📝 Online now - the Review "Emerging functions for nonhistone protein acetylation in budding yeast" from Michael Downey and colleagues.
#PostTranslationalModifications #DNADamageResponse #Proteostasis #Autophagy #MetabolicRegulation
Read it here: authors.elsevier.com/a/1m4nM3S6Gf...
#PostTranslationalModifications #DNADamageResponse #Proteostasis #Autophagy #MetabolicRegulation
Read it here: authors.elsevier.com/a/1m4nM3S6Gf...
November 12, 2025 at 2:28 PM
📝 Online now - the Review "Emerging functions for nonhistone protein acetylation in budding yeast" from Michael Downey and colleagues.
#PostTranslationalModifications #DNADamageResponse #Proteostasis #Autophagy #MetabolicRegulation
Read it here: authors.elsevier.com/a/1m4nM3S6Gf...
#PostTranslationalModifications #DNADamageResponse #Proteostasis #Autophagy #MetabolicRegulation
Read it here: authors.elsevier.com/a/1m4nM3S6Gf...
How iron helps collagen enzymes work - and what happens when it doesn’t #PostTranslationalModifications #DNAViruses #Dioxygenases doi.org/10.1107/S205...
June 18, 2025 at 1:41 PM
How iron helps collagen enzymes work - and what happens when it doesn’t #PostTranslationalModifications #DNAViruses #Dioxygenases doi.org/10.1107/S205...
Now online - the Review "A tale of two sugars: O-GlcNAc and O-fucose orchestrate growth, development, and acclimation in plants" from Zhi-Yong Wang et al @carnegiescience.bsky.social.
#proteomics #posttranslationalmodifications #plantdeveloment
Free access at: authors.elsevier.com/a/1kaow3S6Gf...
#proteomics #posttranslationalmodifications #plantdeveloment
Free access at: authors.elsevier.com/a/1kaow3S6Gf...
February 10, 2025 at 8:36 PM
Now online - the Review "A tale of two sugars: O-GlcNAc and O-fucose orchestrate growth, development, and acclimation in plants" from Zhi-Yong Wang et al @carnegiescience.bsky.social.
#proteomics #posttranslationalmodifications #plantdeveloment
Free access at: authors.elsevier.com/a/1kaow3S6Gf...
#proteomics #posttranslationalmodifications #plantdeveloment
Free access at: authors.elsevier.com/a/1kaow3S6Gf...
Can #PostTranslationalModifications reshape #CancerTherapy?
This review reveals how PTMs rewire tumor metabolism and highlights emerging acylation modifications as promising therapeutic targets. #Epigenetics
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...
This review reveals how PTMs rewire tumor metabolism and highlights emerging acylation modifications as promising therapeutic targets. #Epigenetics
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...
July 23, 2026 at 2:54 PM
Can #PostTranslationalModifications reshape #CancerTherapy?
This review reveals how PTMs rewire tumor metabolism and highlights emerging acylation modifications as promising therapeutic targets. #Epigenetics
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...
This review reveals how PTMs rewire tumor metabolism and highlights emerging acylation modifications as promising therapeutic targets. #Epigenetics
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...
🧠🧬 Publication! Our review explores microRNAs as early diagnostic tools for Alzheimer’s & Parkinson’s. Discover how these tiny molecules could reshape neurodegenerative disease detection.🔗 go.nature.com/3FSQrke
#MicroRNA#Neurodegeneration #PostTranslationalModifications#AgingAndDisease#Biomarkers
#MicroRNA#Neurodegeneration #PostTranslationalModifications#AgingAndDisease#Biomarkers
April 20, 2025 at 10:18 PM
🧠🧬 Publication! Our review explores microRNAs as early diagnostic tools for Alzheimer’s & Parkinson’s. Discover how these tiny molecules could reshape neurodegenerative disease detection.🔗 go.nature.com/3FSQrke
#MicroRNA#Neurodegeneration #PostTranslationalModifications#AgingAndDisease#Biomarkers
#MicroRNA#Neurodegeneration #PostTranslationalModifications#AgingAndDisease#Biomarkers
3/4 We identify novel substrates like #RPL22, #EIF3D and #PCM1, opening new doors to more functional insights into these #posttranslationalmodifications so far implicated primarily in #microtubule regulation. Their role in #cellbiology seems more than what is thought to be.
June 12, 2026 at 1:50 AM
3/4 We identify novel substrates like #RPL22, #EIF3D and #PCM1, opening new doors to more functional insights into these #posttranslationalmodifications so far implicated primarily in #microtubule regulation. Their role in #cellbiology seems more than what is thought to be.
This review highlights how novel #PostTranslationalModifications—propionylation, butyrylation, #crotonylation, succinylation, glutarylation—contribute to #fibrosis progression, offering new therapeutic targets for #AntiFibrotic interventions.
#OpenAccess: doi.org/10.1016/j.ge...
#OpenAccess: doi.org/10.1016/j.ge...
April 24, 2026 at 4:30 PM
This review highlights how novel #PostTranslationalModifications—propionylation, butyrylation, #crotonylation, succinylation, glutarylation—contribute to #fibrosis progression, offering new therapeutic targets for #AntiFibrotic interventions.
#OpenAccess: doi.org/10.1016/j.ge...
#OpenAccess: doi.org/10.1016/j.ge...
This review highlights how #PostTranslationalModifications coordinate #InfluenzaVirus infection—from entry and replication to immune evasion—revealing interconnected regulatory networks and new opportunities for #antiviral and #vaccine development.
Read: doi.org/10.1016/j.ge...
Read: doi.org/10.1016/j.ge...
June 10, 2026 at 4:44 PM
This review highlights how #PostTranslationalModifications coordinate #InfluenzaVirus infection—from entry and replication to immune evasion—revealing interconnected regulatory networks and new opportunities for #antiviral and #vaccine development.
Read: doi.org/10.1016/j.ge...
Read: doi.org/10.1016/j.ge...
This review summarizes the physiological functions of protein #Citrullination and outlines the recent progress in understanding its role in #genetranscription regulation, particularly in relation to other #PostTranslationalModifications. #medsky
#OpenAccess: www.sciencedirect.com/science/arti...
#OpenAccess: www.sciencedirect.com/science/arti...
April 28, 2025 at 4:02 PM
This review summarizes the physiological functions of protein #Citrullination and outlines the recent progress in understanding its role in #genetranscription regulation, particularly in relation to other #PostTranslationalModifications. #medsky
#OpenAccess: www.sciencedirect.com/science/arti...
#OpenAccess: www.sciencedirect.com/science/arti...
Tingfei Chen et al.: Structure of an Fe2+-binding-deficient mimiviral collagen lysyl hydroxylase ##PostTranslationalModifications##DNAViruses##Dioxygenases@MedUniGraz...##IUCrhttps://journals.iucr.org/paper?S2053230X25003735
Structure of an Fe2+-binding-deficient mimiviral collagen lysyl hydroxylase
Fe2+ binding stabilizes collagen lysyl hydroxylase dimers, although the underlying mechanism remains unclear. Here, we report the crystal structure of an Fe2+-binding-deficient mimiviral collagen lysyl hydroxylase, highlighting the conformational changes upon loss of Fe2+ binding.
journals.iucr.org
May 3, 2025 at 12:00 AM
Tingfei Chen et al.: Structure of an Fe2+-binding-deficient mimiviral collagen lysyl hydroxylase ##PostTranslationalModifications##DNAViruses##Dioxygenases@MedUniGraz...##IUCrhttps://journals.iucr.org/paper?S2053230X25003735
Lucy C. Schofield et al.: Post-translational modifications in the Protein Data Bank ##PostTranslationalModifications##ProteinDataBank##Glycosylation@uniofyork@Cambridge_Uni...##IUCrhttps://journals.iucr.org/paper?S2059798324007794
Post-translational modifications in the Protein Data Bank
This review explores the importance of post-translational modifications (PTMs) in the Protein Data Bank and identifies examples of well modelled PTMs.
journals.iucr.org
August 30, 2024 at 12:00 AM
Lucy C. Schofield et al.: Post-translational modifications in the Protein Data Bank ##PostTranslationalModifications##ProteinDataBank##Glycosylation@uniofyork@Cambridge_Uni...##IUCrhttps://journals.iucr.org/paper?S2059798324007794
The role of post-translational modifications in influencing protein structure and function, and the frequency and representation of these modifications in the PDB, are examined #PostTranslationalModifications #ProteinDataBank #Glycosylation t.co/iocwcaTdCy
September 17, 2024 at 1:40 PM
The role of post-translational modifications in influencing protein structure and function, and the frequency and representation of these modifications in the PDB, are examined #PostTranslationalModifications #ProteinDataBank #Glycosylation t.co/iocwcaTdCy
🔔 Our December Issue is here online! 🎄 ☃️
buff.ly/JGyxzCF
✨ Dive into our Reviews, Commentary, and Original Research Articles, including Editor’s Choice.
#StructuralBiology #GeneRegulation #PosttranslationalModifications #GenotoxicAgents #CellularStressResponse
buff.ly/JGyxzCF
✨ Dive into our Reviews, Commentary, and Original Research Articles, including Editor’s Choice.
#StructuralBiology #GeneRegulation #PosttranslationalModifications #GenotoxicAgents #CellularStressResponse
December 15, 2025 at 9:24 AM
🔔 Our December Issue is here online! 🎄 ☃️
buff.ly/JGyxzCF
✨ Dive into our Reviews, Commentary, and Original Research Articles, including Editor’s Choice.
#StructuralBiology #GeneRegulation #PosttranslationalModifications #GenotoxicAgents #CellularStressResponse
buff.ly/JGyxzCF
✨ Dive into our Reviews, Commentary, and Original Research Articles, including Editor’s Choice.
#StructuralBiology #GeneRegulation #PosttranslationalModifications #GenotoxicAgents #CellularStressResponse
This review maps the structural and functional landscape of #Panx1, detailing its physiological roles, #PostTranslationalModifications, and activation mechanisms, with implications for #CardiovascularHealth and disease.
Read More: tinyurl.com/25w78tqw
Read More: tinyurl.com/25w78tqw
June 24, 2026 at 1:24 PM
This review maps the structural and functional landscape of #Panx1, detailing its physiological roles, #PostTranslationalModifications, and activation mechanisms, with implications for #CardiovascularHealth and disease.
Read More: tinyurl.com/25w78tqw
Read More: tinyurl.com/25w78tqw
This review highlights how #PostTranslationalModifications regulate #PDL1 stability and function in #BreastCancer, shaping response variability to PD-1/PD-L1 therapy and offering new targets for #PersonalizedImmunotherapy optimization.
#OpenAccess: doi.org/10.1016/j.ge...
#OpenAccess: doi.org/10.1016/j.ge...
April 24, 2026 at 2:30 PM
This review highlights how #PostTranslationalModifications regulate #PDL1 stability and function in #BreastCancer, shaping response variability to PD-1/PD-L1 therapy and offering new targets for #PersonalizedImmunotherapy optimization.
#OpenAccess: doi.org/10.1016/j.ge...
#OpenAccess: doi.org/10.1016/j.ge...
This review highlights how #histone #PostTranslationalModifications dynamically regulate #chromatin and gene expression in #CVDs, revealing their mechanistic roles and therapeutic potential alongside current challenges and future prospects.
#OpenAccess: doi.org/10.1016/j.ge...
#OpenAccess: doi.org/10.1016/j.ge...
April 2, 2026 at 12:52 PM
This review highlights how #histone #PostTranslationalModifications dynamically regulate #chromatin and gene expression in #CVDs, revealing their mechanistic roles and therapeutic potential alongside current challenges and future prospects.
#OpenAccess: doi.org/10.1016/j.ge...
#OpenAccess: doi.org/10.1016/j.ge...
A review on LSD1 structure and the amino acid residues influencing its #EnzymaticActivity, with insights into its #PostTranslationalModifications, their effects on cellular processes, and the #Diseases associated with its abnormal expression.
#OpenAccess: doi.org/10.1016/j.ge...
#OpenAccess: doi.org/10.1016/j.ge...
January 13, 2026 at 5:30 PM
A review on LSD1 structure and the amino acid residues influencing its #EnzymaticActivity, with insights into its #PostTranslationalModifications, their effects on cellular processes, and the #Diseases associated with its abnormal expression.
#OpenAccess: doi.org/10.1016/j.ge...
#OpenAccess: doi.org/10.1016/j.ge...
This extensive review explores the structural features, #posttranslationalmodifications, and disease-related roles of #LSD1 and provides valuable insights into the potential therapeutic implications of targeting LSD1 and its modifications in various diseases. #medsky
#OpenAccess: buff.ly/tMPQBLy
#OpenAccess: buff.ly/tMPQBLy
March 9, 2025 at 3:00 PM
This extensive review explores the structural features, #posttranslationalmodifications, and disease-related roles of #LSD1 and provides valuable insights into the potential therapeutic implications of targeting LSD1 and its modifications in various diseases. #medsky
#OpenAccess: buff.ly/tMPQBLy
#OpenAccess: buff.ly/tMPQBLy