LOY was measured in blood cells
#UKBiobank
N=221k, 13.5 y f/up
#MassGeneralBrighamBiobank
N=14k
#AortaEd
@mariebillaud.bsky.social #JAMACardio 2026
jamanetwork.com/journals/jam...
LOY was measured in blood cells
#UKBiobank
N=221k, 13.5 y f/up
#MassGeneralBrighamBiobank
N=14k
#AortaEd
@mariebillaud.bsky.social #JAMACardio 2026
jamanetwork.com/journals/jam...
doi.org/10.1016/j.xg...
doi.org/10.1016/j.xg...
1. Our work on gene-environment interactions in the UKBiobank is up at the American Journal of Human Genetics
2. Our work on modeling ancient human population size history is up at Molecular Biology and Evolution
1. Our work on gene-environment interactions in the UKBiobank is up at the American Journal of Human Genetics
2. Our work on modeling ancient human population size history is up at Molecular Biology and Evolution
Y. Wang (Helsinki, Broad) show many shared features in biobanks
⏫ height
🫁 asthma
🫀 vascular risk
❓ driven by PAR gene dosage
#ESHG2026 #UKBiobank #AllofUs #FinnGen
Y. Wang (Helsinki, Broad) show many shared features in biobanks
⏫ height
🫁 asthma
🫀 vascular risk
❓ driven by PAR gene dosage
#ESHG2026 #UKBiobank #AllofUs #FinnGen
By @cgatist.bsky.social www.medrxiv.org/content/10.1...
Poster 5022W, Wed 2:30-4:30.
Poster 5022W, Wed 2:30-4:30.
EC TRIM35 E3 ligase KO➡️
⏬K63-Ub RelB NFκB subunit➡️
⏫MMP10➡️
⏫SMC #Osteogenesis
#UKBiobank plasma MMP10 ➕corr. CVD mortality & MACE
#FHS ➕corr. TAC score
#AdvSci 2025
advanced.onlinelibrary.wiley.com/doi/10.1002/...
EC TRIM35 E3 ligase KO➡️
⏬K63-Ub RelB NFκB subunit➡️
⏫MMP10➡️
⏫SMC #Osteogenesis
#UKBiobank plasma MMP10 ➕corr. CVD mortality & MACE
#FHS ➕corr. TAC score
#AdvSci 2025
advanced.onlinelibrary.wiley.com/doi/10.1002/...
#UKBiobank #Omics #HealthData
#UKBiobank #Omics #HealthData
昨天收到ukbiobank的緊急郵件,說分析平台暫時全部暫停。點進去看到CEO給全部的參加者發了信,數據發生洩漏,正在調查,向他們致歉。我還在猜是什麼情況。結果今天早上看到,是中國研究者在鹹魚上出售UKB數據。
昨天收到ukbiobank的緊急郵件,說分析平台暫時全部暫停。點進去看到CEO給全部的參加者發了信,數據發生洩漏,正在調查,向他們致歉。我還在猜是什麼情況。結果今天早上看到,是中國研究者在鹹魚上出售UKB數據。
This is not "in the public interest".
We need a serious review of the governance and leadership of UK Biobank.
#EpiSky
www.theguardian.com/world/2024/o...
This is not "in the public interest".
We need a serious review of the governance and leadership of UK Biobank.
#EpiSky
www.theguardian.com/world/2024/o...
Looking forward to diving into this one🙌🏼 What can it offer for T1D?🔬
www.cell.com/cell/fulltex...
Looking forward to diving into this one🙌🏼 What can it offer for T1D?🔬
Paper: doi.org/10.1093/jnci...
🧵👇
doi.org/10.1093/jnci...
@crukcamcentre.bsky.social
Paper: doi.org/10.1093/jnci...
🧵👇
#Diabetes
⬆️HbA1c level (even in normal range) is associated with ⬇️asc/desc thoracic aortic diameter & ⬇️risk for Aneurysm/Dissection
Multi-omics #UKBiobank Mendelian Randomization analyses➡️a causal link b/w glycemic traits / #T2D & TAAD risk
#JACCBTS 2025
www.jacc.org/doi/10.1016/...
#Diabetes
⬆️HbA1c level (even in normal range) is associated with ⬇️asc/desc thoracic aortic diameter & ⬇️risk for Aneurysm/Dissection
Multi-omics #UKBiobank Mendelian Randomization analyses➡️a causal link b/w glycemic traits / #T2D & TAAD risk
#JACCBTS 2025
www.jacc.org/doi/10.1016/...
✨ Speakers from industry (deCODE, Genomics), data (UKBiobank), experts from Oxford & beyond + an Editor from Nature Human Behaviour!
📸 More here 👉 www.demography.ox.ac.uk/news/lcds-ho...
✨ Speakers from industry (deCODE, Genomics), data (UKBiobank), experts from Oxford & beyond + an Editor from Nature Human Behaviour!
📸 More here 👉 www.demography.ox.ac.uk/news/lcds-ho...
#ASHG25
Learn more at my Poster 5058W, Wed 2:30pm #ASHG25
#ASHG25
R package for #UKBiobank data extraction
vs RAP ukbREST ukbtools
"automatically generates baseline characteristic tables"
"automatically identify the most suitable matched samples"
........
Fascinating🤓
But where's the code???🤒
#iMetaMed 2025
onlinelibrary.wiley.com/doi/10.1002/...
R package for #UKBiobank data extraction
vs RAP ukbREST ukbtools
"automatically generates baseline characteristic tables"
"automatically identify the most suitable matched samples"
........
Fascinating🤓
But where's the code???🤒
#iMetaMed 2025
onlinelibrary.wiley.com/doi/10.1002/...
Key result: importance to control for residual spatial confounding and lifestyle factors.
Focus on #reproducibility, with #R code & synthetic data.
Links: lnkd.in/dxY9SuGt
Key result: importance to control for residual spatial confounding and lifestyle factors.
Focus on #reproducibility, with #R code & synthetic data.
Links: lnkd.in/dxY9SuGt
Thanks to our collaborators & funders!
Thanks to our collaborators & funders!