🧬 Meet Dr. Hanane Hadj-Moussa
Discover how re-engineering acetyl-CoA metabolism could unlock constitutive healthy aging—only at #AGEAnnualMeeting2025!
🔗 bit.ly/4cJx8Gd
#HealthyAging #AcetylCoA #MetabolicReprogramming #MitochondriaMatters #AGE2025
Discover how re-engineering acetyl-CoA metabolism could unlock constitutive healthy aging—only at #AGEAnnualMeeting2025!
🔗 bit.ly/4cJx8Gd
#HealthyAging #AcetylCoA #MetabolicReprogramming #MitochondriaMatters #AGE2025
April 29, 2025 at 2:54 PM
🧬 Meet Dr. Hanane Hadj-Moussa
Discover how re-engineering acetyl-CoA metabolism could unlock constitutive healthy aging—only at #AGEAnnualMeeting2025!
🔗 bit.ly/4cJx8Gd
#HealthyAging #AcetylCoA #MetabolicReprogramming #MitochondriaMatters #AGE2025
Discover how re-engineering acetyl-CoA metabolism could unlock constitutive healthy aging—only at #AGEAnnualMeeting2025!
🔗 bit.ly/4cJx8Gd
#HealthyAging #AcetylCoA #MetabolicReprogramming #MitochondriaMatters #AGE2025
GPR54 promotes progression & #MetabolicReprogramming in #NSCLC by enhancing dopa decarboxylase expression via the Gαq/11/PI3K/AKT/mTOR signaling pathway, underscoring its potential as both a #Biomarker & #TherapeuticTarget.
#OpenAccess: doi.org/10.1038/s413...
#OpenAccess: doi.org/10.1038/s413...
March 9, 2026 at 6:01 PM
GPR54 promotes progression & #MetabolicReprogramming in #NSCLC by enhancing dopa decarboxylase expression via the Gαq/11/PI3K/AKT/mTOR signaling pathway, underscoring its potential as both a #Biomarker & #TherapeuticTarget.
#OpenAccess: doi.org/10.1038/s413...
#OpenAccess: doi.org/10.1038/s413...
We are so thankful as we congratulate former lab member and outstanding scientist @npokorzynski.bsky.social on his appointment as Assistant Professor of Microbiology @oregonstate.edu #MetabolicReprogramming #proteolysis #antibioticsusceptibility microbiology.oregonstate.edu/directory/ni...
Nick Pokorzynski | Department of Microbiology
microbiology.oregonstate.edu
August 29, 2025 at 4:53 PM
We are so thankful as we congratulate former lab member and outstanding scientist @npokorzynski.bsky.social on his appointment as Assistant Professor of Microbiology @oregonstate.edu #MetabolicReprogramming #proteolysis #antibioticsusceptibility microbiology.oregonstate.edu/directory/ni...
Here we go again! A weekly selection of #anticancer #metabolicreprogramming
! Enjoy 🙂 biomed.news/bims-meract/...
🙏 @biomednews.bsky.social
! Enjoy 🙂 biomed.news/bims-meract/...
🙏 @biomednews.bsky.social
a cartoon drawing of a girl reading a book
ALT: a cartoon drawing of a girl reading a book
media.tenor.com
April 27, 2025 at 7:39 PM
Here we go again! A weekly selection of #anticancer #metabolicreprogramming
! Enjoy 🙂 biomed.news/bims-meract/...
🙏 @biomednews.bsky.social
! Enjoy 🙂 biomed.news/bims-meract/...
🙏 @biomednews.bsky.social
This review highlights #MetabolicReprogramming in #ClearCellRenalCellCarcinoma, covering glucose, lipid, amino acid & mitochondrial pathways, and #multiomics insights for therapy against #tumor progression.
#OpenAccess: doi.org/10.1016/j.ge...
#OpenAccess: doi.org/10.1016/j.ge...
December 29, 2025 at 12:49 PM
This review highlights #MetabolicReprogramming in #ClearCellRenalCellCarcinoma, covering glucose, lipid, amino acid & mitochondrial pathways, and #multiomics insights for therapy against #tumor progression.
#OpenAccess: doi.org/10.1016/j.ge...
#OpenAccess: doi.org/10.1016/j.ge...
Here is an exciting weekly selection of #anticancer #therapy and #metabolicreprogramming! Enjoy (pardon, running a bit late this week 😅)
biomed.news/bims-meract/...
🙏 @biomednews.bsky.social
biomed.news/bims-meract/...
🙏 @biomednews.bsky.social
the white rabbit from alice in wonderland is running with a clock on his back and says sorry running a little late
ALT: the white rabbit from alice in wonderland is running with a clock on his back and says sorry running a little late
media.tenor.com
March 3, 2026 at 6:06 AM
Here is an exciting weekly selection of #anticancer #therapy and #metabolicreprogramming! Enjoy (pardon, running a bit late this week 😅)
biomed.news/bims-meract/...
🙏 @biomednews.bsky.social
biomed.news/bims-meract/...
🙏 @biomednews.bsky.social
Scientists report #MetabolicReprogramming drives #DrugResistance in #HCC; AKR1B1 is a key regulator tied to poor prognosis, while #Epalrestat restores response, marking AKR1B1 as a #biomarker. @tsinghuauniversity.bsky.social
#CoverPage in #STTT: doi.org/10.1038/s413...
#CoverPage in #STTT: doi.org/10.1038/s413...
January 3, 2026 at 11:30 PM
Scientists report #MetabolicReprogramming drives #DrugResistance in #HCC; AKR1B1 is a key regulator tied to poor prognosis, while #Epalrestat restores response, marking AKR1B1 as a #biomarker. @tsinghuauniversity.bsky.social
#CoverPage in #STTT: doi.org/10.1038/s413...
#CoverPage in #STTT: doi.org/10.1038/s413...
This study details how mitochondrial #MetabolicReprogramming drives #Cancer growth, highlighting innovative therapeutic strategies targeting these metabolic dependencies to improve outcomes in precision cancer treatment.
#STTT #OpenAccess: doi.org/10.1038/s413...
#STTT #OpenAccess: doi.org/10.1038/s413...
June 2, 2026 at 2:30 PM
This study details how mitochondrial #MetabolicReprogramming drives #Cancer growth, highlighting innovative therapeutic strategies targeting these metabolic dependencies to improve outcomes in precision cancer treatment.
#STTT #OpenAccess: doi.org/10.1038/s413...
#STTT #OpenAccess: doi.org/10.1038/s413...
Available online - the Review "The HIF axes in cancer: #angiogenesis, metabolism, and immune-modulation" from Karen Acuña-Pilarte and Mei Yee Koh.
#Hypoxia #HIF #TumorMicroenvironment #MetabolicReprogramming #Therapeutics
Read it here: authors.elsevier.com/sd/article/S...
#Hypoxia #HIF #TumorMicroenvironment #MetabolicReprogramming #Therapeutics
Read it here: authors.elsevier.com/sd/article/S...
July 14, 2025 at 1:27 PM
Available online - the Review "The HIF axes in cancer: #angiogenesis, metabolism, and immune-modulation" from Karen Acuña-Pilarte and Mei Yee Koh.
#Hypoxia #HIF #TumorMicroenvironment #MetabolicReprogramming #Therapeutics
Read it here: authors.elsevier.com/sd/article/S...
#Hypoxia #HIF #TumorMicroenvironment #MetabolicReprogramming #Therapeutics
Read it here: authors.elsevier.com/sd/article/S...
Sharing a curated list of papers on #MetabolicReprogramming and #CancerTherapy - key insights into how metabolism drives treatment innovations. Follow for more updates! 🧬📚
biomed.news/bims-meract/...
Thanks @biomednews.bsky.social
biomed.news/bims-meract/...
Thanks @biomednews.bsky.social
a man wearing a michigan shirt is holding a book in his hand
ALT: a man wearing a michigan shirt is holding a book in his hand
media.tenor.com
December 2, 2024 at 8:07 AM
Sharing a curated list of papers on #MetabolicReprogramming and #CancerTherapy - key insights into how metabolism drives treatment innovations. Follow for more updates! 🧬📚
biomed.news/bims-meract/...
Thanks @biomednews.bsky.social
biomed.news/bims-meract/...
Thanks @biomednews.bsky.social
This review highlights the multifaceted mechanisms of #tumor #ImmuneEvasion, including checkpoint regulation, #TumorMicroenvironment dynamics & #MetabolicReprogramming, while discussing emerging #immunotherapies to curb resistance.
#STTT #OpenAccess: doi.org/10.1038/s413...
#STTT #OpenAccess: doi.org/10.1038/s413...
October 5, 2025 at 12:00 AM
This review highlights the multifaceted mechanisms of #tumor #ImmuneEvasion, including checkpoint regulation, #TumorMicroenvironment dynamics & #MetabolicReprogramming, while discussing emerging #immunotherapies to curb resistance.
#STTT #OpenAccess: doi.org/10.1038/s413...
#STTT #OpenAccess: doi.org/10.1038/s413...
Research reveals that iron-driven regulation of nucleotide synthesis creates specific metabolic vulnerabilities in #ColorectalCancer, highlighting potential #TherapeuticTargets linked to tumor #MetabolicReprogramming.
#OpenAccess: doi.org/10.1016/j.ge...
#OpenAccess: doi.org/10.1016/j.ge...
June 7, 2026 at 8:30 AM
Research reveals that iron-driven regulation of nucleotide synthesis creates specific metabolic vulnerabilities in #ColorectalCancer, highlighting potential #TherapeuticTargets linked to tumor #MetabolicReprogramming.
#OpenAccess: doi.org/10.1016/j.ge...
#OpenAccess: doi.org/10.1016/j.ge...
His research integrates stable isotope tracing, mass spectrometry, and systems biology to increase translational relevance while reducing animal use. #CancerMetabolism #SystemsBiology #TranslationalResearch #MetabolicReprogramming
November 14, 2025 at 2:05 PM
His research integrates stable isotope tracing, mass spectrometry, and systems biology to increase translational relevance while reducing animal use. #CancerMetabolism #SystemsBiology #TranslationalResearch #MetabolicReprogramming
This review shows how #MetabolicReprogramming drives #ColorectalCancer initiation, progression, resistance & recurrence, detailing #TumorMicroenvironment crosstalk and signaling, while highlighting metabolic #biomarkers for early diagnosis.
#OpenAccess: doi.org/10.1016/j.ge...
#OpenAccess: doi.org/10.1016/j.ge...
February 6, 2026 at 10:43 AM
This review shows how #MetabolicReprogramming drives #ColorectalCancer initiation, progression, resistance & recurrence, detailing #TumorMicroenvironment crosstalk and signaling, while highlighting metabolic #biomarkers for early diagnosis.
#OpenAccess: doi.org/10.1016/j.ge...
#OpenAccess: doi.org/10.1016/j.ge...
This review discusses #fattyacid-associated metabolic changes in #cancers and tumor–non-tumor cell interactions within the #TumorMicroenvironment, focusing on new targets for combination therapy with #MetabolicReprogramming and #immunotherapy. #medsky
#OpenAccess:
#OpenAccess:
www.sciencedirect.com
July 19, 2025 at 12:30 AM
This review discusses #fattyacid-associated metabolic changes in #cancers and tumor–non-tumor cell interactions within the #TumorMicroenvironment, focusing on new targets for combination therapy with #MetabolicReprogramming and #immunotherapy. #medsky
#OpenAccess:
#OpenAccess:
#Hypoglycemia activates SRF/MRTF-A–mediated #MetabolicReprogramming in #neurons, triggering #urea accumulation and #AlzheimersDisease-like #neurodegeneration, while glucose restoration suppresses this pathway and reverses damage. #Diabetes
#OpenAccess #STTT: doi.org/10.1038/s413...
#OpenAccess #STTT: doi.org/10.1038/s413...
February 10, 2026 at 2:00 AM
#Hypoglycemia activates SRF/MRTF-A–mediated #MetabolicReprogramming in #neurons, triggering #urea accumulation and #AlzheimersDisease-like #neurodegeneration, while glucose restoration suppresses this pathway and reverses damage. #Diabetes
#OpenAccess #STTT: doi.org/10.1038/s413...
#OpenAccess #STTT: doi.org/10.1038/s413...
#MetabolicReprogramming fuels #ColorectalCancer progression and therapy resistance.
This review explores its links to the tumor microenvironment, highlighting metabolic #biomarkers and targets for personalized treatment.
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...
This review explores its links to the tumor microenvironment, highlighting metabolic #biomarkers and targets for personalized treatment.
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...
August 18, 2026 at 3:54 PM
#MetabolicReprogramming fuels #ColorectalCancer progression and therapy resistance.
This review explores its links to the tumor microenvironment, highlighting metabolic #biomarkers and targets for personalized treatment.
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...
This review explores its links to the tumor microenvironment, highlighting metabolic #biomarkers and targets for personalized treatment.
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...
#OncostatinM induced by STAT5-activating #oncogenes triggers STAT-3-mediated proinflammatory signaling, resulting in #MetabolicReprogramming, enhanced cytokine secretion, and recruitment of #Immunosuppressive myeloid cells in blood malignancies.
#OpenAccess: doi.org/10.1038/s413...
#OpenAccess: doi.org/10.1038/s413...
December 16, 2025 at 8:32 PM
#OncostatinM induced by STAT5-activating #oncogenes triggers STAT-3-mediated proinflammatory signaling, resulting in #MetabolicReprogramming, enhanced cytokine secretion, and recruitment of #Immunosuppressive myeloid cells in blood malignancies.
#OpenAccess: doi.org/10.1038/s413...
#OpenAccess: doi.org/10.1038/s413...
Fatty acid oxidation is emerging as a key driver of tumor growth, survival, and treatment response, offering new opportunities for cancer therapy.
www.sciencedirect.com/science/arti...
#FattyAcidOxidation #CancerMetabolism #TumorGrowth #MetabolicReprogramming #CancerResearch
www.sciencedirect.com/science/arti...
#FattyAcidOxidation #CancerMetabolism #TumorGrowth #MetabolicReprogramming #CancerResearch
June 30, 2026 at 8:28 AM
Fatty acid oxidation is emerging as a key driver of tumor growth, survival, and treatment response, offering new opportunities for cancer therapy.
www.sciencedirect.com/science/arti...
#FattyAcidOxidation #CancerMetabolism #TumorGrowth #MetabolicReprogramming #CancerResearch
www.sciencedirect.com/science/arti...
#FattyAcidOxidation #CancerMetabolism #TumorGrowth #MetabolicReprogramming #CancerResearch
The methyltransferase SETDB1 catalyzes the dimethylation of CD147 at lysine 71 (CD147-K71me2), promoting tumor cell #apoptosis by upregulating FOSB expression and thereby inhibiting non-small cell lung cancer (#NSCLC) progression. #MetabolicReprogramming #ImmuneEvasion #medsky
www.sciencedirect.com
July 17, 2025 at 12:56 PM
The methyltransferase SETDB1 catalyzes the dimethylation of CD147 at lysine 71 (CD147-K71me2), promoting tumor cell #apoptosis by upregulating FOSB expression and thereby inhibiting non-small cell lung cancer (#NSCLC) progression. #MetabolicReprogramming #ImmuneEvasion #medsky
This review discusses the role of energy metabolism in health & disease, highlighting the role of #MetabolicReprogramming in the #Pathogenesis of various diseases, and emerging therapeutic strategies targeting metabolic pathways.
#STTT #OpenAccess: doi.org/10.1038/s413...
#STTT #OpenAccess: doi.org/10.1038/s413...
May 13, 2026 at 9:00 AM
This review discusses the role of energy metabolism in health & disease, highlighting the role of #MetabolicReprogramming in the #Pathogenesis of various diseases, and emerging therapeutic strategies targeting metabolic pathways.
#STTT #OpenAccess: doi.org/10.1038/s413...
#STTT #OpenAccess: doi.org/10.1038/s413...
This study from @pku1898.bsky.social reveals that FAK/Src axis-mediated tyrosine phosphorylation of metabolic enzymes accelerates tumor #Metastasis, linking mechanical signaling pathways to #MetabolicReprogramming.
#STTT #OpenAccess: doi.org/10.1038/s413...
#STTT #OpenAccess: doi.org/10.1038/s413...
June 2, 2026 at 1:45 AM
This study from @pku1898.bsky.social reveals that FAK/Src axis-mediated tyrosine phosphorylation of metabolic enzymes accelerates tumor #Metastasis, linking mechanical signaling pathways to #MetabolicReprogramming.
#STTT #OpenAccess: doi.org/10.1038/s413...
#STTT #OpenAccess: doi.org/10.1038/s413...
This review investigates the interplay between energy metabolism alterations & #ImmuneResponses in #HNSCC, highlights the key molecular players, and explores the therapeutic significance of #MetabolicReprogramming in HNSCC. #medsky
#OpenAccess: buff.ly/UESORJn
#OpenAccess: buff.ly/UESORJn
March 30, 2025 at 1:30 PM
This review investigates the interplay between energy metabolism alterations & #ImmuneResponses in #HNSCC, highlights the key molecular players, and explores the therapeutic significance of #MetabolicReprogramming in HNSCC. #medsky
#OpenAccess: buff.ly/UESORJn
#OpenAccess: buff.ly/UESORJn
Researchers show that TACC3-mediated lipid #MetabolicReprogramming suppresses CD8+ T-cell cytotoxicity in #HepatocellularCarcinoma, revealing a key mechanism of tumor #ImmuneEvasion and a potential #TherapeuticTarget.
#STTT #OpenAccess: doi.org/10.1038/s413...
#STTT #OpenAccess: doi.org/10.1038/s413...
June 10, 2026 at 6:58 AM
Researchers show that TACC3-mediated lipid #MetabolicReprogramming suppresses CD8+ T-cell cytotoxicity in #HepatocellularCarcinoma, revealing a key mechanism of tumor #ImmuneEvasion and a potential #TherapeuticTarget.
#STTT #OpenAccess: doi.org/10.1038/s413...
#STTT #OpenAccess: doi.org/10.1038/s413...
The FAK/Src family kinase axis contributes to #MetabolicReprogramming by inducing the phosphorylation of ATP-citrate synthase and fructose-bisphosphate aldolase A, to promote #metastasis in #ESCC cells. #medsky @pku1898.bsky.social
#OpenAccess:
#OpenAccess:
Focal adhesion kinase/Src family kinase axis-mediated tyrosine phosphorylation of metabolic enzymes facilitates tumor metastasis
Lymph node metastasis is crucial for esophageal squamous cell carcinoma (ESCC) malignancy. However, the molecular drivers and related mechanisms of lymph node metastasis in ESCC cells are unclear. In...
doi.org
September 12, 2025 at 3:30 PM
The FAK/Src family kinase axis contributes to #MetabolicReprogramming by inducing the phosphorylation of ATP-citrate synthase and fructose-bisphosphate aldolase A, to promote #metastasis in #ESCC cells. #medsky @pku1898.bsky.social
#OpenAccess:
#OpenAccess: