HSD #NEISvoid #MedSky
During an allergic response, some immune cells digest others
Mast cells lure and trap other immune cells during allergic reactions, using their compounds to increase inflammation in a process dubbed nexocytosis
www.sciencenews.org
December 13, 2024 at 12:34 AM
sabrinapoirier.bsky.social
#Doctors could display #humility and #curiosity when they don’t understand the chronic illness-fuelled chronic pain they see.

They could read up on things like #hypermobility, #mastcells, #glial cells, neuro #inflammation research, etc.

They could believe us when we say it’s a 9-10 today.
December 10, 2024 at 2:09 PM
drrebeccaryan.bsky.social
Thankyou. A fantastic article. #mastcells are responsible for the #visceralhypersensitivity we see in #IBS and #IBD. Antihistamines and mast cell stabilizers should be part of every gastro’s most used meds. Why amitryltiline works, it is an antihistamine.
heniek-htw.bsky.social htw @heniek-htw.bsky.social · Nov 17
Mast cell modulation: A novel therapeutic strategy for abdominal #pain in #IBD irritable bowel syndrome
www.sciencedirect.com/science/arti...
November 18, 2024 at 11:10 AM
regisjoulia.bsky.social
#SpatialBiology #Asthma #MastCells #Transcriptomics #LungImmunology #ImperialCollegeLondon

@britsocimm.bsky.social @natrevimmunol.nature.com @imperialnhli.bsky.social @10xgenomics.bsky.social @brukerspatial.bsky.social @nature.com @societymucosalimm.bsky.social @asthmaandlung.org.uk
May 21, 2025 at 4:40 PM
crazyus.com
I need a weird-health group to talk with about my weird health. I’m a little scared & maybe I don’t need to be scared. This is getting old. Talk me off the ledge.
💙🙏

#anemia
#Tryptasemia
#MastCells
#Inflammation
#MastCellActivationSyndrome
#IronInfusions
#PTSD
#ChronicIllness
#MaybeItsNothing
National Trust - Burlington Gap and the Seven Sisters, Eastbourne, United Kingdom
November 25, 2024 at 3:03 AM
jem.org
Salm, Lopez, Kubes et al. reveal that peritoneal #mastcells, activated by sensory neurons, extend #cytonemes that hand off extracellular condensate to neighboring #macrophages, driving rapid aggregation & a repair phenotype. rupress.org/jem/article/...

#Neuroimmunology #InnateImmunity #inflammation
July 22, 2026 at 4:16 PM
ohtwist.bsky.social
In which mast cells are found to not only emit lots of mediators, but occasionally ingest other white blood cells like neutrophils and either consume them, or emit their contents too...😮
www.sciencenews.org/article/some...

#MCAS #Masto #MastCells #Immunology #EDS #HSD #NEISvoid #MedSky #hEDS
During an allergic response, some immune cells digest others
Mast cells lure and trap other immune cells during allergic reactions, using their compounds to increase inflammation in a process dubbed nexocytosis
www.sciencenews.org
January 13, 2025 at 5:30 AM
ohtwist.bsky.social
In which mast cells are found to not only emit lots of mediators, but occasionally ingest other white blood cells like neutrophils and either consume them, or emit their contents too...😮
www.sciencenews.org/article/some...
#MCAS #Masto #MastCells #Immunology #EDS #HSD #NEISvoid #MedSky
During an allergic response, some immune cells digest others
Mast cells lure and trap other immune cells during allergic reactions, using their compounds to increase inflammation in a process dubbed nexocytosis
www.sciencenews.org
January 27, 2025 at 11:14 PM
renegaderesearch.bsky.social
Don't forget to register for our Clinician's Roundtable this Friday with neurogastroenterologist Dr. Zac Spiritos!

If you have #MastCells #MCAS #MACD #Mastocytosis #HaT #Histamine on the mind, you'll want to learn about the brain-gut connection and treating gastric impacts!

Register ⬇️ #MedSky
March 22, 2026 at 9:36 PM
danhkaplan.bsky.social
New paper from Kaplan Lab. Agonizing a specific glutamate receptor on mast cells in the skin renders them less function and can suppress several models of skin inflammation. Congrats to Youran Zhang and all co-authors. #skinimmunology #immunology #mastcells www.science.org/doi/10.1126/...
Agonism of the glutamate receptor GluK2 suppresses dermal mast cell activation and cutaneous inflammation
Small-molecule agonism of GluK2 reduces dermal mast cell responses to MrgprB2 ligation and suppresses skin inflammation.
www.science.org
December 11, 2024 at 7:06 PM
okuyanuzayli34.bsky.social
“Egzaman var diye krem sürüp duruyorsun ama sorun cildinde değil…

Egzama bir cilt sorunu değil.
Biyolojik olarak bağırsak bariyerinin çöküşüdür.

#egzama
#atopikdermatit
#gutskinning
#bağırsakbariyeri
#leakygut
#inflamasyon
#mastcells
#eczacıtavsiyesi
#ciltbilimi
#immunoloji
December 12, 2025 at 11:04 AM
ohtwist.bsky.social
Does Mast Cell Activation Underlie Multiple Ills? Unclear... Miriam E. Tucker via Medscape, October 2024

www.medscape.com/viewarticle/...

#EDS #MCAS #hEDS #HSD #POTS #Dysatuonomia #MastCells #Medicine #Science #Illness #ChronicIllness #NEISvoid #MedSky #Doctors #Zebras
Does Mast Cell Activation Syndrome Underlie Multiple Ills?
There is controversy over the diagnostic criteria, with one proposed definition placing it at the center of many other co-occurring complex, chronic illnesses.
www.medscape.com
November 13, 2024 at 4:41 AM
ohtwist.bsky.social
Does Mast Cell Activation Underlie Multiple Ills? Unclear... Miriam E. Tucker via Medscape, October 2024

buff.ly/48UxdFi

#EDS #MCAS #hEDS #HSD #POTS #Dysatuonomia #MastCells #Medicine #Science #Illness #ChronicIllness #NEISvoid #MedSky #Doctors #Zebras
buff.ly
August 19, 2025 at 5:14 AM
regisjoulia.bsky.social
🚨 We did it! Our latest work—led by my lab and the @lloydlab.bsky.social is now published in Nature Immunology! 🎉

Using single-cell spatial transcriptomics, we provide the first map of the airway wall.

🔗 www.nature.com/articles/s41...

#spatialbiology #asthma #mastcells #lungimmunology
A single-cell spatial chart of the airway wall reveals proinflammatory cellular ecosystems and their interactions in health and asthma - Nature Immunology
Here, the authors use single-cell spatial transcriptomics to profile the airway wall landscape in health and during asthma. Discrete proinflammatory ecosystems containing alarmins, chemokines and a un...
www.nature.com
May 21, 2025 at 4:40 PM
ohtwist.bsky.social
In which mast cells are found to not only emit lots of mediators, but occasionally ingest other white blood cells like neutrophils and either consume them, or emit their contents too...😮
www.sciencenews.org/article/some...

#MCAS #Masto #MastCells #Immunology #EDS #HSD #NEISvoid #MedSky
During an allergic response, some immune cells digest others
Mast cells lure and trap other immune cells during allergic reactions, using their compounds to increase inflammation in a process dubbed nexocytosis
www.sciencenews.org
April 24, 2025 at 3:03 AM
hindhussein.bsky.social
Our new paper is also out in Gut! gut.bmj.com/content/earl...
#Mastcells #IBS #GISky #Immunosky #MRGPRX2 #pain
Characterisation of MRGPRX2+ mast cells in irritable bowel syndrome
Background Mast cell activation is an important driver of abdominal pain in irritable bowel syndrome (IBS). While evidence supports the role of IgE-mediated mast cell activation in visceral pain devel...
gut.bmj.com
February 25, 2025 at 3:01 PM
achronicvoice.com
“It’s worth remembering that your #HistamineLoad is also influenced by your #environment and even the time of day, with #histamine levels peaking at night, when #MastCells are most active": buff.ly/jqGk8zi

#MCAS
via BBCGoodFood
What are high-histamine foods?
Think histamine is just about allergy? Think again. We take a look at what histamine is and how the food we eat may affect our histamine levels
buff.ly
April 7, 2025 at 7:30 AM
sellinlab.bsky.social
Congrats to our newly baked Dr. Christopher von Beek, who defended his thesis on #Mastcells and #bacterial #infection in stride. Hooray!
Thanks a lot to faculty opponent Jean Marshall and committee members Sanna Koskiniemi, Cecilia Andersson and Stefan Roos for the high-level sparring.
May 25, 2025 at 9:29 PM
achronicvoice.com
“some #histamine -producing #bacteria are..anaerobic, so vacuum-packing doesn’t inhibit them and higher levels of histamine are typically seen in leftover and out-of-date food.": buff.ly/pWItzIM

from BBCGoodFood
#leftovers #HealthyEating #Chronicillness #MastCells
What are high-histamine foods?
Think histamine is just about allergy? Think again. We take a look at what histamine is and how the food we eat may affect our histamine levels
buff.ly
November 19, 2025 at 9:30 AM
meduniwien.ac.at
📌 Insights into immunotherapy:

A study led by @philippstarkl.bsky.social​ reveals that #mastcells can influence #macrophages in unexpected ways—paving the way for immunomodulatory strategies. More on their role in inflammation & #immunedefence ⬇️

#MedUniVienna
New insights into the interaction between mast cells and macrophages
More about the study!
www.meduniwien.ac.at
July 2, 2025 at 11:09 AM
renegaderesearch.bsky.social
#MastCells #MastCellActivationSyndrome #MastCellActivation #MCAS #MCAD #HaT #Mastocytosis #MastCellActivationDisorder #MastCellDisorder #Neuroimmune #NeuroimmuneAxis #Histamine #Gastrointestinal #GastrointestinalHealth #GutBrain #GutBrainAxis
March 27, 2026 at 1:58 PM
ohtwist.bsky.social
In which mast cells are found to not only emit lots of mediators, but occasionally ingest other white blood cells like neutrophils and either consume them, or emit their contents too...😮
www.sciencenews.org/article/some...
#MCAS #Masto #MastCells #Immunology #EDS #HSD #NEISvoid #MedSky
During an allergic response, some immune cells digest others
Mast cells lure and trap other immune cells during allergic reactions, using their compounds to increase inflammation in a process dubbed nexocytosis
www.sciencenews.org
August 19, 2025 at 5:09 AM
achronicvoice.com
"It wasn’t until the 1950s that we learned that #MastCells release #histamine, a powerful #chemical responsible for the sneezing and runny nose of an #allergy, as well as #anaphylaxis, a life-threatening reaction.": buff.ly/UAQz5UE

via @discovermag.bsky.social
Allergic to Everything — The Mysteries of Mast Cells
How one of the oldest components of the human immune system can trigger a mysterious and little-understood syndrome.
buff.ly
August 28, 2025 at 7:30 AM